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Items: 1 to 20 of 90


Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response.

Stewart MK, Cummings LA, Johnson ML, Berezow AB, Cookson BT.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20742-7. doi: 10.1073/pnas.1108963108. Epub 2011 Dec 5.


Innate immune detection of flagellin positively and negatively regulates salmonella infection.

Lai MA, Quarles EK, López-Yglesias AH, Zhao X, Hajjar AM, Smith KD.

PLoS One. 2013 Aug 19;8(8):e72047. doi: 10.1371/journal.pone.0072047. eCollection 2013.


In vivo, fliC expression by Salmonella enterica serovar Typhimurium is heterogeneous, regulated by ClpX, and anatomically restricted.

Cummings LA, Wilkerson WD, Bergsbaken T, Cookson BT.

Mol Microbiol. 2006 Aug;61(3):795-809. Epub 2006 Jun 27.


Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages.

Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozören N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Núñez G.

Nat Immunol. 2006 Jun;7(6):576-82. Epub 2006 Apr 30.


Mutually repressing repressor functions and multi-layered cellular heterogeneity regulate the bistable Salmonella fliC census.

Stewart MK, Cookson BT.

Mol Microbiol. 2014 Dec;94(6):1272-84. doi: 10.1111/mmi.12828. Epub 2014 Oct 31.


Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf.

Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, Aderem A.

Nat Immunol. 2006 Jun;7(6):569-75. Epub 2006 Apr 30.


In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of S. typhimurium can proceed in the absence of flagellin.

Hoffmann C, Galle M, Dilling S, Käppeli R, Müller AJ, Songhet P, Beyaert R, Hardt WD.

PLoS One. 2010 Aug 30;5(8):e12477. doi: 10.1371/journal.pone.0012477.


Toll-like receptor 5-dependent regulation of inflammation in systemic Salmonella enterica Serovar typhimurium infection.

Fournier B, Williams IR, Gewirtz AT, Neish AS.

Infect Immun. 2009 Sep;77(9):4121-9. doi: 10.1128/IAI.00656-09. Epub 2009 Jul 13.


Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity.

Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE.

PLoS Pathog. 2006 Mar;2(3):e18. Epub 2006 Mar 17.


FliC-specific CD4+ T cell responses are restricted by bacterial regulation of antigen expression.

Cummings LA, Barrett SL, Wilkerson WD, Fellnerova I, Cookson BT.

J Immunol. 2005 Jun 15;174(12):7929-38.


Mutation of flgM attenuates virulence of Salmonella typhimurium, and mutation of fliA represses the attenuated phenotype.

Schmitt CK, Darnell SC, Tesh VL, Stocker BA, O'Brien AD.

J Bacteriol. 1994 Jan;176(2):368-77.


Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway.

Lyons S, Wang L, Casanova JE, Sitaraman SV, Merlin D, Gewirtz AT.

J Cell Sci. 2004 Nov 15;117(Pt 24):5771-80. Epub 2004 Oct 26.


A rapid change in virulence gene expression during the transition from the intestinal lumen into tissue promotes systemic dissemination of Salmonella.

Winter SE, Winter MG, Godinez I, Yang HJ, Rüssmann H, Andrews-Polymenis HL, Bäumler AJ.

PLoS Pathog. 2010 Aug 19;6(8):e1001060. doi: 10.1371/journal.ppat.1001060.


Regulatory protein that inhibits both synthesis and use of the target protein controls flagellar phase variation in Salmonella enterica.

Aldridge PD, Wu C, Gnerer J, Karlinsey JE, Hughes KT, Sachs MS.

Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11340-5. Epub 2006 Jul 14.

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