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Results: 1 to 20 of 106

1.

Linking neurodevelopmental and synaptic theories of mental illness through DISC1.

Brandon NJ, Sawa A.

Nat Rev Neurosci. 2011 Nov 18;12(12):707-22. doi: 10.1038/nrn3120. Review.

PMID:
22095064
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Understanding the role of DISC1 in psychiatric disease and during normal development.

Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A.

J Neurosci. 2009 Oct 14;29(41):12768-75. doi: 10.1523/JNEUROSCI.3355-09.2009. Review.

PMID:
19828788
[PubMed - indexed for MEDLINE]
Free Article
3.

DISC1 at 10: connecting psychiatric genetics and neuroscience.

Porteous DJ, Millar JK, Brandon NJ, Sawa A.

Trends Mol Med. 2011 Dec;17(12):699-706. doi: 10.1016/j.molmed.2011.09.002. Epub 2011 Oct 19. Review.

PMID:
22015021
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The DISC locus in psychiatric illness.

Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK.

Mol Psychiatry. 2008 Jan;13(1):36-64. Epub 2007 Oct 2. Review.

PMID:
17912248
[PubMed - indexed for MEDLINE]
5.

DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness.

Millar JK, James R, Brandon NJ, Thomson PA.

Ann Med. 2004;36(5):367-78. Review.

PMID:
15478311
[PubMed - indexed for MEDLINE]
6.

DISC1: a key lead in studying cortical development and associated brain disorders.

Narayan S, Nakajima K, Sawa A.

Neuroscientist. 2013 Oct;19(5):451-64. doi: 10.1177/1073858412470168. Epub 2013 Jan 8. Review.

PMID:
23300216
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.

Hennah W, Porteous D.

PLoS One. 2009;4(3):e4906. doi: 10.1371/journal.pone.0004906. Epub 2009 Mar 20.

PMID:
19300510
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.

Hennah W, Thomson P, Peltonen L, Porteous D.

Schizophr Bull. 2006 Jul;32(3):409-16. Epub 2006 May 12. Review.

PMID:
16699061
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).

Matsuzaki S, Tohyama M.

Neurochem Int. 2007 Jul-Sep;51(2-4):165-72. Epub 2007 Jun 27. Review.

PMID:
17664024
[PubMed - indexed for MEDLINE]
10.

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV.

Mol Psychiatry. 2011 Mar;16(3):293-306. doi: 10.1038/mp.2009.144. Epub 2010 Jan 5.

PMID:
20048751
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

[Neurodevelopmental disturbance in the pathogenesis of major mental disorders].

Kamiya A, Kitabatake Y, Sawa A.

Brain Nerve. 2008 Apr;60(4):445-52. Review. Japanese.

PMID:
18421986
[PubMed - indexed for MEDLINE]
12.

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, Mori S, Moran TH, Ross CA.

Mol Psychiatry. 2008 Feb;13(2):173-86, 115. Epub 2007 Sep 11.

PMID:
17848917
[PubMed - indexed for MEDLINE]
13.

DISC1 in schizophrenia: genetic mouse models and human genomic imaging.

Johnstone M, Thomson PA, Hall J, McIntosh AM, Lawrie SM, Porteous DJ.

Schizophr Bull. 2011 Jan;37(1):14-20. doi: 10.1093/schbul/sbq135. Epub 2010 Dec 13. Review.

PMID:
21149852
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.

Millar JK, Mackie S, Clapcote SJ, Murdoch H, Pickard BS, Christie S, Muir WJ, Blackwood DH, Roder JC, Houslay MD, Porteous DJ.

J Physiol. 2007 Oct 15;584(Pt 2):401-5. Epub 2007 Sep 6. Review.

PMID:
17823207
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

Schurov IL, Handford EJ, Brandon NJ, Whiting PJ.

Mol Psychiatry. 2004 Dec;9(12):1100-10.

PMID:
15381924
[PubMed - indexed for MEDLINE]
16.

DISC1 as a therapeutic target for mental illnesses.

Hikida T, Gamo NJ, Sawa A.

Expert Opin Ther Targets. 2012 Dec;16(12):1151-60. doi: 10.1517/14728222.2012.719879. Epub 2012 Nov 6. Review.

PMID:
23130881
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Schizophrenia in translation: disrupted in schizophrenia (DISC1): integrating clinical and basic findings.

Roberts RC.

Schizophr Bull. 2007 Jan;33(1):11-5. Epub 2006 Nov 30. Review.

PMID:
17138582
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses.

Sawamura N, Sawa A.

Ann N Y Acad Sci. 2006 Nov;1086:126-33. Review.

PMID:
17185511
[PubMed - indexed for MEDLINE]
19.

Role of DISC1 in neural development and schizophrenia.

Mackie S, Millar JK, Porteous DJ.

Curr Opin Neurobiol. 2007 Feb;17(1):95-102. Epub 2007 Jan 26. Review.

PMID:
17258902
[PubMed - indexed for MEDLINE]
20.

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders.

Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, Camargo LM, Oliver KR, Beher D, Shearman MS, Whiting PJ.

Mol Cell Neurosci. 2004 Jan;25(1):42-55.

PMID:
14962739
[PubMed - indexed for MEDLINE]

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