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Results: 1 to 20 of 109

1.

Hematological changes as prognostic indicators of survival: similarities between Gottingen minipigs, humans, and other large animal models.

Moroni M, Lombardini E, Salber R, Kazemzedeh M, Nagy V, Olsen C, Whitnall MH.

PLoS One. 2011;6(9):e25210. doi: 10.1371/journal.pone.0025210. Epub 2011 Sep 28.

PMID:
21969873
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Hematopoietic radiation syndrome in the Gottingen minipig.

Moroni M, Coolbaugh TV, Lombardini E, Mitchell JM, Moccia KD, Shelton LJ, Nagy V, Whitnall MH.

Radiat Res. 2011 Jul;176(1):89-101. Epub 2011 Apr 26.

PMID:
21520996
[PubMed - indexed for MEDLINE]
3.

The Gottingen minipig is a model of the hematopoietic acute radiation syndrome: G-colony stimulating factor stimulates hematopoiesis and enhances survival from lethal total-body γ-irradiation.

Moroni M, Ngudiankama BF, Christensen C, Olsen CH, Owens R, Lombardini ED, Holt RK, Whitnall MH.

Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):986-92. doi: 10.1016/j.ijrobp.2013.04.041.

PMID:
23845847
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Acute hematological effects of solar particle event proton radiation in the porcine model.

Sanzari JK, Wan XS, Wroe AJ, Rightnar S, Cengel KA, Diffenderfer ES, Krigsfeld GS, Gridley DS, Kennedy AR.

Radiat Res. 2013 Jul;180(1):7-16. doi: 10.1667/RR3027.1. Epub 2013 May 14.

PMID:
23672458
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Accelerated hematopoietic syndrome after radiation doses bridging hematopoietic (H-ARS) and gastrointestinal (GI-ARS) acute radiation syndrome: early hematological changes and systemic inflammatory response syndrome in minipig.

Moroni M, Elliott TB, Deutz NE, Olsen CH, Owens R, Christensen C, Lombardini ED, Whitnall MH.

Int J Radiat Biol. 2014 May;90(5):363-72. doi: 10.3109/09553002.2014.892226.

PMID:
24524283
[PubMed - indexed for MEDLINE]
6.

Evaluation of the gamma-H2AX assay for radiation biodosimetry in a swine model.

Moroni M, Maeda D, Whitnall MH, Bonner WM, Redon CE.

Int J Mol Sci. 2013 Jul 8;14(7):14119-35. doi: 10.3390/ijms140714119.

PMID:
23880859
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Significance of bioindicators to predict survival in irradiated minipigs.

Moroni M, Port M, Koch A, Gulani J, Meineke V, Abend M.

Health Phys. 2014 Jun;106(6):727-33. doi: 10.1097/HP.0000000000000109.

PMID:
24776906
[PubMed - indexed for MEDLINE]
8.

Diagnosis and treatment of polonium poisoning.

Jefferson RD, Goans RE, Blain PG, Thomas SH.

Clin Toxicol (Phila). 2009 May;47(5):379-92. doi: 10.1080/15563650902956431. Review. Erratum in: Clin Toxicol (Phila). 2009 Jul;47(6):608.

PMID:
19492929
[PubMed - indexed for MEDLINE]
9.

Effect of total body X-ray irradiation on lymph node in Tibet minipig.

Wu SJ, Wang YJ, Guo KY, Chen C, Zhao TF, Sun MB, Gu WW, Gao YY, Han HJ, Zou F.

J Radiat Res. 2012;53(1):18-23. Epub 2011 Dec 1.

PMID:
22129563
[PubMed - indexed for MEDLINE]
Free Article
10.

Beta-cell function and mass in type 2 diabetes.

Larsen MO.

Dan Med Bull. 2009 Aug;56(3):153-64.

PMID:
19728971
[PubMed - indexed for MEDLINE]
11.

The minipig in toxicology.

Svendsen O.

Exp Toxicol Pathol. 2006 Jul;57(5-6):335-9. Epub 2006 May 24.

PMID:
16725317
[PubMed - indexed for MEDLINE]
12.

The acute gastrointestinal subsyndrome of the acute radiation syndrome: a rhesus macaque model.

MacVittie TJ, Farese AM, Bennett A, Gelfond D, Shea-Donohue T, Tudor G, Booth C, McFarland E, Jackson W 3rd.

Health Phys. 2012 Oct;103(4):411-26. doi: 10.1097/HP.0b013e31826525f0.

PMID:
22929470
[PubMed - indexed for MEDLINE]
13.

The RETHINK project on minipigs in the toxicity testing of new medicines and chemicals: conclusions and recommendations.

Forster R, Bode G, Ellegaard L, van der Laan JW.

J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):236-42. doi: 10.1016/j.vascn.2010.05.008. Epub 2010 May 31. Review.

PMID:
20685309
[PubMed - indexed for MEDLINE]
14.

Development of a new minipig model to study radiation-induced gastrointestinal syndrome and its application in clinical research.

Shim S, Jang WS, Lee SJ, Jin S, Kim J, Lee SS, Bang HY, Jeon BS, Park S.

Radiat Res. 2014 Apr;181(4):387-95. doi: 10.1667/RR13207.1.

PMID:
24786169
[PubMed - indexed for MEDLINE]
15.

The Göttingen minipig® as an alternative non-rodent species for immunogenicity testing: a demonstrator study using the IL-1 receptor antagonist anakinra.

van Mierlo GJ, Cnubben NH, Kuper CF, Wolthoorn J, van Meeteren-Kreikamp AP, Nagtegaal MM, Doornbos R, Ganderup NC, Penninks AH.

J Immunotoxicol. 2013 Jan-Mar;10(1):96-105. doi: 10.3109/1547691X.2012.735274. Epub 2012 Nov 7.

PMID:
23134195
[PubMed - indexed for MEDLINE]
16.

The utility of the minipig as an animal model in regulatory toxicology.

Bode G, Clausing P, Gervais F, Loegsted J, Luft J, Nogues V, Sims J; Steering Group of the RETHINK Project.

J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):196-220. doi: 10.1016/j.vascn.2010.05.009. Epub 2010 May 31. Review.

PMID:
20685310
[PubMed - indexed for MEDLINE]
17.

Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products.

van der Laan JW, Brightwell J, McAnulty P, Ratky J, Stark C; Steering Group of the RETHINK Project.

J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):184-95. doi: 10.1016/j.vascn.2010.05.005. Epub 2010 Jun 16. Review.

PMID:
20601024
[PubMed - indexed for MEDLINE]
19.

Hematologic effects of recombinant human interleukin-6 in dogs exposed to a total-body radiation dose of 2.4 Gy.

Selig C, Kreja L, Müller H, Seifried E, Nothdurft W.

Exp Hematol. 1994 Jul;22(7):551-8.

PMID:
8013570
[PubMed - indexed for MEDLINE]
20.

A physiologically based pharmacokinetic model of the minipig: data compilation and model implementation.

Suenderhauf C, Parrott N.

Pharm Res. 2013 Jan;30(1):1-15. doi: 10.1007/s11095-012-0911-5. Epub 2012 Nov 21. Review.

PMID:
23179779
[PubMed - indexed for MEDLINE]

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