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Results: 1 to 20 of 93

1.

Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype.

Mahimkar R, Alfonso-Jaume MA, Cape LM, Dahiya R, Lovett DH.

Carcinogenesis. 2011 Dec;32(12):1806-14. doi: 10.1093/carcin/bgr216. Epub 2011 Sep 28.

PMID:
21965271
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Constitutively active mitogen-activated protein kinase kinase MEK1 disrupts morphogenesis and induces an invasive phenotype in Madin-Darby canine kidney epithelial cells.

Montesano R, Soriano JV, Hosseini G, Pepper MS, Schramek H.

Cell Growth Differ. 1999 May;10(5):317-32.

PMID:
10359013
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells.

Schramek H, Feifel E, Marschitz I, Golochtchapova N, Gstraunthaler G, Montesano R.

Am J Physiol Cell Physiol. 2003 Sep;285(3):C652-61. Erratum in: Am J Physiol Cell Physiol. 2003 Dec;285(6):C1561.

PMID:
12900389
[PubMed - indexed for MEDLINE]
Free Article
5.
6.

Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities.

Lee KW, Kang NJ, Oak MH, Hwang MK, Kim JH, Schini-Kerth VB, Lee HJ.

Cardiovasc Res. 2008 Jul 1;79(1):34-41. doi: 10.1093/cvr/cvn056. Epub 2008 Mar 1.

PMID:
18310679
[PubMed - indexed for MEDLINE]
Free Article
7.

Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion.

Shields MA, Dangi-Garimella S, Krantz SB, Bentrem DJ, Munshi HG.

J Biol Chem. 2011 Mar 25;286(12):10495-504. doi: 10.1074/jbc.M110.195628. Epub 2011 Feb 2.

PMID:
21288898
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Membrane type 1 matrix metalloproteinase regulates collagen-dependent mitogen-activated protein/extracellular signal-related kinase activation and cell migration.

Takino T, Miyamori H, Watanabe Y, Yoshioka K, Seiki M, Sato H.

Cancer Res. 2004 Feb 1;64(3):1044-9.

PMID:
14871836
[PubMed - indexed for MEDLINE]
Free Article
9.

Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.

Sounni NE, Rozanov DV, Remacle AG, Golubkov VS, Noel A, Strongin AY.

Int J Cancer. 2010 Mar 1;126(5):1067-78. doi: 10.1002/ijc.24690. Erratum in: Int J Cancer. 2010 Apr 15;126(8):2002.

PMID:
19551841
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Membrane Type 1 Matrix Metalloproteinase induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells.

Yang CC, Zhu LF, Xu XH, Ning TY, Ye JH, Liu LK.

BMC Cancer. 2013 Apr 1;13:171. doi: 10.1186/1471-2407-13-171.

PMID:
23548172
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.

Pulyaeva H, Bueno J, Polette M, Birembaut P, Sato H, Seiki M, Thompson EW.

Clin Exp Metastasis. 1997 Mar;15(2):111-20. Erratum in: Clin Exp Metastasis 1997 May;15(3):338.

PMID:
9062387
[PubMed - indexed for MEDLINE]
14.

Transformation of epithelial Madin-Darby canine kidney cells with p60(v-src) induces expression of membrane-type 1 matrix metalloproteinase and invasiveness.

Kadono Y, Okada Y, Namiki M, Seiki M, Sato H.

Cancer Res. 1998 May 15;58(10):2240-4.

PMID:
9605772
[PubMed - indexed for MEDLINE]
Free Article
15.

3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases.

Xie Z, Yuan H, Yin Y, Zeng X, Bai R, Glazer RI.

BMC Cancer. 2006 Mar 21;6:77.

PMID:
16551362
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.

Jung YS, Liu XW, Chirco R, Warner RB, Fridman R, Kim HR.

PLoS One. 2012;7(6):e38773. doi: 10.1371/journal.pone.0038773. Epub 2012 Jun 11.

PMID:
22701711
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Constitutively active MEK1 is sufficient to induce epithelial-to-mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis.

Lemieux E, Bergeron S, Durand V, Asselin C, Saucier C, Rivard N.

Int J Cancer. 2009 Oct 1;125(7):1575-86. doi: 10.1002/ijc.24485.

PMID:
19462441
[PubMed - indexed for MEDLINE]
18.

Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.

Gilles C, Polette M, Seiki M, Birembaut P, Thompson EW.

Lab Invest. 1997 May;76(5):651-60.

PMID:
9166284
[PubMed - indexed for MEDLINE]
19.

Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.

SouliƩ P, Carrozzino F, Pepper MS, Strongin AY, Poupon MF, Montesano R.

Oncogene. 2005 Mar 3;24(10):1689-97.

PMID:
15608664
[PubMed - indexed for MEDLINE]
20.

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