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Results: 1 to 20 of 122

1.

FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders.

Kiyota T, Ingraham KL, Jacobsen MT, Xiong H, Ikezu T.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1339-48. doi: 10.1073/pnas.1102349108. Epub 2011 Oct 31. Erratum in: Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21282.

PMID:
22042871
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice.

Kiyota T, Ingraham KL, Swan RJ, Jacobsen MT, Andrews SJ, Ikezu T.

Gene Ther. 2012 Jul;19(7):724-33. doi: 10.1038/gt.2011.126. Epub 2011 Sep 15.

PMID:
21918553
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease.

Zhang C, McNeil E, Dressler L, Siman R.

Exp Neurol. 2007 Mar;204(1):77-87. Epub 2006 Oct 27.

PMID:
17070803
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.

Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL.

Brain. 2011 Jul;134(Pt 7):2044-56. doi: 10.1093/brain/awr133. Epub 2011 Jun 14.

PMID:
21672962
[PubMed - indexed for MEDLINE]
Free Article
5.

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.

Behav Brain Res. 2011 Sep 23;222(2):342-50. doi: 10.1016/j.bbr.2011.03.072. Epub 2011 Apr 14.

PMID:
21513747
[PubMed - indexed for MEDLINE]
6.

Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model.

Yu Y, He J, Zhang Y, Luo H, Zhu S, Yang Y, Zhao T, Wu J, Huang Y, Kong J, Tan Q, Li XM.

Hippocampus. 2009 Dec;19(12):1247-53. doi: 10.1002/hipo.20587.

PMID:
19309037
[PubMed - indexed for MEDLINE]
7.

CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.

Naert G, Rivest S.

J Neurosci. 2011 Apr 20;31(16):6208-20. doi: 10.1523/JNEUROSCI.0299-11.2011.

PMID:
21508244
[PubMed - indexed for MEDLINE]
Free Article
8.

Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease.

Biscaro B, Lindvall O, Tesco G, Ekdahl CT, Nitsch RM.

Neurodegener Dis. 2012;9(4):187-98. doi: 10.1159/000330363. Epub 2012 May 8.

PMID:
22584394
[PubMed - indexed for MEDLINE]
9.

The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease.

Hamilton A, Holscher C.

Brain Res. 2012 Apr 17;1449:83-93. doi: 10.1016/j.brainres.2012.02.015. Epub 2012 Feb 13.

PMID:
22418058
[PubMed - indexed for MEDLINE]
10.

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease.

Kanninen K, Heikkinen R, Malm T, Rolova T, Kuhmonen S, Leinonen H, Ylä-Herttuala S, Tanila H, Levonen AL, Koistinaho M, Koistinaho J.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16505-10. doi: 10.1073/pnas.0908397106. Epub 2009 Sep 10.

PMID:
19805328
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Abeta immunotherapy protects morphology and survival of adult-born neurons in doubly transgenic APP/PS1 mice.

Biscaro B, Lindvall O, Hock C, Ekdahl CT, Nitsch RM.

J Neurosci. 2009 Nov 11;29(45):14108-19. doi: 10.1523/JNEUROSCI.2055-09.2009.

PMID:
19906959
[PubMed - indexed for MEDLINE]
Free Article
12.

The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.

McClean PL, Parthsarathy V, Faivre E, Hölscher C.

J Neurosci. 2011 Apr 27;31(17):6587-94. doi: 10.1523/JNEUROSCI.0529-11.2011.

PMID:
21525299
[PubMed - indexed for MEDLINE]
Free Article
13.

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

Dewachter I, Reversé D, Caluwaerts N, Ris L, Kuipéri C, Van den Haute C, Spittaels K, Umans L, Serneels L, Thiry E, Moechars D, Mercken M, Godaux E, Van Leuven F.

J Neurosci. 2002 May 1;22(9):3445-53.

PMID:
11978821
[PubMed - indexed for MEDLINE]
Free Article
14.

Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.

Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT.

J Neurosci. 2010 Feb 17;30(7):2442-53. doi: 10.1523/JNEUROSCI.5038-09.2010.

PMID:
20164328
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic mice.

Valero J, España J, Parra-Damas A, Martín E, Rodríguez-Álvarez J, Saura CA.

PLoS One. 2011 Feb 9;6(2):e16832. doi: 10.1371/journal.pone.0016832.

PMID:
21347380
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.

Peng Y, Sun J, Hon S, Nylander AN, Xia W, Feng Y, Wang X, Lemere CA.

J Neurosci. 2010 Jun 16;30(24):8180-9. doi: 10.1523/JNEUROSCI.0340-10.2010.

PMID:
20554868
[PubMed - indexed for MEDLINE]
Free Article
17.

Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice.

Sanchez-Ramos J, Song S, Sava V, Catlow B, Lin X, Mori T, Cao C, Arendash GW.

Neuroscience. 2009 Sep 29;163(1):55-72. doi: 10.1016/j.neuroscience.2009.05.071. Epub 2009 Jun 14.

PMID:
19500657
[PubMed - indexed for MEDLINE]
18.

Intranasal delivery of plasma and platelet growth factors using PRGF-Endoret system enhances neurogenesis in a mouse model of Alzheimer's disease.

Anitua E, Pascual C, Pérez-Gonzalez R, Antequera D, Padilla S, Orive G, Carro E.

PLoS One. 2013 Sep 19;8(9):e73118. doi: 10.1371/journal.pone.0073118. eCollection 2013.

PMID:
24069173
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1ΔE9 mice.

Abbott AC, Calderon Toledo C, Aranguiz FC, Inestrosa NC, Varela-Nallar L.

J Alzheimers Dis. 2013;34(4):873-85. doi: 10.3233/JAD-121714.

PMID:
23302657
[PubMed - indexed for MEDLINE]
20.

Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.

Kimura R, Devi L, Ohno M.

J Neurochem. 2010 Apr;113(1):248-61. doi: 10.1111/j.1471-4159.2010.06608.x. Epub 2010 Jan 20.

PMID:
20089133
[PubMed - indexed for MEDLINE]
Free PMC Article

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