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Items: 1 to 20 of 109

1.

Structural evidence for cooperative microtubule stabilization by Taxol and the endogenous dynamics regulator MAP4.

Xiao H, Wang H, Zhang X, Tu Z, Bulinski C, Khrapunovich-Baine M, Hogue Angeletti R, Horwitz SB.

ACS Chem Biol. 2012 Apr 20;7(4):744-52. doi: 10.1021/cb200403x. Epub 2012 Feb 6.

2.

Insights into the mechanism of microtubule stabilization by Taxol.

Xiao H, Verdier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB, Orr GA.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10166-73. Epub 2006 Jun 26.

3.

Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.

Khrapunovich-Baine M, Menon V, Verdier-Pinard P, Smith AB 3rd, Angeletti RH, Fiser A, Horwitz SB, Xiao H.

Biochemistry. 2009 Dec 15;48(49):11664-77. doi: 10.1021/bi901351q.

4.

Radial compression of microtubules and the mechanism of action of taxol and associated proteins.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Ewert K, Miller HP, Wilson L, Safinya CR.

Biophys J. 2005 Nov;89(5):3410-23. Epub 2005 Aug 12.

5.

Truncation of the projection domain of MAP4 (microtubule-associated protein 4) leads to attenuation of microtubule dynamic instability.

Permana S, Hisanaga S, Nagatomo Y, Iida J, Hotani H, Itoh TJ.

Cell Struct Funct. 2005 Feb;29(5-6):147-57.

6.

The projection domain of MAP4 suppresses the microtubule-bundling activity of the microtubule-binding domain.

Iida J, Itoh TJ, Hotani H, Nishiyama K, Murofushi H, Bulinski JC, Hisanaga S.

J Mol Biol. 2002 Jun 28;320(1):97-106.

PMID:
12079337
7.

Removal of MAP4 from microtubules in vivo produces no observable phenotype at the cellular level.

Wang XM, Peloquin JG, Zhai Y, Bulinski JC, Borisy GG.

J Cell Biol. 1996 Feb;132(3):345-57.

8.

Overexpression of full- or partial-length MAP4 stabilizes microtubules and alters cell growth.

Nguyen HL, Chari S, Gruber D, Lue CM, Chapin SJ, Bulinski JC.

J Cell Sci. 1997 Jan;110 ( Pt 2):281-94.

9.

Substoichiometric binding of taxol suppresses microtubule dynamics.

Derry WB, Wilson L, Jordan MA.

Biochemistry. 1995 Feb 21;34(7):2203-11.

PMID:
7857932
10.
11.

Tau induces cooperative Taxol binding to microtubules.

Ross JL, Santangelo CD, Makrides V, Fygenson DK.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12910-5. Epub 2004 Aug 23.

12.

Cellular microtubules heterogeneous in their content of microtubule-associated protein 4 (MAP4).

Chapin SJ, Bulinski JC.

Cell Motil Cytoskeleton. 1994;27(2):133-49.

PMID:
7909279
13.

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

Martello LA, Verdier-Pinard P, Shen HJ, He L, Torres K, Orr GA, Horwitz SB.

Cancer Res. 2003 Mar 15;63(6):1207-13.

14.

Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation.

Khrapunovich-Baine M, Menon V, Yang CP, Northcote PT, Miller JH, Angeletti RH, Fiser A, Horwitz SB, Xiao H.

J Biol Chem. 2011 Apr 1;286(13):11765-78. doi: 10.1074/jbc.M110.162214. Epub 2011 Jan 18.

15.

MAP4 counteracts microtubule catastrophe promotion but not tubulin-sequestering activity in intact cells.

Holmfeldt P, Brattsand G, Gullberg M.

Curr Biol. 2002 Jun 25;12(12):1034-9.

16.

Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Miller HP, Li Y, Song C, Feinstein SC, Wilson L, Choi MC, Safinya CR.

Faraday Discuss. 2013;166:31-45.

17.

Overexpression of MAP4 inhibits organelle motility and trafficking in vivo.

Bulinski JC, McGraw TE, Gruber D, Nguyen HL, Sheetz MP.

J Cell Sci. 1997 Dec;110 ( Pt 24):3055-64.

18.

DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4.

Zhang CC, Yang JM, Bash-Babula J, White E, Murphy M, Levine AJ, Hait WN.

Cancer Res. 1999 Aug 1;59(15):3663-70.

19.

Tau-isoform dependent enhancement of taxol mobility through microtubules.

Park H, Kim M, Fygenson DK.

Arch Biochem Biophys. 2008 Oct 1;478(1):119-26. doi: 10.1016/j.abb.2008.07.020. Epub 2008 Jul 26.

PMID:
18691553
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