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Items: 1 to 20 of 95

1.

B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.

Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL, Yarovinsky F.

Immunity. 2012 Feb 24;36(2):228-38. doi: 10.1016/j.immuni.2011.11.019. Epub 2012 Feb 1.

2.

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18.

Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, Wang E, Ma W, Haines D, O'hUigin C, Marincola FM, Trinchieri G.

J Exp Med. 2010 Aug 2;207(8):1625-36. doi: 10.1084/jem.20100199. Epub 2010 Jul 12.

3.

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis.

Gibson DL, Ma C, Bergstrom KS, Huang JT, Man C, Vallance BA.

Cell Microbiol. 2008 Mar;10(3):618-31. Epub 2007 Nov 2.

PMID:
17979981
4.

Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.

Asquith MJ, Boulard O, Powrie F, Maloy KJ.

Gastroenterology. 2010 Aug;139(2):519-29, 529.e1-2. doi: 10.1053/j.gastro.2010.04.045. Epub 2010 Apr 28.

5.

MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis.

Araki A, Kanai T, Ishikura T, Makita S, Uraushihara K, Iiyama R, Totsuka T, Takeda K, Akira S, Watanabe M.

J Gastroenterol. 2005 Jan;40(1):16-23.

PMID:
15692785
6.

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernández-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M.

Nature. 2011 Jul 31;477(7364):330-4. doi: 10.1038/nature10273.

PMID:
21804564
7.

Colonic epithelial response to injury requires Myd88 signaling in myeloid cells.

Malvin NP, Seno H, Stappenbeck TS.

Mucosal Immunol. 2012 Mar;5(2):194-206. doi: 10.1038/mi.2011.65. Epub 2012 Jan 18.

8.

Regulation of the polymeric immunoglobulin receptor in intestinal epithelial cells by Enterobacteriaceae: implications for mucosal homeostasis.

Bruno ME, Rogier EW, Frantz AL, Stefka AT, Thompson SN, Kaetzel CS.

Immunol Invest. 2010;39(4-5):356-82. doi: 10.3109/08820131003622809.

PMID:
20450283
9.

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

Brandl K, Sun L, Neppl C, Siggs OM, Le Gall SM, Tomisato W, Li X, Du X, Maennel DN, Blobel CP, Beutler B.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19967-72. doi: 10.1073/pnas.1014669107. Epub 2010 Nov 1.

10.
11.

Campylobacter jejuni disrupts protective Toll-like receptor 9 signaling in colonic epithelial cells and increases the severity of dextran sulfate sodium-induced colitis in mice.

O'Hara JR, Feener TD, Fischer CD, Buret AG.

Infect Immun. 2012 Apr;80(4):1563-71. doi: 10.1128/IAI.06066-11. Epub 2012 Feb 6.

12.
13.

Host genetics and environmental factors regulate ecological succession of the mouse colon tissue-associated microbiota.

Smith P, Siddharth J, Pearson R, Holway N, Shaxted M, Butler M, Clark N, Jamontt J, Watson RP, Sanmugalingam D, Parkinson SJ.

PLoS One. 2012;7(1):e30273. doi: 10.1371/journal.pone.0030273. Epub 2012 Jan 17.

14.

MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice.

Aviello G, Corr SC, Johnston DG, O'Neill LA, Fallon PG.

Am J Physiol Gastrointest Liver Physiol. 2014 May 1;306(9):G769-78. doi: 10.1152/ajpgi.00399.2013. Epub 2014 Mar 6.

15.

Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides.

Frantz AL, Rogier EW, Weber CR, Shen L, Cohen DA, Fenton LA, Bruno ME, Kaetzel CS.

Mucosal Immunol. 2012 Sep;5(5):501-12. doi: 10.1038/mi.2012.23. Epub 2012 Apr 11.

16.

Depletion of gut commensal bacteria attenuates intestinal ischemia/reperfusion injury.

Yoshiya K, Lapchak PH, Thai TH, Kannan L, Rani P, Dalle Lucca JJ, Tsokos GC.

Am J Physiol Gastrointest Liver Physiol. 2011 Dec;301(6):G1020-30. doi: 10.1152/ajpgi.00239.2011. Epub 2011 Sep 8.

17.

MyD88-dependent signaling protects against anthrax lethal toxin-induced impairment of intestinal barrier function.

Okugawa S, Moayeri M, Eckhaus MA, Crown D, Miller-Randolph S, Liu S, Akira S, Leppla SH.

Infect Immun. 2011 Jan;79(1):118-24. doi: 10.1128/IAI.00963-10. Epub 2010 Oct 25.

18.

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface.

Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20858-63. doi: 10.1073/pnas.0808723105. Epub 2008 Dec 15.

19.

MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands.

Into T, Takigawa T, Niida S, Shibata K.

PLoS One. 2014 Nov 21;9(11):e113333. doi: 10.1371/journal.pone.0113333. eCollection 2014.

20.

Bacterial stimulation of the TLR-MyD88 pathway modulates the homeostatic expression of ileal Paneth cell ╬▒-defensins.

Menendez A, Willing BP, Montero M, Wlodarska M, So CC, Bhinder G, Vallance BA, Finlay BB.

J Innate Immun. 2013;5(1):39-49. doi: 10.1159/000341630. Epub 2012 Sep 14.

PMID:
22986642
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