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Results: 1 to 20 of 95

1.

The crystal structure of a Munc13 C-terminal module exhibits a remarkable similarity to vesicle tethering factors.

Li W, Ma C, Guan R, Xu Y, Tomchick DR, Rizo J.

Structure. 2011 Oct 12;19(10):1443-55. doi: 10.1016/j.str.2011.07.012.

PMID:
22000513
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex.

Ma C, Li W, Xu Y, Rizo J.

Nat Struct Mol Biol. 2011 May;18(5):542-9. doi: 10.1038/nsmb.2047. Epub 2011 Apr 17.

PMID:
21499244
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes.

Guan R, Dai H, Rizo J.

Biochemistry. 2008 Feb 12;47(6):1474-81. doi: 10.1021/bi702345m. Epub 2008 Jan 18.

PMID:
18201107
[PubMed - indexed for MEDLINE]
4.

Remote homology between Munc13 MUN domain and vesicle tethering complexes.

Pei J, Ma C, Rizo J, Grishin NV.

J Mol Biol. 2009 Aug 21;391(3):509-17. doi: 10.1016/j.jmb.2009.06.054. Epub 2009 Jun 27.

PMID:
19563813
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog.

Misura KM, Bock JB, Gonzalez LC Jr, Scheller RH, Weis WI.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9184-9. Epub 2002 Jun 24.

PMID:
12082176
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin.

Betz A, Okamoto M, Benseler F, Brose N.

J Biol Chem. 1997 Jan 24;272(4):2520-6.

PMID:
8999968
[PubMed - indexed for MEDLINE]
Free Article
7.

The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.

Bracher A, Perrakis A, Dresbach T, Betz H, Weissenhorn W.

Structure. 2000 Jul 15;8(7):685-94.

PMID:
10903948
[PubMed - indexed for MEDLINE]
8.

Novel interactions of CAPS (Ca2+-dependent activator protein for secretion) with the three neuronal SNARE proteins required for vesicle fusion.

Daily NJ, Boswell KL, James DJ, Martin TF.

J Biol Chem. 2010 Nov 12;285(46):35320-9. doi: 10.1074/jbc.M110.145169. Epub 2010 Sep 8.

PMID:
20826818
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

Basu J, Betz A, Brose N, Rosenmund C.

J Neurosci. 2007 Jan 31;27(5):1200-10.

PMID:
17267576
[PubMed - indexed for MEDLINE]
Free Article
10.

Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.

Nguyen Truong CQ, Nestvogel D, Ratai O, Schirra C, Stevens DR, Brose N, Rhee J, Rettig J.

Cell Rep. 2014 Nov 6;9(3):902-9. doi: 10.1016/j.celrep.2014.09.050. Epub 2014 Oct 23.

PMID:
25437547
[PubMed - in process]
Free Article
11.

Reluctance to membrane binding enables accessibility of the synaptobrevin SNARE motif for SNARE complex formation.

Brewer KD, Li W, Horne BE, Rizo J.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12723-8. doi: 10.1073/pnas.1105128108. Epub 2011 Jul 18.

PMID:
21768342
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex.

Rathore SS, Bend EG, Yu H, Hammarlund M, Jorgensen EM, Shen J.

Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22399-406. doi: 10.1073/pnas.1012997108. Epub 2010 Dec 7.

PMID:
21139055
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

Hayashi T, Yamasaki S, Nauenburg S, Binz T, Niemann H.

EMBO J. 1995 May 15;14(10):2317-25.

PMID:
7774590
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution.

Sutton RB, Fasshauer D, Jahn R, Brunger AT.

Nature. 1998 Sep 24;395(6700):347-53.

PMID:
9759724
[PubMed - indexed for MEDLINE]
15.

SNARE proteins: one to fuse and three to keep the nascent fusion pore open.

Shi L, Shen QT, Kiel A, Wang J, Wang HW, Melia TJ, Rothman JE, Pincet F.

Science. 2012 Mar 16;335(6074):1355-9. doi: 10.1126/science.1214984.

PMID:
22422984
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.

Parisotto D, Pfau M, Scheutzow A, Wild K, Mayer MP, Malsam J, Sinning I, Söllner TH.

J Biol Chem. 2014 Apr 4;289(14):9639-50. doi: 10.1074/jbc.M113.514273. Epub 2014 Feb 14.

PMID:
24532794
[PubMed - indexed for MEDLINE]
17.

Structural basis for the inhibitory role of tomosyn in exocytosis.

Pobbati AV, Razeto A, Böddener M, Becker S, Fasshauer D.

J Biol Chem. 2004 Nov 5;279(45):47192-200. Epub 2004 Aug 16.

PMID:
15316007
[PubMed - indexed for MEDLINE]
Free Article
18.

Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch.

Lu J, Machius M, Dulubova I, Dai H, Südhof TC, Tomchick DR, Rizo J.

PLoS Biol. 2006 Jul;4(7):e192.

PMID:
16732694
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion.

Krishnakumar SS, Radoff DT, Kümmel D, Giraudo CG, Li F, Khandan L, Baguley SW, Coleman J, Reinisch KM, Pincet F, Rothman JE.

Nat Struct Mol Biol. 2011 Jul 24;18(8):934-40. doi: 10.1038/nsmb.2103.

PMID:
21785412
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex.

Misura KM, Scheller RH, Weis WI.

Nature. 2000 Mar 23;404(6776):355-62.

PMID:
10746715
[PubMed - indexed for MEDLINE]
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