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Items: 1 to 20 of 109

1.

Biophysical analysis of binding of WW domains of the YAP2 transcriptional regulator to PPXY motifs within WBP1 and WBP2 adaptors.

McDonald CB, McIntosh SK, Mikles DC, Bhat V, Deegan BJ, Seldeen KL, Saeed AM, Buffa L, Sudol M, Nawaz Z, Farooq A.

Biochemistry. 2011 Nov 8;50(44):9616-27. doi: 10.1021/bi201286p. Epub 2011 Oct 14.

2.

Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptors.

McDonald CB, Buffa L, Bar-Mag T, Salah Z, Bhat V, Mikles DC, Deegan BJ, Seldeen KL, Malhotra A, Sudol M, Aqeilan RI, Nawaz Z, Farooq A.

J Mol Biol. 2012 Sep 7;422(1):58-74. doi: 10.1016/j.jmb.2012.05.015. Epub 2012 May 23.

3.

Molecular basis of the binding of YAP transcriptional regulator to the ErbB4 receptor tyrosine kinase.

Schuchardt BJ, Bhat V, Mikles DC, McDonald CB, Sudol M, Farooq A.

Biochimie. 2014 Jun;101:192-202. doi: 10.1016/j.biochi.2014.01.011. Epub 2014 Jan 25.

4.

Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity.

Schuchardt BJ, Mikles DC, Hoang LM, Bhat V, McDonald CB, Sudol M, Farooq A.

FEBS J. 2014 Dec;281(24):5532-51. doi: 10.1111/febs.13095. Epub 2014 Nov 4.

5.

Molecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase.

Schuchardt BJ, Bhat V, Mikles DC, McDonald CB, Sudol M, Farooq A.

Biochemistry. 2013 Dec 23;52(51):9223-36. doi: 10.1021/bi400987k. Epub 2013 Dec 13.

6.

Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway.

Webb C, Upadhyay A, Giuntini F, Eggleston I, Furutani-Seiki M, Ishima R, Bagby S.

Biochemistry. 2011 Apr 26;50(16):3300-9. doi: 10.1021/bi2001888. Epub 2011 Mar 31.

PMID:
21417403
7.

WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ.

Chan SW, Lim CJ, Huang C, Chong YF, Gunaratne HJ, Hogue KA, Blackstock WP, Harvey KF, Hong W.

Oncogene. 2011 Feb 3;30(5):600-10. doi: 10.1038/onc.2010.438. Epub 2010 Oct 25.

8.

WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands.

Iglesias-Bexiga M, Castillo F, Cobos ES, Oka T, Sudol M, Luque I.

PLoS One. 2015 Jan 21;10(1):e0113828. doi: 10.1371/journal.pone.0113828. eCollection 2015.

9.

Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif.

Oka T, Sudol M.

Genes Cells. 2009 May;14(5):607-15. doi: 10.1111/j.1365-2443.2009.01292.x. Epub 2009 Apr 15.

11.

Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch.

Schuchardt BJ, Mikles DC, Bhat V, McDonald CB, Sudol M, Farooq A.

J Mol Recognit. 2015 Apr;28(4):220-31. doi: 10.1002/jmr.2419. Epub 2015 Feb 19.

12.
13.

Molecular interaction between Smurf1 WW2 domain and PPXY motifs of Smad1, Smad5, and Smad6--modeling and analysis.

Sangadala S, Metpally RP, Reddy BV.

J Biomol Struct Dyn. 2007 Aug;25(1):11-23.

PMID:
17676934
14.

Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands.

Chen HI, Einbond A, Kwak SJ, Linn H, Koepf E, Peterson S, Kelly JW, Sudol M.

J Biol Chem. 1997 Jul 4;272(27):17070-7.

15.

Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domains.

Mosser EA, Kasanov JD, Forsberg EC, Kay BK, Ney PA, Bresnick EH.

Biochemistry. 1998 Sep 29;37(39):13686-95.

PMID:
9753456
16.

Multivalent binding of formin-binding protein 21 (FBP21)-tandem-WW domains fosters protein recognition in the pre-spliceosome.

Klippel S, Wieczorek M, Schümann M, Krause E, Marg B, Seidel T, Meyer T, Knapp EW, Freund C.

J Biol Chem. 2011 Nov 4;286(44):38478-87. doi: 10.1074/jbc.M111.265710. Epub 2011 Sep 14.

17.

Binding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms.

McDonald CB, Seldeen KL, Deegan BJ, Bhat V, Farooq A.

J Mol Recognit. 2011 Jul-Aug;24(4):585-96. doi: 10.1002/jmr.1080. Epub 2010 Dec 13.

18.
19.

WW or WoW: the WW domains in a union of bliss.

Sudol M, Recinos CC, Abraczinskas J, Humbert J, Farooq A.

IUBMB Life. 2005 Dec;57(12):773-8. Review.

20.

Using molecular repertoires to identify high-affinity peptide ligands of the WW domain of human and mouse YAP.

Linn H, Ermekova KS, Rentschler S, Sparks AB, Kay BK, Sudol M.

Biol Chem. 1997 Jun;378(6):531-7.

PMID:
9224934
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