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Items: 1 to 20 of 104

1.

Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding.

Lee CY, Yeh TL, Hughes BT, Espenshade PJ.

Mol Cell. 2011 Oct 21;44(2):225-34. doi: 10.1016/j.molcel.2011.08.031.

2.

Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast.

Lee CY, Stewart EV, Hughes BT, Espenshade PJ.

EMBO J. 2009 Jan 21;28(2):135-43. doi: 10.1038/emboj.2008.271.

3.

Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member.

Hughes BT, Espenshade PJ.

EMBO J. 2008 May 21;27(10):1491-501. doi: 10.1038/emboj.2008.83. Epub 2008 Apr 17.

4.

Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation.

Porter JR, Lee CY, Espenshade PJ, Iglesias PA.

Mol Biol Cell. 2012 Sep;23(18):3764-74. doi: 10.1091/mbc.E12-06-0451. Epub 2012 Jul 25.

5.

The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor.

Yeh TL, Lee CY, Amzel LM, Espenshade PJ, Bianchet MA.

Structure. 2011 Apr 13;19(4):503-14. doi: 10.1016/j.str.2011.01.017.

6.

Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis.

Brookheart RT, Lee CY, Espenshade PJ.

J Biol Chem. 2014 Jan 31;289(5):2725-35. doi: 10.1074/jbc.M113.511899. Epub 2013 Dec 10.

7.

Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast.

Hughes BT, Nwosu CC, Espenshade PJ.

J Biol Chem. 2009 Jul 31;284(31):20512-21. doi: 10.1074/jbc.M109.002436. Epub 2009 Jun 11.

8.

SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.

Hughes AL, Todd BL, Espenshade PJ.

Cell. 2005 Mar 25;120(6):831-42.

9.

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.

Koivunen P, Hirsilä M, Günzler V, Kivirikko KI, Myllyharju J.

J Biol Chem. 2004 Mar 12;279(11):9899-904. Epub 2003 Dec 29.

10.

The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen.

del Peso L, Castellanos MC, Temes E, Martin-Puig S, Cuevas Y, Olmos G, Landazuri MO.

J Biol Chem. 2003 Dec 5;278(49):48690-5. Epub 2003 Sep 23.

11.

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.

Chowdhury R, McDonough MA, Mecinović J, Loenarz C, Flashman E, Hewitson KS, Domene C, Schofield CJ.

Structure. 2009 Jul 15;17(7):981-9. doi: 10.1016/j.str.2009.06.002.

12.

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E.

Biochem J. 2004 Aug 1;381(Pt 3):761-7.

13.

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

Martin F, Linden T, Katschinski DM, Oehme F, Flamme I, Mukhopadhyay CK, Eckhardt K, Tröger J, Barth S, Camenisch G, Wenger RH.

Blood. 2005 Jun 15;105(12):4613-9. Epub 2005 Mar 1.

14.

Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast.

Kim J, Ha HJ, Kim S, Choi AR, Lee SJ, Hoe KL, Kim DU.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):606-10. doi: 10.1016/j.bbrc.2015.10.165. Epub 2015 Nov 3.

PMID:
26545776
15.

A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery.

Alcaide-German ML, Vara-Vega A, Garcia-Fernandez LF, Landazuri MO, del Peso L.

BMC Cell Biol. 2008 Apr 10;9:18. doi: 10.1186/1471-2121-9-18.

16.

The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.

Barth S, Nesper J, Hasgall PA, Wirthner R, Nytko KJ, Edlich F, Katschinski DM, Stiehl DP, Wenger RH, Camenisch G.

Mol Cell Biol. 2007 May;27(10):3758-68. Epub 2007 Mar 12.

17.

Prolyl 4-hydroxylases, master regulators of the hypoxia response.

Myllyharju J.

Acta Physiol (Oxf). 2013 Jun;208(2):148-65. doi: 10.1111/apha.12096. Epub 2013 Apr 12. Review.

PMID:
23489300
18.

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.

D'Angelo G, Duplan E, Boyer N, Vigne P, Frelin C.

J Biol Chem. 2003 Oct 3;278(40):38183-7. Epub 2003 Jul 21.

19.

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL.

Mol Cell. 2005 Feb 18;17(4):503-12.

20.

Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites.

Pappalardi MB, McNulty DE, Martin JD, Fisher KE, Jiang Y, Burns MC, Zhao H, Ho T, Sweitzer S, Schwartz B, Annan RS, Copeland RA, Tummino PJ, Luo L.

Biochem J. 2011 Jun 1;436(2):363-9. doi: 10.1042/BJ20101201.

PMID:
21410436
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