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Results: 1 to 20 of 95

1.

Convergence of the insulin and serotonin programs in the pancreatic β-cell.

Ohta Y, Kosaka Y, Kishimoto N, Wang J, Smith SB, Honig G, Kim H, Gasa RM, Neubauer N, Liou A, Tecott LH, Deneris ES, German MS.

Diabetes. 2011 Dec;60(12):3208-16. doi: 10.2337/db10-1192. Epub 2011 Oct 19.

PMID:
22013016
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic β-cell proliferation and the expression of insulin regulators.

Shi K, Parekh VI, Roy S, Desai SS, Agarwal SK.

Endocr Relat Cancer. 2013 Feb 18;20(1):111-22. doi: 10.1530/ERC-12-0077. Print 2013 Feb.

PMID:
23419452
[PubMed - indexed for MEDLINE]
Free Article
3.

Forced expression of LIM homeodomain transcription factor 1b enhances differentiation of mouse embryonic stem cells into serotonergic neurons.

Dolmazon V, Alenina N, Markossian S, Mancip J, van de Vrede Y, Fontaine E, Dehay C, Kennedy H, Bader M, Savatier P, Bernat A.

Stem Cells Dev. 2011 Feb;20(2):301-11. doi: 10.1089/scd.2010.0224. Epub 2010 Oct 12.

PMID:
20649486
[PubMed - indexed for MEDLINE]
4.

The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1.

Iype T, Taylor DG, Ziesmann SM, Garmey JC, Watada H, Mirmira RG.

Mol Endocrinol. 2004 Jun;18(6):1363-75. Epub 2004 Mar 31.

PMID:
15056733
[PubMed - indexed for MEDLINE]
5.
6.

Lmx1b, Pet-1, and Nkx2.2 coordinately specify serotonergic neurotransmitter phenotype.

Cheng L, Chen CL, Luo P, Tan M, Qiu M, Johnson R, Ma Q.

J Neurosci. 2003 Nov 5;23(31):9961-7.

PMID:
14602809
[PubMed - indexed for MEDLINE]
Free Article
7.

Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos.

Teraoka H, Russell C, Regan J, Chandrasekhar A, Concha ML, Yokoyama R, Higashi K, Take-Uchi M, Dong W, Hiraga T, Holder N, Wilson SW.

J Neurobiol. 2004 Sep 5;60(3):275-88.

PMID:
15281067
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development.

Smith SB, Ee HC, Conners JR, German MS.

Mol Cell Biol. 1999 Dec;19(12):8272-80.

PMID:
10567552
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells.

Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS.

Development. 1998 Jun;125(12):2213-21.

PMID:
9584121
[PubMed - indexed for MEDLINE]
Free Article
10.

Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription.

Francis J, Chakrabarti SK, Garmey JC, Mirmira RG.

J Biol Chem. 2005 Oct 28;280(43):36244-53. Epub 2005 Sep 1.

PMID:
16141209
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas.

Van Velkinburgh JC, Samaras SE, Gerrish K, Artner I, Stein R.

J Biol Chem. 2005 Nov 18;280(46):38438-44. Epub 2005 Sep 7.

PMID:
16147997
[PubMed - indexed for MEDLINE]
Free Article
12.

Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas.

Lima MJ, Docherty HM, Chen Y, Vallier L, Docherty K.

PLoS One. 2012;7(5):e36481. doi: 10.1371/journal.pone.0036481. Epub 2012 May 1.

PMID:
22563503
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.

Schisler JC, Fueger PT, Babu DA, Hohmeier HE, Tessem JS, Lu D, Becker TC, Naziruddin B, Levy M, Mirmira RG, Newgard CB.

Mol Cell Biol. 2008 May;28(10):3465-76. doi: 10.1128/MCB.01791-07. Epub 2008 Mar 17.

PMID:
18347054
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Signals from the neural crest regulate beta-cell mass in the pancreas.

Nekrep N, Wang J, Miyatsuka T, German MS.

Development. 2008 Jun;135(12):2151-60. doi: 10.1242/dev.015859.

PMID:
18506029
[PubMed - indexed for MEDLINE]
Free Article
15.

Alx3-deficient mice exhibit decreased insulin in beta cells, altered glucose homeostasis and increased apoptosis in pancreatic islets.

Mirasierra M, Fernández-Pérez A, Díaz-Prieto N, Vallejo M.

Diabetologia. 2011 Feb;54(2):403-14. doi: 10.1007/s00125-010-1975-6. Epub 2010 Nov 21.

PMID:
21104068
[PubMed - indexed for MEDLINE]
16.

Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.

Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K.

Stem Cells. 2009 Feb;27(2):341-51. doi: 10.1634/stemcells.2008-0310.

PMID:
19056911
[PubMed - indexed for MEDLINE]
Free Article
17.

Distinct regulation of hepatic nuclear factor 1alpha by NKX6.1 in pancreatic beta cells.

Donelan W, Koya V, Li SW, Yang LJ.

J Biol Chem. 2010 Apr 16;285(16):12181-9. doi: 10.1074/jbc.M109.064238. Epub 2010 Jan 27.

PMID:
20106981
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes.

Deering TG, Ogihara T, Trace AP, Maier B, Mirmira RG.

Diabetes. 2009 Jan;58(1):185-93. doi: 10.2337/db08-1150. Epub 2008 Nov 4.

PMID:
18984737
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Zinc finger homeobox is required for the differentiation of serotonergic neurons in the sea urchin embryo.

Yaguchi J, Angerer LM, Inaba K, Yaguchi S.

Dev Biol. 2012 Mar 1;363(1):74-83. doi: 10.1016/j.ydbio.2011.12.024. Epub 2011 Dec 22.

PMID:
22210002
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas developmental pathway upon genetic and/or microenvironmental manipulation in vitro.

Moriscot C, de Fraipont F, Richard MJ, Marchand M, Savatier P, Bosco D, Favrot M, Benhamou PY.

Stem Cells. 2005 Apr;23(4):594-603.

PMID:
15790780
[PubMed - indexed for MEDLINE]
Free Article

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