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Items: 1 to 20 of 220

1.

Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.

Jahan I, Pan N, Kersigo J, Calisto LE, Morris KA, Kopecky B, Duncan JS, Beisel KW, Fritzsch B.

PLoS One. 2012;7(1):e30853. doi: 10.1371/journal.pone.0030853. Epub 2012 Jan 24.

2.

Neurog1 can partially substitute for Atoh1 function in hair cell differentiation and maintenance during organ of Corti development.

Jahan I, Pan N, Kersigo J, Fritzsch B.

Development. 2015 Aug 15;142(16):2810-21. doi: 10.1242/dev.123091. Epub 2015 Jul 24.

3.

A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability.

Pan N, Jahan I, Kersigo J, Duncan JS, Kopecky B, Fritzsch B.

PLoS One. 2012;7(1):e30358. doi: 10.1371/journal.pone.0030358. Epub 2012 Jan 18.

4.

Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.

Jahan I, Pan N, Kersigo J, Fritzsch B.

PLoS One. 2010 Jul 22;5(7):e11661. doi: 10.1371/journal.pone.0011661.

5.

Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.

Pan N, Jahan I, Kersigo J, Kopecky B, Santi P, Johnson S, Schmitz H, Fritzsch B.

Hear Res. 2011 May;275(1-2):66-80. doi: 10.1016/j.heares.2010.12.002. Epub 2010 Dec 10.

6.

Beyond generalized hair cells: molecular cues for hair cell types.

Jahan I, Pan N, Kersigo J, Fritzsch B.

Hear Res. 2013 Mar;297:30-41. doi: 10.1016/j.heares.2012.11.008. Epub 2012 Nov 27. Review.

7.

Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti.

Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK.

J Neurosci. 2013 Jun 12;33(24):10110-22. doi: 10.1523/JNEUROSCI.5606-12.2013.

8.

Atoh1 directs hair cell differentiation and survival in the late embryonic mouse inner ear.

Chonko KT, Jahan I, Stone J, Wright MC, Fujiyama T, Hoshino M, Fritzsch B, Maricich SM.

Dev Biol. 2013 Sep 15;381(2):401-10. doi: 10.1016/j.ydbio.2013.06.022. Epub 2013 Jun 21.

9.

Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit.

Matei V, Pauley S, Kaing S, Rowitch D, Beisel KW, Morris K, Feng F, Jones K, Lee J, Fritzsch B.

Dev Dyn. 2005 Nov;234(3):633-50.

10.

Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention.

Fritzsch B, Matei VA, Nichols DH, Bermingham N, Jones K, Beisel KW, Wang VY.

Dev Dyn. 2005 Jun;233(2):570-83.

11.

Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea.

Stojanova ZP, Kwan T, Segil N.

Development. 2015 Oct 15;142(20):3529-36. doi: 10.1242/dev.126763. Erratum in: Development. 2016 May 1;143(9):1632.

12.

Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.

Pan N, Kopecky B, Jahan I, Fritzsch B.

Cell Tissue Res. 2012 Aug;349(2):415-32. doi: 10.1007/s00441-012-1454-0. Epub 2012 Jun 13. Review.

13.

Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency.

Mulvaney J, Dabdoub A.

J Assoc Res Otolaryngol. 2012 Jun;13(3):281-93. doi: 10.1007/s10162-012-0317-4. Epub 2012 Feb 28. Review.

14.

Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development.

Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P.

BMC Dev Biol. 2008 Feb 26;8:20. doi: 10.1186/1471-213X-8-20.

15.

Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development.

Raft S, Koundakjian EJ, Quinones H, Jayasena CS, Goodrich LV, Johnson JE, Segil N, Groves AK.

Development. 2007 Dec;134(24):4405-15.

16.

Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens.

Lewis RM, Hume CR, Stone JS.

Hear Res. 2012 Jul;289(1-2):74-85. doi: 10.1016/j.heares.2012.04.008. Epub 2012 Apr 20.

17.

Rbpj regulates development of prosensory cells in the mammalian inner ear.

Yamamoto N, Chang W, Kelley MW.

Dev Biol. 2011 May 15;353(2):367-79. doi: 10.1016/j.ydbio.2011.03.016. Epub 2011 Mar 21.

18.

Dissecting the molecular basis of organ of Corti development: Where are we now?

Fritzsch B, Jahan I, Pan N, Kersigo J, Duncan J, Kopecky B.

Hear Res. 2011 Jun;276(1-2):16-26. doi: 10.1016/j.heares.2011.01.007. Epub 2011 Jan 21. Review.

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