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Results: 1 to 20 of 169

Similar articles for PubMed (Select 22042865)

1.

Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes.

Campbell AD, Cui S, Shi L, Urbonya R, Mathias A, Bradley K, Bonsu KO, Douglas RR, Halford B, Schmidt L, Harro D, Giacherio D, Tanimoto K, Tanabe O, Engel JD.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18808-13. doi: 10.1073/pnas.1104964108. Epub 2011 Oct 31.

2.

An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer.

Tanabe O, Katsuoka F, Campbell AD, Song W, Yamamoto M, Tanimoto K, Engel JD.

EMBO J. 2002 Jul 1;21(13):3434-42.

3.

Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.

Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, Chen YT, Chang Cs, Yamamoto M, Tanimoto K, Engel JD.

EMBO J. 2007 May 2;26(9):2295-306. Epub 2007 Apr 12.

4.

Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.

Cui S, Kolodziej KE, Obara N, Amaral-Psarris A, Demmers J, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O.

Mol Cell Biol. 2011 Aug;31(16):3298-311. doi: 10.1128/MCB.05310-11. Epub 2011 Jun 13.

5.

Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.

Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM.

Invest Ophthalmol Vis Sci. 2014 May 13;55(8):5382-93. doi: 10.1167/iovs.14-14179.

6.

Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.

Xu J, Peng C, Sankaran VG, Shao Z, Esrick EB, Chong BG, Ippolito GC, Fujiwara Y, Ebert BL, Tucker PW, Orkin SH.

Science. 2011 Nov 18;334(6058):993-6. doi: 10.1126/science.1211053. Epub 2011 Oct 13.

7.

Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes.

Cui S, Tanabe O, Sierant M, Shi L, Campbell A, Lim KC, Engel JD.

Blood. 2015 Feb 26;125(9):1477-87. doi: 10.1182/blood-2014-10-605022. Epub 2015 Jan 5.

PMID:
25561507
8.

The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.

Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, Engel JD.

Genes Dev. 2007 Nov 1;21(21):2832-44.

9.

Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin.

Pestina TI, Hargrove PW, Jay D, Gray JT, Boyd KM, Persons DA.

Mol Ther. 2009 Feb;17(2):245-52. doi: 10.1038/mt.2008.259. Epub 2008 Dec 2.

10.

Second generation knockout sickle mice: the effect of HbF.

Fabry ME, Suzuka SM, Weinberg RS, Lawrence C, Factor SM, Gilman JG, Costantini F, Nagel RL.

Blood. 2001 Jan 15;97(2):410-8.

11.

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction.

Shi L, Cui S, Engel JD, Tanabe O.

Nat Med. 2013 Mar;19(3):291-4. doi: 10.1038/nm.3101. Epub 2013 Feb 17.

PMID:
23416702
12.

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.

Lettre G, Sankaran VG, Bezerra MA, Araújo AS, Uda M, Sanna S, Cao A, Schlessinger D, Costa FF, Hirschhorn JN, Orkin SH.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11869-74. doi: 10.1073/pnas.0804799105. Epub 2008 Jul 30.

14.
15.

Quantification of HBG mRNA in primary erythroid cultures: prediction of the response to hydroxyurea in sickle cell and beta-thalassemia.

Pecoraro A, Rigano P, Troia A, Calzolari R, Scazzone C, Maggio A, Steinberg MH, Di Marzo R.

Eur J Haematol. 2014 Jan;92(1):66-72. doi: 10.1111/ejh.12204. Epub 2013 Oct 22.

PMID:
24112139
16.

A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction.

Perumbeti A, Higashimoto T, Urbinati F, Franco R, Meiselman HJ, Witte D, Malik P.

Blood. 2009 Aug 6;114(6):1174-85. doi: 10.1182/blood-2009-01-201863. Epub 2009 May 27.

17.
18.

Fetal hemoglobin silencing in humans.

Oneal PA, Gantt NM, Schwartz JD, Bhanu NV, Lee YT, Moroney JW, Reed CH, Schechter AN, Luban NL, Miller JL.

Blood. 2006 Sep 15;108(6):2081-6. Epub 2006 May 30.

19.

Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.

McConnell SC, Huo Y, Liu S, Ryan TM.

Mol Cell Biol. 2011 Feb;31(4):876-83. doi: 10.1128/MCB.00725-10. Epub 2010 Dec 20.

20.

Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients.

Breda L, Casu C, Gardenghi S, Bianchi N, Cartegni L, Narla M, Yazdanbakhsh K, Musso M, Manwani D, Little J, Gardner LB, Kleinert DA, Prus E, Fibach E, Grady RW, Giardina PJ, Gambari R, Rivella S.

PLoS One. 2012;7(3):e32345. doi: 10.1371/journal.pone.0032345. Epub 2012 Mar 27.

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