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Results: 1 to 20 of 86

1.

T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion.

Tyrberg B, Miles P, Azizian KT, Denzel MS, Nieves ML, Monosov EZ, Levine F, Ranscht B.

Islets. 2011 Nov-Dec;3(6):327-37. doi: 10.4161/isl.3.6.17705. Epub 2011 Nov 1.

PMID:
21975561
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

CaV2.3 calcium channels control second-phase insulin release.

Jing X, Li DQ, Olofsson CS, Salehi A, Surve VV, Caballero J, Ivarsson R, Lundquist I, Pereverzev A, Schneider T, Rorsman P, Renström E.

J Clin Invest. 2005 Jan;115(1):146-54.

PMID:
15630454
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion.

Geng X, Lou H, Wang J, Li L, Swanson AL, Sun M, Beers-Stolz D, Watkins S, Perez RG, Drain P.

Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E276-86. doi: 10.1152/ajpendo.00262.2010. Epub 2010 Sep 21.

PMID:
20858756
[PubMed - indexed for MEDLINE]
Free Article
4.

Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.

PMID:
16377800
[PubMed - indexed for MEDLINE]
Free Article
5.

Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion.

Robson-Doucette CA, Sultan S, Allister EM, Wikstrom JD, Koshkin V, Bhattacharjee A, Prentice KJ, Sereda SB, Shirihai OS, Wheeler MB.

Diabetes. 2011 Nov;60(11):2710-9. doi: 10.2337/db11-0132. Epub 2011 Oct 7.

PMID:
21984579
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion.

Pappan KL, Pan Z, Kwon G, Marshall CA, Coleman T, Goldberg IJ, McDaniel ML, Semenkovich CF.

J Biol Chem. 2005 Mar 11;280(10):9023-9. Epub 2005 Jan 6.

PMID:
15637076
[PubMed - indexed for MEDLINE]
Free Article
7.

Impaired insulin secretion in vivo but enhanced insulin secretion from isolated islets in pancreatic beta cell-specific vascular endothelial growth factor-A knock-out mice.

Iwashita N, Uchida T, Choi JB, Azuma K, Ogihara T, Ferrara N, Gerber H, Kawamori R, Inoue M, Watada H.

Diabetologia. 2007 Feb;50(2):380-9. Epub 2006 Dec 16.

PMID:
17180351
[PubMed - indexed for MEDLINE]
8.

Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.

Yamagata K, Nammo T, Moriwaki M, Ihara A, Iizuka K, Yang Q, Satoh T, Li M, Uenaka R, Okita K, Iwahashi H, Zhu Q, Cao Y, Imagawa A, Tochino Y, Hanafusa T, Miyagawa J, Matsuzawa Y.

Diabetes. 2002 Jan;51(1):114-23.

PMID:
11756330
[PubMed - indexed for MEDLINE]
Free Article
9.

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

Henquin JC, Nenquin M, Szollosi A, Kubosaki A, Notkins AL.

J Endocrinol. 2008 Mar;196(3):573-81. doi: 10.1677/JOE-07-0496.

PMID:
18310453
[PubMed - indexed for MEDLINE]
Free Article
10.

GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice.

Bonaventura MM, Catalano PN, Chamson-Reig A, Arany E, Hill D, Bettler B, Saravia F, Libertun C, Lux-Lantos VA.

Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E157-67. Epub 2007 Oct 30.

PMID:
17971510
[PubMed - indexed for MEDLINE]
Free Article
11.

Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

Matsumura K, Chang BH, Fujimiya M, Chen W, Kulkarni RN, Eguchi Y, Kimura H, Kojima H, Chan L.

Mol Cell Biol. 2007 Sep;27(17):6026-37. Epub 2007 Jun 18. Erratum in: Mol Cell Biol. 2007 Oct;27(20):7354.

PMID:
17576812
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Defective secretion of islet hormones in chromogranin-B deficient mice.

Obermüller S, Calegari F, King A, Lindqvist A, Lundquist I, Salehi A, Francolini M, Rosa P, Rorsman P, Huttner WB, Barg S.

PLoS One. 2010 Jan 28;5(1):e8936. doi: 10.1371/journal.pone.0008936.

PMID:
20126668
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.

Sun G, Tarasov AI, McGinty JA, French PM, McDonald A, Leclerc I, Rutter GA.

Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1261-73. doi: 10.1152/ajpendo.00100.2010. Epub 2010 Mar 30.

PMID:
20354156
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Loss of β-arrestin2 mediates pancreatic-islet dysfunction in mice.

Zhang M, Zhu Y, Mu K, Li L, Lu J, Zhao J, Huang X, Wang C, Jia W.

Biochem Biophys Res Commun. 2013 Jun 7;435(3):345-9. doi: 10.1016/j.bbrc.2013.04.079. Epub 2013 May 6.

PMID:
23660189
[PubMed - indexed for MEDLINE]
15.

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

Wijesekara N, Dai FF, Hardy AB, Giglou PR, Bhattacharjee A, Koshkin V, Chimienti F, Gaisano HY, Rutter GA, Wheeler MB.

Diabetologia. 2010 Aug;53(8):1656-68. doi: 10.1007/s00125-010-1733-9. Epub 2010 Apr 28.

PMID:
20424817
[PubMed - indexed for MEDLINE]
16.

CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight.

Wierup N, Richards WG, Bannon AW, Kuhar MJ, Ahrén B, Sundler F.

Regul Pept. 2005 Jul 15;129(1-3):203-11.

PMID:
15927717
[PubMed - indexed for MEDLINE]
17.

[Impact of islet alpha cell loss on insulin secretion].

Li G, Ye L, Li J, Yang W, Lou J.

Zhonghua Yi Xue Za Zhi. 2002 Oct 25;82(20):1427-31. Chinese.

PMID:
12509929
[PubMed - indexed for MEDLINE]
18.

Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice.

Peterhoff M, Sieg A, Brede M, Chao CM, Hein L, Ullrich S.

Eur J Endocrinol. 2003 Oct;149(4):343-50.

PMID:
14514350
[PubMed - indexed for MEDLINE]
Free Article
19.

The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets.

Li XN, Herrington J, Petrov A, Ge L, Eiermann G, Xiong Y, Jensen MV, Hohmeier HE, Newgard CB, Garcia ML, Wagner M, Zhang BB, Thornberry NA, Howard AD, Kaczorowski GJ, Zhou YP.

J Pharmacol Exp Ther. 2013 Feb;344(2):407-16. doi: 10.1124/jpet.112.199083. Epub 2012 Nov 16.

PMID:
23161216
[PubMed - indexed for MEDLINE]
Free Article
20.

Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic islets.

Jabs N, Franklin I, Brenner MB, Gromada J, Ferrara N, Wollheim CB, Lammert E.

Exp Clin Endocrinol Diabetes. 2008 Sep;116 Suppl 1:S46-9. doi: 10.1055/s-2008-1081486. Epub 2008 Sep 5.

PMID:
18777454
[PubMed - indexed for MEDLINE]

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