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Results: 1 to 20 of 67

1.

NOTCH Signaling and ATOH1 in Colorectal Cancers.

Kazanjian A, Shroyer NF.

Curr Colorectal Cancer Rep. 2011 Jun;7(2):121-127.

PMID:
21980310
[PubMed]
Free PMC Article
2.

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells.

Kazanjian A, Noah T, Brown D, Burkart J, Shroyer NF.

Gastroenterology. 2010 Sep;139(3):918-28, 928.e1-6. doi: 10.1053/j.gastro.2010.05.081. Epub 2010 Jun 2.

PMID:
20621629
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus.

Tamagawa Y, Ishimura N, Uno G, Yuki T, Kazumori H, Ishihara S, Amano Y, Kinoshita Y.

Lab Invest. 2012 Jun;92(6):896-909. doi: 10.1038/labinvest.2012.56. Epub 2012 Mar 26.

PMID:
22449796
[PubMed - indexed for MEDLINE]
Free Article
4.

Suppression of hath1 gene expression directly regulated by hes1 via notch signaling is associated with goblet cell depletion in ulcerative colitis.

Zheng X, Tsuchiya K, Okamoto R, Iwasaki M, Kano Y, Sakamoto N, Nakamura T, Watanabe M.

Inflamm Bowel Dis. 2011 Nov;17(11):2251-60. doi: 10.1002/ibd.21611. Epub 2011 Jan 6.

PMID:
21987298
[PubMed - indexed for MEDLINE]
5.

Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation.

Li HJ, Ray SK, Singh NK, Johnston B, Leiter AB.

Diabetes Obes Metab. 2011 Oct;13 Suppl 1:5-12. doi: 10.1111/j.1463-1326.2011.01438.x. Review.

PMID:
21824251
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal homolog 1 (ATOH1, HATH1, MATH1) in neuroendocrine tumors.

Westerman BA, Breuer RH, Poutsma A, Chhatta A, Noorduyn LA, Koolen MG, Postmus PE, Blankenstein MA, Oudejans CB.

Int J Biol Markers. 2007 Apr-Jun;22(2):114-23.

PMID:
17549667
[PubMed - indexed for MEDLINE]
7.

Numb modulates intestinal epithelial cells toward goblet cell phenotype by inhibiting the Notch signaling pathway.

Yang Y, Zhu R, Bai J, Zhang X, Tian Y, Li X, Peng Z, He Y, Chen L, Ji Q, Chen W, Fang D, Wang R.

Exp Cell Res. 2011 Jul 1;317(11):1640-8. doi: 10.1016/j.yexcr.2011.04.008. Epub 2011 Apr 30.

PMID:
21557937
[PubMed - indexed for MEDLINE]
8.

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY.

Science. 2001 Dec 7;294(5549):2155-8.

PMID:
11739954
[PubMed - indexed for MEDLINE]
Free Article
9.

Atonal homolog 1 is a tumor suppressor gene.

Bossuyt W, Kazanjian A, De Geest N, Van Kelst S, De Hertogh G, Geboes K, Boivin GP, Luciani J, Fuks F, Chuah M, VandenDriessche T, Marynen P, Cools J, Shroyer NF, Hassan BA.

PLoS Biol. 2009 Feb 24;7(2):e39. doi: 10.1371/journal.pbio.1000039.

PMID:
19243219
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors.

van Es JH, de Geest N, van de Born M, Clevers H, Hassan BA.

Nat Commun. 2010 May 17;1:18. doi: 10.1038/ncomms1017.

PMID:
20975679
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Origin of the brush cell lineage in the mouse intestinal epithelium.

Bjerknes M, Khandanpour C, Möröy T, Fujiyama T, Hoshino M, Klisch TJ, Ding Q, Gan L, Wang J, Martín MG, Cheng H.

Dev Biol. 2012 Feb 15;362(2):194-218. doi: 10.1016/j.ydbio.2011.12.009. Epub 2011 Dec 13.

PMID:
22185794
[PubMed - indexed for MEDLINE]
Free Article
12.

Minireview: Development and differentiation of gut endocrine cells.

Schonhoff SE, Giel-Moloney M, Leiter AB.

Endocrinology. 2004 Jun;145(6):2639-44. Epub 2004 Mar 24. Review.

PMID:
15044355
[PubMed - indexed for MEDLINE]
13.

Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis.

Shroyer NF, Helmrath MA, Wang VY, Antalffy B, Henning SJ, Zoghbi HY.

Gastroenterology. 2007 Jun;132(7):2478-88. Epub 2007 Mar 24.

PMID:
17570220
[PubMed - indexed for MEDLINE]
14.

Notch in the intestine: regulation of homeostasis and pathogenesis.

Noah TK, Shroyer NF.

Annu Rev Physiol. 2013;75:263-88. doi: 10.1146/annurev-physiol-030212-183741. Epub 2012 Nov 26. Review.

PMID:
23190077
[PubMed - indexed for MEDLINE]
15.

The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1.

Mutoh H, Sakamoto H, Hayakawa H, Arao Y, Satoh K, Nokubi M, Sugano K.

Differentiation. 2006 Jul;74(6):313-21.

PMID:
16831200
[PubMed - indexed for MEDLINE]
16.

A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma.

Leow CC, Polakis P, Gao WQ.

Ann N Y Acad Sci. 2005 Nov;1059:174-83. Review.

PMID:
16382053
[PubMed - indexed for MEDLINE]
17.

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.

Milano J, McKay J, Dagenais C, Foster-Brown L, Pognan F, Gadient R, Jacobs RT, Zacco A, Greenberg B, Ciaccio PJ.

Toxicol Sci. 2004 Nov;82(1):341-58. Epub 2004 Aug 19.

PMID:
15319485
[PubMed - indexed for MEDLINE]
Free Article
18.

Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.

Akiyama J, Okamoto R, Iwasaki M, Zheng X, Yui S, Tsuchiya K, Nakamura T, Watanabe M.

Biochem Biophys Res Commun. 2010 Mar 19;393(4):662-7. doi: 10.1016/j.bbrc.2010.02.048. Epub 2010 Feb 17.

PMID:
20170633
[PubMed - indexed for MEDLINE]
19.

Beta-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3' enhancer.

Shi F, Cheng YF, Wang XL, Edge AS.

J Biol Chem. 2010 Jan 1;285(1):392-400. doi: 10.1074/jbc.M109.059055. Epub 2009 Oct 28.

PMID:
19864427
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Hath1 up-regulates gastric mucin gene expression in gastric cells.

Sekine A, Akiyama Y, Yanagihara K, Yuasa Y.

Biochem Biophys Res Commun. 2006 Jun 16;344(4):1166-71. Epub 2006 Apr 21.

PMID:
16647036
[PubMed - indexed for MEDLINE]

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