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Results: 1 to 20 of 92

1.

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.

Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R.

Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909.

PMID:
22314321
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanisms promoting translocations in editing and switching peripheral B cells.

Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW.

Nature. 2009 Jul 9;460(7252):231-6. doi: 10.1038/nature08159.

PMID:
19587764
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Translocation capture sequencing: a method for high throughput mapping of chromosomal rearrangements.

Oliveira TY, Resch W, Jankovic M, Casellas R, Nussenzweig MC, Klein IA.

J Immunol Methods. 2012 Jan 31;375(1-2):176-81. doi: 10.1016/j.jim.2011.10.007. Epub 2011 Oct 18.

PMID:
22033343
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC.

Nature. 2006 Mar 2;440(7080):105-9. Epub 2006 Jan 8.

PMID:
16400328
[PubMed - indexed for MEDLINE]
5.

AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.

Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC.

Cell. 2008 Dec 12;135(6):1028-38. doi: 10.1016/j.cell.2008.09.062.

PMID:
19070574
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC.

Cell. 2011 Sep 30;147(1):95-106. doi: 10.1016/j.cell.2011.07.048.

PMID:
21962510
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Immunology: B cells break the rules.

Diaz M, Daly J.

Nature. 2009 Jul 9;460(7252):184-6. doi: 10.1038/460184a. No abstract available.

PMID:
19587755
[PubMed - indexed for MEDLINE]
8.

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.

Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC.

Mol Cell. 2009 Nov 25;36(4):631-41. doi: 10.1016/j.molcel.2009.11.007.

PMID:
19941823
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Role of the translocation partner in protection against AID-dependent chromosomal translocations.

Jankovic M, Robbiani DF, Dorsett Y, Eisenreich T, Xu Y, Tarakhovsky A, Nussenzweig A, Nussenzweig MC.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):187-92. doi: 10.1073/pnas.0908946107. Epub 2009 Dec 4.

PMID:
19966290
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.

Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW.

Mol Cell. 2006 Jan 20;21(2):201-14.

PMID:
16427010
[PubMed - indexed for MEDLINE]
Free Article
11.

A role for AID in chromosome translocations between c-myc and the IgH variable region.

Dorsett Y, Robbiani DF, Jankovic M, Reina-San-Martin B, Eisenreich TR, Nussenzweig MC.

J Exp Med. 2007 Sep 3;204(9):2225-32. Epub 2007 Aug 27. Erratum in: J Exp Med. 2007 Oct;204(10):2491.

PMID:
17724134
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.

Chiarle R, Zhang Y, Frock RL, Lewis SM, Molinie B, Ho YJ, Myers DR, Choi VW, Compagno M, Malkin DJ, Neuberg D, Monti S, Giallourakis CC, Gostissa M, Alt FW.

Cell. 2011 Sep 30;147(1):107-19. doi: 10.1016/j.cell.2011.07.049. Erratum in: Cell. 2011 Dec 23;147(7):1640.

PMID:
21962511
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

Gostissa M, Yan CT, Bianco JM, Cogné M, Pinaud E, Alt FW.

Nature. 2009 Dec 10;462(7274):803-7. doi: 10.1038/nature08633.

PMID:
20010689
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.

Dorsett Y, McBride KM, Jankovic M, Gazumyan A, Thai TH, Robbiani DF, Di Virgilio M, Reina San-Martin B, Heidkamp G, Schwickert TA, Eisenreich T, Rajewsky K, Nussenzweig MC.

Immunity. 2008 May;28(5):630-8. doi: 10.1016/j.immuni.2008.04.002. Epub 2008 May 1.

PMID:
18455451
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes.

Wright SM, Woo YH, Alley TL, Shirley BJ, Akeson EC, Snow KJ, Maas SA, Elwell RL, Foreman O, Mills KD.

Cancer Res. 2009 May 15;69(10):4454-60. doi: 10.1158/0008-5472.CAN-08-4515. Epub 2009 May 12.

PMID:
19435904
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.

Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3034-9. doi: 10.1073/pnas.0915067107. Epub 2010 Jan 25. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.

PMID:
20133803
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations.

Rowh MA, DeMicco A, Horowitz JE, Yin B, Yang-Iott KS, Fusello AM, Hobeika E, Reth M, Bassing CH.

Oncogene. 2011 Nov 24;30(47):4757-64. doi: 10.1038/onc.2011.191. Epub 2011 May 30.

PMID:
21625223
[PubMed - indexed for MEDLINE]
18.

The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.

Rocha PP, Skok JA.

Curr Opin Cell Biol. 2013 Jun;25(3):365-71. doi: 10.1016/j.ceb.2013.02.007. Epub 2013 Mar 13. Review.

PMID:
23478218
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Along came a spider: AID escapes a microRNA web.

Desiderio S.

Immunity. 2008 May;28(5):596-8. doi: 10.1016/j.immuni.2008.04.012.

PMID:
18482561
[PubMed - indexed for MEDLINE]
Free Article
20.

Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.

Kovalchuk AL, Ansarah-Sobrinho C, Hakim O, Resch W, Tolarová H, Dubois W, Yamane A, Takizawa M, Klein I, Hager GL, Morse HC 3rd, Potter M, Nussenzweig MC, Casellas R.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10972-7. doi: 10.1073/pnas.1200106109. Epub 2012 Jun 18.

PMID:
22711821
[PubMed - indexed for MEDLINE]
Free PMC Article

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