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Results: 1 to 20 of 151

1.

Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain.

Tillu DV, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ.

Mol Pain. 2012 Jan 23;8:5. doi: 10.1186/1744-8069-8-5.

PMID:
22269797
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain.

Melemedjian OK, Asiedu MN, Tillu DV, Sanoja R, Yan J, Lark A, Khoutorsky A, Johnson J, Peebles KA, Lepow T, Sonenberg N, Dussor G, Price TJ.

Mol Pain. 2011 Sep 21;7:70. doi: 10.1186/1744-8069-7-70.

PMID:
21936900
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex.

Melemedjian OK, Asiedu MN, Tillu DV, Peebles KA, Yan J, Ertz N, Dussor GO, Price TJ.

J Neurosci. 2010 Nov 10;30(45):15113-23. doi: 10.1523/JNEUROSCI.3947-10.2010.

PMID:
21068317
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The red wine polyphenol resveratrol shows promising potential for the treatment of nucleus pulposus-mediated pain in vitro and in vivo.

Wuertz K, Quero L, Sekiguchi M, Klawitter M, Nerlich A, Konno S, Kikuchi S, Boos N.

Spine (Phila Pa 1976). 2011 Oct 1;36(21):E1373-84. doi: 10.1097/BRS.0b013e318221e655.

PMID:
21587103
[PubMed - indexed for MEDLINE]
5.

Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation.

Lin JN, Lin VC, Rau KM, Shieh PC, Kuo DH, Shieh JC, Chen WJ, Tsai SC, Way TD.

J Agric Food Chem. 2010 Feb 10;58(3):1584-92. doi: 10.1021/jf9035782.

PMID:
19928762
[PubMed - indexed for MEDLINE]
6.

BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state.

Melemedjian OK, Tillu DV, Asiedu MN, Mandell EK, Moy JK, Blute VM, Taylor CJ, Ghosh S, Price TJ.

Mol Pain. 2013 Mar 20;9:12. doi: 10.1186/1744-8069-9-12.

PMID:
23510079
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Resveratrol inhibits protein translation in hepatic cells.

Villa-Cuesta E, Boylan JM, Tatar M, Gruppuso PA.

PLoS One. 2011;6(12):e29513. doi: 10.1371/journal.pone.0029513. Epub 2011 Dec 29.

PMID:
22242130
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision.

Sahbaie P, Shi X, Guo TZ, Qiao Y, Yeomans DC, Kingery WS, Clark JD.

Pain. 2009 Oct;145(3):341-9. doi: 10.1016/j.pain.2009.06.037. Epub 2009 Aug 5.

PMID:
19660865
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway.

Yuan Y, Xue X, Guo RB, Sun XL, Hu G.

CNS Neurosci Ther. 2012 Jul;18(7):536-46. doi: 10.1111/j.1755-5949.2012.00319.x. Epub 2012 Apr 25.

PMID:
22530672
[PubMed - indexed for MEDLINE]
10.

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice.

Kim MY, Lim JH, Youn HH, Hong YA, Yang KS, Park HS, Chung S, Ko SH, Shin SJ, Choi BS, Kim HW, Kim YS, Lee JH, Chang YS, Park CW.

Diabetologia. 2013 Jan;56(1):204-17. doi: 10.1007/s00125-012-2747-2. Epub 2012 Oct 23. Erratum in: Diabetologia. 2013 Mar;56(3):681. Koh, S H [corrected to Ko, S H].

PMID:
23090186
[PubMed - indexed for MEDLINE]
11.

Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization.

Asiedu MN, Tillu DV, Melemedjian OK, Shy A, Sanoja R, Bodell B, Ghosh S, Porreca F, Price TJ.

J Neurosci. 2011 May 4;31(18):6646-53. doi: 10.1523/JNEUROSCI.6286-10.2011.

PMID:
21543593
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes.

Roy Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P.

Brain. 2012 Jun;135(Pt 6):1751-66. doi: 10.1093/brain/aws097. Epub 2012 May 4.

PMID:
22561641
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.

Zhong LM, Zong Y, Sun L, Guo JZ, Zhang W, He Y, Song R, Wang WM, Xiao CJ, Lu D.

PLoS One. 2012;7(2):e32195. doi: 10.1371/journal.pone.0032195. Epub 2012 Feb 21.

PMID:
22363816
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

2-Arylthiazolidine-4-carboxylic acid amides (ATCAA) target dual pathways in cancer cells: 5'-AMP-activated protein kinase (AMPK)/mTOR and PI3K/Akt/mTOR pathways.

Li CM, Narayanan R, Lu Y, Hurh E, Coss CC, Barrett CM, Miller DD, Dalton JT.

Int J Oncol. 2010 Oct;37(4):1023-30.

PMID:
20811725
[PubMed - indexed for MEDLINE]
15.

mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.

Melemedjian OK, Khoutorsky A, Sorge RE, Yan J, Asiedu MN, Valdez A, Ghosh S, Dussor G, Mogil JS, Sonenberg N, Price TJ.

Pain. 2013 Jul;154(7):1080-91. doi: 10.1016/j.pain.2013.03.021. Epub 2013 Mar 15.

PMID:
23607966
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Biphasic activation of extracellular signal-regulated kinase in anterior cingulate cortex distinctly regulates the development of pain-related anxiety and mechanical hypersensitivity in rats after incision.

Dai RP, Li CQ, Zhang JW, Li F, Shi XD, Zhang JY, Zhou XF.

Anesthesiology. 2011 Sep;115(3):604-13. doi: 10.1097/ALN.0b013e3182242045.

PMID:
21670662
[PubMed - indexed for MEDLINE]
Free Article
17.

Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease.

Wu Y, Li X, Zhu JX, Xie W, Le W, Fan Z, Jankovic J, Pan T.

Neurosignals. 2011;19(3):163-74. doi: 10.1159/000328516. Epub 2011 Jul 22.

PMID:
21778691
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts.

Venkatachalam K, Mummidi S, Cortez DM, Prabhu SD, Valente AJ, Chandrasekar B.

Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2078-87. doi: 10.1152/ajpheart.01363.2007. Epub 2008 Feb 29.

PMID:
18310510
[PubMed - indexed for MEDLINE]
Free Article
19.

Antinociceptive effect of Mirabilis jalapa on acute and chronic pain models in mice.

Walker CI, Trevisan G, Rossato MF, Silva CR, Pinheiro FV, Franciscato C, Tatsch E, Moretto MB, Silva MD, Manfron MP, Noal Moresco R, Santos AR, Pereira ME, Ferreira J.

J Ethnopharmacol. 2013 Oct 7;149(3):685-93. doi: 10.1016/j.jep.2013.07.027. Epub 2013 Jul 29.

PMID:
23906783
[PubMed - indexed for MEDLINE]
20.

Intraplantar PGE2 causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases.

Kassuya CA, Ferreira J, Claudino RF, Calixto JB.

Br J Pharmacol. 2007 Mar;150(6):727-37. Epub 2007 Feb 19.

PMID:
17310141
[PubMed - indexed for MEDLINE]
Free PMC Article

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