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Results: 1 to 20 of 104

1.

A conformational switch in the CRIB-PDZ module of Par-6.

Whitney DS, Peterson FC, Volkman BF.

Structure. 2011 Nov 9;19(11):1711-22. doi: 10.1016/j.str.2011.07.018.

PMID:
22078569
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Allosteric activation of the Par-6 PDZ via a partial unfolding transition.

Whitney DS, Peterson FC, Kovrigin EL, Volkman BF.

J Am Chem Soc. 2013 Jun 26;135(25):9377-83. doi: 10.1021/ja400092a. Epub 2013 Jun 12.

PMID:
23705660
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition.

Peterson FC, Penkert RR, Volkman BF, Prehoda KE.

Mol Cell. 2004 Mar 12;13(5):665-76.

PMID:
15023337
[PubMed - indexed for MEDLINE]
Free Article
4.

Internal recognition through PDZ domain plasticity in the Par-6-Pals1 complex.

Penkert RR, DiVittorio HM, Prehoda KE.

Nat Struct Mol Biol. 2004 Nov;11(11):1122-7. Epub 2004 Oct 10.

PMID:
15475968
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6.

Garrard SM, Capaldo CT, Gao L, Rosen MK, Macara IG, Tomchick DR.

EMBO J. 2003 Mar 3;22(5):1125-33.

PMID:
12606577
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Interactions between the PDZ domains of Bazooka (Par-3) and phosphatidic acid: in vitro characterization and role in epithelial development.

Yu CG, Harris TJ.

Mol Biol Cell. 2012 Sep;23(18):3743-53. doi: 10.1091/mbc.E12-03-0196. Epub 2012 Jul 25.

PMID:
22833561
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A bivalent dissectional analysis of the high-affinity interactions between Cdc42 and the Cdc42/Rac interactive binding domains of signaling kinases in Candida albicans.

Su Z, Osborne MJ, Xu P, Xu X, Li Y, Ni F.

Biochemistry. 2005 Dec 20;44(50):16461-74.

PMID:
16342938
[PubMed - indexed for MEDLINE]
8.

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation.

Rudolph MG, Bayer P, Abo A, Kuhlmann J, Vetter IR, Wittinghofer A.

J Biol Chem. 1998 Jul 17;273(29):18067-76.

PMID:
9660763
[PubMed - indexed for MEDLINE]
Free Article
9.

Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.

Amacher JF, Cushing PR, Bahl CD, Beck T, Madden DR.

J Biol Chem. 2013 Feb 15;288(7):5114-26. doi: 10.1074/jbc.M112.401588. Epub 2012 Dec 15.

PMID:
23243314
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement.

Graybill C, Wee B, Atwood SX, Prehoda KE.

J Biol Chem. 2012 Jun 15;287(25):21003-11. doi: 10.1074/jbc.M112.360495. Epub 2012 Apr 27.

PMID:
22544755
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegans.

Li J, Kim H, Aceto DG, Hung J, Aono S, Kemphues KJ.

Dev Biol. 2010 Apr 1;340(1):88-98. doi: 10.1016/j.ydbio.2010.01.023. Epub 2010 Feb 1.

PMID:
20122916
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The role of flexibility and conformational selection in the binding promiscuity of PDZ domains.

Münz M, Hein J, Biggin PC.

PLoS Comput Biol. 2012;8(11):e1002749. doi: 10.1371/journal.pcbi.1002749. Epub 2012 Nov 1.

PMID:
23133356
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Crystal structure of a PDZ domain.

Morais Cabral JH, Petosa C, Sutcliffe MJ, Raza S, Byron O, Poy F, Marfatia SM, Chishti AH, Liddington RC.

Nature. 1996 Aug 15;382(6592):649-52.

PMID:
8757139
[PubMed - indexed for MEDLINE]
14.

Beyond the binding site: the role of the β₂-β₃ loop and extra-domain structures in PDZ domains.

Mostarda S, Gfeller D, Rao F.

PLoS Comput Biol. 2012;8(3):e1002429. doi: 10.1371/journal.pcbi.1002429. Epub 2012 Mar 8.

PMID:
22412368
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif.

Chimura T, Launey T, Ito M.

BMC Genomics. 2011 Jun 8;12:300. doi: 10.1186/1471-2164-12-300.

PMID:
21649932
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

Yamanaka T, Horikoshi Y, Suzuki A, Sugiyama Y, Kitamura K, Maniwa R, Nagai Y, Yamashita A, Hirose T, Ishikawa H, Ohno S.

Genes Cells. 2001 Aug;6(8):721-31.

PMID:
11532031
[PubMed - indexed for MEDLINE]
18.

An allosteric intramolecular PDZ-PDZ interaction modulates PTP-BL PDZ2 binding specificity.

van den Berk LC, Landi E, Walma T, Vuister GW, Dente L, Hendriks WJ.

Biochemistry. 2007 Nov 27;46(47):13629-37. Epub 2007 Nov 3.

PMID:
17979300
[PubMed - indexed for MEDLINE]
19.

Molecular determinants for the complex binding specificity of the PDZ domain in PICK1.

Madsen KL, Beuming T, Niv MY, Chang CW, Dev KK, Weinstein H, Gether U.

J Biol Chem. 2005 May 27;280(21):20539-48. Epub 2005 Mar 17.

PMID:
15774468
[PubMed - indexed for MEDLINE]
Free Article
20.

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.

Abdul-Manan N, Aghazadeh B, Liu GA, Majumdar A, Ouerfelli O, Siminovitch KA, Rosen MK.

Nature. 1999 May 27;399(6734):379-83.

PMID:
10360578
[PubMed - indexed for MEDLINE]

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