Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 95

1.

Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast.

Lanthaler K, Bilsland E, Dobson PD, Moss HJ, Pir P, Kell DB, Oliver SG.

BMC Biol. 2011 Oct 24;9:70. doi: 10.1186/1741-7007-9-70.

PMID:
22023736
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

Dobson PD, Kell DB.

Nat Rev Drug Discov. 2008 Mar;7(3):205-20. doi: 10.1038/nrd2438. Review.

PMID:
18309312
[PubMed - indexed for MEDLINE]
3.

Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only.

Kell DB, Dobson PD, Oliver SG.

Drug Discov Today. 2011 Aug;16(15-16):704-14. doi: 10.1016/j.drudis.2011.05.010. Epub 2011 May 23.

PMID:
21624498
[PubMed - indexed for MEDLINE]
4.

The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so.

Kell DB, Dobson PD, Bilsland E, Oliver SG.

Drug Discov Today. 2013 Mar;18(5-6):218-39. doi: 10.1016/j.drudis.2012.11.008. Epub 2012 Nov 30.

PMID:
23207804
[PubMed - indexed for MEDLINE]
5.

Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.

PMID:
18416308
[PubMed - indexed for MEDLINE]
6.

Coexistence of passive and carrier-mediated processes in drug transport.

Sugano K, Kansy M, Artursson P, Avdeef A, Bendels S, Di L, Ecker GF, Faller B, Fischer H, Gerebtzoff G, Lennernaes H, Senner F.

Nat Rev Drug Discov. 2010 Aug;9(8):597-614. doi: 10.1038/nrd3187. Review.

PMID:
20671764
[PubMed - indexed for MEDLINE]
7.

Membrane transport as a determinant of the hepatic elimination of drugs and metabolites.

Evans AM.

Clin Exp Pharmacol Physiol. 1996 Oct-Nov;23(10-11):970-4. Review.

PMID:
8911743
[PubMed - indexed for MEDLINE]
8.

Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways.

Han S, Kim D.

PLoS Comput Biol. 2008 Aug 29;4(8):e1000162. doi: 10.1371/journal.pcbi.1000162.

PMID:
18769708
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Implications of the dominant role of transporters in drug uptake by cells.

Dobson PD, Lanthaler K, Oliver SG, Kell DB.

Curr Top Med Chem. 2009;9(2):163-81. Review.

PMID:
19200003
[PubMed - indexed for MEDLINE]
10.

From drug to protein: using yeast genetics for high-throughput target discovery.

Armour CD, Lum PY.

Curr Opin Chem Biol. 2005 Feb;9(1):20-4. Review.

PMID:
15701448
[PubMed - indexed for MEDLINE]
11.

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.

Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C.

PLoS Genet. 2008 Aug 8;4(8):e1000151. doi: 10.1371/journal.pgen.1000151.

PMID:
18688276
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome-wide analysis of membrane transport using yeast knockout arrays.

Burston HE, Davey M, Conibear E.

Methods Mol Biol. 2008;457:29-39.

PMID:
19066017
[PubMed - indexed for MEDLINE]
13.

Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake.

Yun CW, Ferea T, Rashford J, Ardon O, Brown PO, Botstein D, Kaplan J, Philpott CC.

J Biol Chem. 2000 Apr 7;275(14):10709-15.

PMID:
10744769
[PubMed - indexed for MEDLINE]
Free Article
14.

Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae.

Cai H, Kauffman S, Naider F, Becker JM.

Genetics. 2006 Mar;172(3):1459-76. Epub 2005 Dec 15.

PMID:
16361226
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Yeast genomics and drug target identification.

Bharucha N, Kumar A.

Comb Chem High Throughput Screen. 2007 Sep;10(8):618-34. Review.

PMID:
18045076
[PubMed - indexed for MEDLINE]
16.

Frog intestinal sac as an in vitro method for the assessment of intestinal permeability in humans: Application to carrier transported drugs.

Franco M, Lopedota A, Trapani A, Cutrignelli A, Meleleo D, Micelli S, Trapani G.

Int J Pharm. 2008 Mar 20;352(1-2):182-8. Epub 2007 Dec 11.

PMID:
18055143
[PubMed - indexed for MEDLINE]
17.

Identification of a novel membrane transporter associated with intracellular membranes by phenotypic complementation in the yeast Saccharomyces cerevisiae.

Hogue DL, Ellison MJ, Young JD, Cass CE.

J Biol Chem. 1996 Apr 19;271(16):9801-8.

PMID:
8621662
[PubMed - indexed for MEDLINE]
Free Article
18.

Enhanced canavanine uptake is associated with nucleotide permeability in a thymidylate auxotroph of Saccharomyces cerevisiae.

Kohalmi SE, Kunz BA.

Curr Genet. 1989 Feb;15(2):129-34.

PMID:
2663190
[PubMed - indexed for MEDLINE]
19.

Evidence-based approach to assess passive diffusion and carrier-mediated drug transport.

Di L, Artursson P, Avdeef A, Ecker GF, Faller B, Fischer H, Houston JB, Kansy M, Kerns EH, Krämer SD, Lennernäs H, Sugano K.

Drug Discov Today. 2012 Aug;17(15-16):905-12. doi: 10.1016/j.drudis.2012.03.015. Epub 2012 Apr 4. Review.

PMID:
22507594
[PubMed - indexed for MEDLINE]
20.

Localization and function of the yeast multidrug transporter Tpo1p.

Albertsen M, Bellahn I, Krämer R, Waffenschmidt S.

J Biol Chem. 2003 Apr 11;278(15):12820-5. Epub 2003 Jan 31.

PMID:
12562762
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk