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Items: 1 to 20 of 107

1.

Structure-based analysis of VDAC1 protein: defining oligomer contact sites.

Geula S, Naveed H, Liang J, Shoshan-Barmatz V.

J Biol Chem. 2012 Jan 13;287(3):2179-90. doi: 10.1074/jbc.M111.268920. Epub 2011 Nov 23.

2.

VDAC1 cysteine residues: topology and function in channel activity and apoptosis.

Aram L, Geula S, Arbel N, Shoshan-Barmatz V.

Biochem J. 2010 Apr 14;427(3):445-54. doi: 10.1042/BJ20091690. Erratum in: Biochem J. 2010 Jul 14;429(3):613-4.

PMID:
20192921
3.

Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo.

Shoshan-Barmatz V, Keinan N, Abu-Hamad S, Tyomkin D, Aram L.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1281-91. doi: 10.1016/j.bbabio.2010.03.003. Epub 2010 Mar 6.

4.

Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins.

Geula S, Ben-Hail D, Shoshan-Barmatz V.

Biochem J. 2012 Jun 15;444(3):475-85. doi: 10.1042/BJ20112079.

PMID:
22397371
5.

Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis.

Keinan N, Tyomkin D, Shoshan-Barmatz V.

Mol Cell Biol. 2010 Dec;30(24):5698-709. doi: 10.1128/MCB.00165-10. Epub 2010 Oct 11.

6.

The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis.

Keinan N, Pahima H, Ben-Hail D, Shoshan-Barmatz V.

Biochim Biophys Acta. 2013 Jul;1833(7):1745-54. doi: 10.1016/j.bbamcr.2013.03.017. Epub 2013 Mar 28.

7.

Oligomerization of the mitochondrial protein VDAC1: from structure to function and cancer therapy.

Shoshan-Barmatz V, Mizrachi D, Keinan N.

Prog Mol Biol Transl Sci. 2013;117:303-34. doi: 10.1016/B978-0-12-386931-9.00011-8. Review.

PMID:
23663973
8.

Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase.

Shoshan-Barmatz V, Zakar M, Rosenthal K, Abu-Hamad S.

Biochim Biophys Acta. 2009 May;1787(5):421-30. doi: 10.1016/j.bbabio.2008.11.009. Epub 2008 Nov 27.

9.

Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis.

Mader A, Abu-Hamad S, Arbel N, GutiƩrrez-Aguilar M, Shoshan-Barmatz V.

Biochem J. 2010 Jul 1;429(1):147-55. doi: 10.1042/BJ20091338. Erratum in: Biochem J. 2010 Jul 14;429(3):613. Gutierr-Asuilar, Manuel [corrected to GutiƩrrez-Aguilar, Manuel].

PMID:
20420578
10.

Ca(2+)-mediated regulation of VDAC1 expression levels is associated with cell death induction.

Weisthal S, Keinan N, Ben-Hail D, Arif T, Shoshan-Barmatz V.

Biochim Biophys Acta. 2014 Oct;1843(10):2270-81. doi: 10.1016/j.bbamcr.2014.03.021. Epub 2014 Apr 1.

11.

An N-terminal nucleotide-binding site in VDAC1: involvement in regulating mitochondrial function.

Yehezkel G, Abu-Hamad S, Shoshan-Barmatz V.

J Cell Physiol. 2007 Aug;212(2):551-61.

PMID:
17503466
12.

Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein.

Arbel N, Ben-Hail D, Shoshan-Barmatz V.

J Biol Chem. 2012 Jun 29;287(27):23152-61. doi: 10.1074/jbc.M112.345918. Epub 2012 May 15.

13.

Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding.

Abu-Hamad S, Zaid H, Israelson A, Nahon E, Shoshan-Barmatz V.

J Biol Chem. 2008 May 9;283(19):13482-90. doi: 10.1074/jbc.M708216200. Epub 2008 Feb 28.

14.

The mitochondrial voltage-dependent anion channel 1 in tumor cells.

Shoshan-Barmatz V, Ben-Hail D, Admoni L, Krelin Y, Tripathi SS.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2547-75. doi: 10.1016/j.bbamem.2014.10.040. Epub 2014 Nov 4. Review.

PMID:
25448878
15.

Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation.

Ujwal R, Cascio D, Chaptal V, Ping P, Abramson J.

Channels (Austin). 2009 May-Jun;3(3):167-70. Epub 2009 May 15.

16.

Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity.

Arbel N, Shoshan-Barmatz V.

J Biol Chem. 2010 Feb 26;285(9):6053-62. doi: 10.1074/jbc.M109.082990. Epub 2009 Dec 26.

17.

Structure of the human voltage-dependent anion channel.

Bayrhuber M, Meins T, Habeck M, Becker S, Giller K, Villinger S, Vonrhein C, Griesinger C, Zweckstetter M, Zeth K.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15370-5. doi: 10.1073/pnas.0808115105. Epub 2008 Oct 1.

18.

Mapping the ruthenium red-binding site of the voltage-dependent anion channel-1.

Israelson A, Zaid H, Abu-Hamad S, Nahon E, Shoshan-Barmatz V.

Cell Calcium. 2008 Feb;43(2):196-204. Epub 2007 Jun 27.

PMID:
17590433
19.

The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins.

Abu-Hamad S, Arbel N, Calo D, Arzoine L, Israelson A, Keinan N, Ben-Romano R, Friedman O, Shoshan-Barmatz V.

J Cell Sci. 2009 Jun 1;122(Pt 11):1906-16. doi: 10.1242/jcs.040188.

20.

Molecular model of hexokinase binding to the outer mitochondrial membrane porin (VDAC1): Implication for the design of new cancer therapies.

Rosano C.

Mitochondrion. 2011 May;11(3):513-9. doi: 10.1016/j.mito.2011.01.012. Epub 2011 Feb 20.

PMID:
21315184
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