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Results: 1 to 20 of 152

1.

Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer.

Husain K, Francois RA, Yamauchi T, Perez M, Sebti SM, Malafa MP.

Mol Cancer Ther. 2011 Dec;10(12):2363-72. doi: 10.1158/1535-7163.MCT-11-0424. Epub 2011 Oct 4.

PMID:
21971120
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo.

Wang YW, Wang SJ, Zhou YN, Pan SH, Sun B.

J Cancer Res Clin Oncol. 2012 May;138(5):785-97. doi: 10.1007/s00432-012-1152-z. Epub 2012 Jan 24.

PMID:
22270965
[PubMed - indexed for MEDLINE]
3.

Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.

Banerjee S, Zhang Y, Ali S, Bhuiyan M, Wang Z, Chiao PJ, Philip PA, Abbruzzese J, Sarkar FH.

Cancer Res. 2005 Oct 1;65(19):9064-72.

PMID:
16204081
[PubMed - indexed for MEDLINE]
Free Article
4.
5.

{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.

Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Yadav VR, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB.

Cancer Res. 2010 Nov 1;70(21):8695-705. doi: 10.1158/0008-5472.CAN-10-2318. Epub 2010 Sep 23.

PMID:
20864511
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.

Manu KA, Shanmugam MK, Ramachandran L, Li F, Fong CW, Kumar AP, Tan P, Sethi G.

Clin Cancer Res. 2012 Apr 15;18(8):2220-9. doi: 10.1158/1078-0432.CCR-11-2470. Epub 2012 Feb 20.

PMID:
22351692
[PubMed - indexed for MEDLINE]
Free Article
7.

Enhanced antitumor efficacy by the combination of emodin and gemcitabine against human pancreatic cancer cells via downregulation of the expression of XIAP in vitro and in vivo.

Wang ZH, Chen H, Guo HC, Tong HF, Liu JX, Wei WT, Tan W, Ni ZL, Liu HB, Lin SZ.

Int J Oncol. 2011 Nov;39(5):1123-31. doi: 10.3892/ijo.2011.1115. Epub 2011 Jul 6.

PMID:
21743963
[PubMed - indexed for MEDLINE]
8.

Emodin potentiates the antitumor effects of gemcitabine in PANC-1 pancreatic cancer xenograft model in vivo via inhibition of inhibitors of apoptosis.

Guo HC, Bu HQ, Luo J, Wei WT, Liu DL, Chen H, Tong HF, Wang ZH, Wu HY, Li HH, Zuo MM, Li W, Lin SZ.

Int J Oncol. 2012 Jun;40(6):1849-57. doi: 10.3892/ijo.2012.1389. Epub 2012 Feb 29.

PMID:
22378302
[PubMed - indexed for MEDLINE]
9.

Shikonin suppresses tumor growth and synergizes with gemcitabine in a pancreatic cancer xenograft model: Involvement of NF-κB signaling pathway.

Wang Y, Zhou Y, Jia G, Han B, Liu J, Teng Y, Lv J, Song Z, Li Y, Ji L, Pan S, Jiang H, Sun B.

Biochem Pharmacol. 2014 Apr 1;88(3):322-33. doi: 10.1016/j.bcp.2014.01.041. Epub 2014 Feb 9.

PMID:
24522113
[PubMed - indexed for MEDLINE]
10.

Concurrent inhibition of NF-kappaB, cyclooxygenase-2, and epidermal growth factor receptor leads to greater anti-tumor activity in pancreatic cancer.

Ali S, Banerjee S, Schaffert JM, El-Rayes BF, Philip PA, Sarkar FH.

J Cell Biochem. 2010 May;110(1):171-81. doi: 10.1002/jcb.22523.

PMID:
20213764
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Antitumor activity of gemcitabine can be potentiated in pancreatic cancer through modulation of TLR4/NF-κB signaling by 6-shogaol.

Zhou L, Qi L, Jiang L, Zhou P, Ma J, Xu X, Li P.

AAPS J. 2014 Mar;16(2):246-57. doi: 10.1208/s12248-013-9558-3. Epub 2014 Jan 15.

PMID:
24424498
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Antitumor activity of gemcitabine and oxaliplatin is augmented by thymoquinone in pancreatic cancer.

Banerjee S, Kaseb AO, Wang Z, Kong D, Mohammad M, Padhye S, Sarkar FH, Mohammad RM.

Cancer Res. 2009 Jul 1;69(13):5575-83. doi: 10.1158/0008-5472.CAN-08-4235. Epub 2009 Jun 23.

PMID:
19549912
[PubMed - indexed for MEDLINE]
Free Article
13.

Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB.

Liu A, Chen H, Tong H, Ye S, Qiu M, Wang Z, Tan W, Liu J, Lin S.

Mol Med Rep. 2011 Mar-Apr;4(2):221-7. doi: 10.3892/mmr.2011.414. Epub 2011 Jan 3.

PMID:
21468555
[PubMed - indexed for MEDLINE]
14.

Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo.

Wang SJ, Gao Y, Chen H, Kong R, Jiang HC, Pan SH, Xue DB, Bai XW, Sun B.

Cancer Lett. 2010 Jul 1;293(1):99-108. doi: 10.1016/j.canlet.2010.01.001. Epub 2010 Feb 4.

PMID:
20137856
[PubMed - indexed for MEDLINE]
15.

The C-terminal region of Bfl-1 sensitizes non-small cell lung cancer to gemcitabine-induced apoptosis by suppressing NF-κB activity and down-regulating Bfl-1.

Kim MK, Jeon YK, Woo JK, Choi Y, Choi DH, Kim YH, Kim CW.

Mol Cancer. 2011 Aug 16;10:98. doi: 10.1186/1476-4598-10-98.

PMID:
21843371
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Cisplatin-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts.

Mohammad RM, Banerjee S, Li Y, Aboukameel A, Kucuk O, Sarkar FH.

Cancer. 2006 Mar 15;106(6):1260-8.

PMID:
16475211
[PubMed - indexed for MEDLINE]
Free Article
17.

Enhanced antitumor effect of combination therapy with gemcitabine and guggulsterone in pancreatic cancer.

Ahn DW, Seo JK, Lee SH, Hwang JH, Lee JK, Ryu JK, Kim YT, Yoon YB.

Pancreas. 2012 Oct;41(7):1048-57. doi: 10.1097/MPA.0b013e318249d62e.

PMID:
22513291
[PubMed - indexed for MEDLINE]
18.

[Experimental study of the function and mechanism combining dihydroartemisinin and gemcitabine in treating pancreatic cancer].

Wang SJ, Sun B, Pan SH, Chen H, Kong R, Li J, Xue DB, Bai XW, Jiang HC.

Zhonghua Wai Ke Za Zhi. 2010 Apr 1;48(7):530-4. Chinese.

PMID:
20646665
[PubMed - indexed for MEDLINE]
19.

Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets.

Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB.

Int J Cancer. 2012 Aug 1;131(3):E292-303. doi: 10.1002/ijc.26442. Epub 2011 Nov 9.

PMID:
21935918
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.

Harikumar KB, Kunnumakkara AB, Sethi G, Diagaradjane P, Anand P, Pandey MK, Gelovani J, Krishnan S, Guha S, Aggarwal BB.

Int J Cancer. 2010 Jul 15;127(2):257-68. doi: 10.1002/ijc.25041.

PMID:
19908231
[PubMed - indexed for MEDLINE]
Free PMC Article
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