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Items: 1 to 20 of 208

1.

Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ.

Powell E, Shanle E, Brinkman A, Li J, Keles S, Wisinski KB, Huang W, Xu W.

PLoS One. 2012;7(2):e30993. doi: 10.1371/journal.pone.0030993. Epub 2012 Feb 7.

2.

Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands.

Shanle EK, Hawse JR, Xu W.

Biochem Pharmacol. 2011 Dec 15;82(12):1940-9. doi: 10.1016/j.bcp.2011.08.026. Epub 2011 Sep 6.

3.

Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen.

Wu X, Subramaniam M, Grygo SB, Sun Z, Negron V, Lingle WL, Goetz MP, Ingle JN, Spelsberg TC, Hawse JR.

Breast Cancer Res. 2011 Mar 10;13(2):R27. doi: 10.1186/bcr2844.

4.

Genistein in the presence of 17beta-estradiol inhibits proliferation of ERbeta breast cancer cells.

Rajah TT, Du N, Drews N, Cohn R.

Pharmacology. 2009;84(2):68-73. doi: 10.1159/000226123. Epub 2009 Jun 26.

PMID:
19556829
5.

Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft.

Saxena R, Fatima I, Chandra V, Blesson CS, Kharkwal G, Hussain MK, Hajela K, Roy BG, Dwivedi A.

Steroids. 2013 Nov;78(11):1071-86. doi: 10.1016/j.steroids.2013.07.004. Epub 2013 Jul 26.

PMID:
23891847
6.

Estrogen receptor alpha/beta isoforms, but not betacx, modulate unique patterns of gene expression and cell proliferation in Hs578T cells.

Secreto FJ, Monroe DG, Dutta S, Ingle JN, Spelsberg TC.

J Cell Biochem. 2007 Aug 1;101(5):1125-47.

PMID:
17520659
7.

A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells.

Williams C, Edvardsson K, Lewandowski SA, Ström A, Gustafsson JA.

Oncogene. 2008 Feb 7;27(7):1019-32. Epub 2007 Aug 13.

PMID:
17700529
8.

Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells.

Cotrim CZ, Fabris V, Doria ML, Lindberg K, Gustafsson JÅ, Amado F, Lanari C, Helguero LA.

Oncogene. 2013 May 9;32(19):2390-402. doi: 10.1038/onc.2012.261. Epub 2012 Jul 2.

PMID:
22751110
9.

Estrogen receptor beta in breast cancer.

Palmieri C, Cheng GJ, Saji S, Zelada-Hedman M, Wärri A, Weihua Z, Van Noorden S, Wahlstrom T, Coombes RC, Warner M, Gustafsson JA.

Endocr Relat Cancer. 2002 Mar;9(1):1-13. Review.

10.

Intermolecular interactions identify ligand-selective activity of estrogen receptor alpha/beta dimers.

Powell E, Xu W.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):19012-7. doi: 10.1073/pnas.0807274105. Epub 2008 Nov 20.

11.

Human T47D-ERβ breast cancer cells with tetracycline-dependent ERβ expression reflect ERα/ERβ ratios in rat and human breast tissue.

Evers NM, van de Klundert TM, van Aesch YM, Wang S, de Roos WK, Romano A, de Haan LH, Murk AJ, Ederveen AG, Rietjens IM, Groten JP.

Toxicol In Vitro. 2013 Sep;27(6):1753-61. doi: 10.1016/j.tiv.2013.04.014. Epub 2013 May 13.

PMID:
23680332
12.

Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression.

Harrington WR, Sheng S, Barnett DH, Petz LN, Katzenellenbogen JA, Katzenellenbogen BS.

Mol Cell Endocrinol. 2003 Aug 29;206(1-2):13-22.

PMID:
12943986
13.

Estrogen receptor beta exerts growth-inhibitory effects on human mammary epithelial cells.

Treeck O, Lattrich C, Springwald A, Ortmann O.

Breast Cancer Res Treat. 2010 Apr;120(3):557-65. doi: 10.1007/s10549-009-0413-2. Epub 2009 May 12.

PMID:
19434490
14.

Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation.

Grober OM, Mutarelli M, Giurato G, Ravo M, Cicatiello L, De Filippo MR, Ferraro L, Nassa G, Papa MF, Paris O, Tarallo R, Luo S, Schroth GP, Benes V, Weisz A.

BMC Genomics. 2011 Jan 14;12:36. doi: 10.1186/1471-2164-12-36.

15.

Expression of estrogen receptors-alpha and -beta in bladder cancer cell lines and human bladder tumor tissue.

Shen SS, Smith CL, Hsieh JT, Yu J, Kim IY, Jian W, Sonpavde G, Ayala GE, Younes M, Lerner SP.

Cancer. 2006 Jun 15;106(12):2610-6.

16.

Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β.

Galea GL, Meakin LB, Sugiyama T, Zebda N, Sunters A, Taipaleenmaki H, Stein GS, van Wijnen AJ, Lanyon LE, Price JS.

J Biol Chem. 2013 Mar 29;288(13):9035-48. doi: 10.1074/jbc.M112.405456. Epub 2013 Jan 29.

17.

Preferential estrogen receptor β ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagy.

Ruddy SC, Lau R, Cabrita MA, McGregor C, McKay BC, Murphy LC, Wright JS, Durst T, Pratt MA.

Mol Cancer Ther. 2014 Jul;13(7):1882-93. doi: 10.1158/1535-7163.MCT-13-1066. Epub 2014 Apr 30.

18.

Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells.

Chang EC, Frasor J, Komm B, Katzenellenbogen BS.

Endocrinology. 2006 Oct;147(10):4831-42. Epub 2006 Jun 29.

PMID:
16809442
19.

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology.

Katzenellenbogen BS, Choi I, Delage-Mourroux R, Ediger TR, Martini PG, Montano M, Sun J, Weis K, Katzenellenbogen JA.

J Steroid Biochem Mol Biol. 2000 Nov 30;74(5):279-85. Review.

PMID:
11162936
20.

Ligand-induced regulation of ERalpha and ERbeta is indicative of human breast cancer cell proliferation.

Power KA, Thompson LU.

Breast Cancer Res Treat. 2003 Oct;81(3):209-21.

PMID:
14620916
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