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Results: 1 to 20 of 118

1.

Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex.

Schulz C, Lytovchenko O, Melin J, Chacinska A, Guiard B, Neumann P, Ficner R, Jahn O, Schmidt B, Rehling P.

J Cell Biol. 2011 Nov 14;195(4):643-56. doi: 10.1083/jcb.201105098. Epub 2011 Nov 7.

PMID:
22065641
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.

Yamamoto H, Esaki M, Kanamori T, Tamura Y, Nishikawa Si, Endo T.

Cell. 2002 Nov 15;111(4):519-28.

PMID:
12437925
[PubMed - indexed for MEDLINE]
Free Article
3.

Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes.

Gebert M, Schrempp SG, Mehnert CS, Heißwolf AK, Oeljeklaus S, Ieva R, Bohnert M, von der Malsburg K, Wiese S, Kleinschroth T, Hunte C, Meyer HE, Haferkamp I, Guiard B, Warscheid B, Pfanner N, van der Laan M.

J Cell Biol. 2012 May 28;197(5):595-604. doi: 10.1083/jcb.201110047. Epub 2012 May 21.

PMID:
22613836
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel.

Geissler A, Chacinska A, Truscott KN, Wiedemann N, Brandner K, Sickmann A, Meyer HE, Meisinger C, Pfanner N, Rehling P.

Cell. 2002 Nov 15;111(4):507-18.

PMID:
12437924
[PubMed - indexed for MEDLINE]
Free Article
5.

Signal recognition initiates reorganization of the presequence translocase during protein import.

Lytovchenko O, Melin J, Schulz C, Kilisch M, Hutu DP, Rehling P.

EMBO J. 2013 Mar 20;32(6):886-98. doi: 10.1038/emboj.2013.23. Epub 2013 Feb 12.

PMID:
23403928
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tim50 maintains the permeability barrier of the mitochondrial inner membrane.

Meinecke M, Wagner R, Kovermann P, Guiard B, Mick DU, Hutu DP, Voos W, Truscott KN, Chacinska A, Pfanner N, Rehling P.

Science. 2006 Jun 9;312(5779):1523-6.

PMID:
16763150
[PubMed - indexed for MEDLINE]
Free Article
7.

Tim50, a novel component of the TIM23 preprotein translocase of mitochondria.

Mokranjac D, Paschen SA, Kozany C, Prokisch H, Hoppins SC, Nargang FE, Neupert W, Hell K.

EMBO J. 2003 Feb 17;22(4):816-25.

PMID:
12574118
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23.

Truscott KN, Kovermann P, Geissler A, Merlin A, Meijer M, Driessen AJ, Rassow J, Pfanner N, Wagner R.

Nat Struct Biol. 2001 Dec;8(12):1074-82.

PMID:
11713477
[PubMed - indexed for MEDLINE]
9.

Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria.

Mokranjac D, Sichting M, Popov-Celeketić D, Mapa K, Gevorkyan-Airapetov L, Zohary K, Hell K, Azem A, Neupert W.

Mol Biol Cell. 2009 Mar;20(5):1400-7. doi: 10.1091/mbc.E08-09-0934. Epub 2009 Jan 14.

PMID:
19144822
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex.

Chacinska A, Rehling P, Guiard B, Frazier AE, Schulze-Specking A, Pfanner N, Voos W, Meisinger C.

EMBO J. 2003 Oct 15;22(20):5370-81.

PMID:
14532110
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Structural basis for the function of Tim50 in the mitochondrial presequence translocase.

Qian X, Gebert M, Höpker J, Yan M, Li J, Wiedemann N, van der Laan M, Pfanner N, Sha B.

J Mol Biol. 2011 Aug 19;411(3):513-9. doi: 10.1016/j.jmb.2011.06.020. Epub 2011 Jun 17.

PMID:
21704637
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase.

Hutu DP, Guiard B, Chacinska A, Becker D, Pfanner N, Rehling P, van der Laan M.

Mol Biol Cell. 2008 Jun;19(6):2642-9. doi: 10.1091/mbc.E07-12-1226. Epub 2008 Apr 9.

PMID:
18400944
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Interaction of Tim23 with Tim50 Is essential for protein translocation by the mitochondrial TIM23 complex.

Gevorkyan-Airapetov L, Zohary K, Popov-Celeketic D, Mapa K, Hell K, Neupert W, Azem A, Mokranjac D.

J Biol Chem. 2009 Feb 20;284(8):4865-72. doi: 10.1074/jbc.M807041200. Epub 2008 Nov 18.

PMID:
19017642
[PubMed - indexed for MEDLINE]
Free Article
14.

On the mechanism of preprotein import by the mitochondrial presequence translocase.

van der Laan M, Hutu DP, Rehling P.

Biochim Biophys Acta. 2010 Jun;1803(6):732-9. doi: 10.1016/j.bbamcr.2010.01.013. Epub 2010 Jan 25. Review.

PMID:
20100523
[PubMed - indexed for MEDLINE]
Free Article
15.

Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting.

Chacinska A, van der Laan M, Mehnert CS, Guiard B, Mick DU, Hutu DP, Truscott KN, Wiedemann N, Meisinger C, Pfanner N, Rehling P.

Mol Cell Biol. 2010 Jan;30(1):307-18. doi: 10.1128/MCB.00749-09. Epub .

PMID:
19884344
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

Chacinska A, Lind M, Frazier AE, Dudek J, Meisinger C, Geissler A, Sickmann A, Meyer HE, Truscott KN, Guiard B, Pfanner N, Rehling P.

Cell. 2005 Mar 25;120(6):817-29.

PMID:
15797382
[PubMed - indexed for MEDLINE]
Free Article
17.

A fluorescence assay for peptide translocation into mitochondria.

Martinez-Caballero S, Peixoto PM, Kinnally KW, Campo ML.

Anal Biochem. 2007 Mar 1;362(1):76-82. Epub 2007 Jan 22.

PMID:
17240346
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner.

Reinhold R, Krüger V, Meinecke M, Schulz C, Schmidt B, Grunau SD, Guiard B, Wiedemann N, van der Laan M, Wagner R, Rehling P, Dudek J.

Mol Cell Biol. 2012 Dec;32(24):5009-21. doi: 10.1128/MCB.00843-12. Epub 2012 Oct 8.

PMID:
23045398
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The mitochondrial import machinery: preprotein-conducting channels with binding sites for presequences.

Pfanner N, Chacinska A.

Biochim Biophys Acta. 2002 Sep 2;1592(1):15-24. Review.

PMID:
12191764
[PubMed - indexed for MEDLINE]
Free Article
20.

Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocase.

Pareek G, Krishnamoorthy V, D'Silva P.

Mol Cell Biol. 2013 Dec;33(23):4641-59. doi: 10.1128/MCB.00876-13. Epub 2013 Sep 23.

PMID:
24061477
[PubMed - indexed for MEDLINE]
Free PMC Article

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