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Results: 1 to 20 of 68

1.

Modeling psychiatric disorders through reprogramming.

Brennand KJ, Gage FH.

Dis Model Mech. 2012 Jan;5(1):26-32. doi: 10.1242/dmm.008268. Epub 2011 Oct 4. Review.

PMID:
21954066
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Modeling psychiatric disorders at the cellular and network levels.

Brennand KJ, Simone A, Tran N, Gage FH.

Mol Psychiatry. 2012 Dec;17(12):1239-53. doi: 10.1038/mp.2012.20. Epub 2012 Apr 3. Review.

PMID:
22472874
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome.

Sheridan SD, Theriault KM, Reis SA, Zhou F, Madison JM, Daheron L, Loring JF, Haggarty SJ.

PLoS One. 2011;6(10):e26203. doi: 10.1371/journal.pone.0026203. Epub 2011 Oct 12.

PMID:
22022567
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Modelling schizophrenia using human induced pluripotent stem cells.

Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, Sangar S, Li Y, Mu Y, Chen G, Yu D, McCarthy S, Sebat J, Gage FH.

Nature. 2011 May 12;473(7346):221-5. doi: 10.1038/nature09915. Epub 2011 Apr 13. Erratum in: Nature. 2011 Nov 24;479(7374):556.

PMID:
21490598
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Synaptic dysregulation in a human iPS cell model of mental disorders.

Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, Yoritomo N, Kaibuchi K, Zou J, Christian KM, Cheng L, Ross CA, Margolis RL, Chen G, Kosik KS, Song H, Ming GL.

Nature. 2014 Nov 20;515(7527):414-8. doi: 10.1038/nature13716. Epub 2014 Aug 17.

PMID:
25132547
[PubMed - indexed for MEDLINE]
6.

Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions.

Rodríguez-Pizà I, Richaud-Patin Y, Vassena R, González F, Barrero MJ, Veiga A, Raya A, Izpisúa Belmonte JC.

Stem Cells. 2010 Jan;28(1):36-44. doi: 10.1002/stem.248.

PMID:
19890879
[PubMed - indexed for MEDLINE]
Free Article
7.

Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons.

Tran NN, Ladran IG, Brennand KJ.

Schizophr Bull. 2013 Jan;39(1):4-10. doi: 10.1093/schbul/sbs127. Epub 2012 Nov 19.

PMID:
23172000
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia.

Brennand KJ, Gage FH.

Stem Cells. 2011 Dec;29(12):1915-22. doi: 10.1002/stem.762. Review.

PMID:
22009633
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.

Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS.

Nature. 2012 Jan 25;482(7384):216-20. doi: 10.1038/nature10821.

PMID:
22278060
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions.

Ambasudhan R, Talantova M, Coleman R, Yuan X, Zhu S, Lipton SA, Ding S.

Cell Stem Cell. 2011 Aug 5;9(2):113-8. doi: 10.1016/j.stem.2011.07.002. Epub 2011 Jul 28.

PMID:
21802386
[PubMed - indexed for MEDLINE]
Free Article
11.

SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs.

Lee P, Martin NT, Nakamura K, Azghadi S, Amiri M, Ben-David U, Perlman S, Gatti RA, Hu H, Lowry WE.

Nat Commun. 2013;4:1824. doi: 10.1038/ncomms2824.

PMID:
23652012
[PubMed - indexed for MEDLINE]
12.

Implications and limitations of cellular reprogramming for psychiatric drug development.

Tobe BT, Brandel MG, Nye JS, Snyder EY.

Exp Mol Med. 2013 Nov 15;45:e59. doi: 10.1038/emm.2013.124. Review.

PMID:
24232258
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Disease-specific, neurosphere-derived cells as models for brain disorders.

Matigian N, Abrahamsen G, Sutharsan R, Cook AL, Vitale AM, Nouwens A, Bellette B, An J, Anderson M, Beckhouse AG, Bennebroek M, Cecil R, Chalk AM, Cochrane J, Fan Y, Féron F, McCurdy R, McGrath JJ, Murrell W, Perry C, Raju J, Ravishankar S, Silburn PA, Sutherland GT, Mahler S, Mellick GD, Wood SA, Sue CM, Wells CA, Mackay-Sim A.

Dis Model Mech. 2010 Nov-Dec;3(11-12):785-98. doi: 10.1242/dmm.005447. Epub 2010 Aug 10.

PMID:
20699480
[PubMed - indexed for MEDLINE]
Free Article
14.

Modeling familial Alzheimer's disease with induced pluripotent stem cells.

Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N.

Hum Mol Genet. 2011 Dec 1;20(23):4530-9. doi: 10.1093/hmg/ddr394. Epub 2011 Sep 7.

PMID:
21900357
[PubMed - indexed for MEDLINE]
Free Article
15.

Human disease modeling with induced pluripotent stem cells.

Trounson A, Shepard KA, DeWitt ND.

Curr Opin Genet Dev. 2012 Oct;22(5):509-16. doi: 10.1016/j.gde.2012.07.004. Epub 2012 Aug 3. Review.

PMID:
22868174
[PubMed - indexed for MEDLINE]
16.

Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders.

Paulsen Bda S, da Silveira MS, Galina A, Rehen SK.

Arch Biochem Biophys. 2013 Jun;534(1-2):3-10. doi: 10.1016/j.abb.2012.10.009. Epub 2012 Oct 27. Review.

PMID:
23111185
[PubMed - indexed for MEDLINE]
17.

Potential application of induced pluripotent stem cells in cell replacement therapy for Parkinson's disease.

Chen LW, Kuang F, Wei LC, Ding YX, Yung KK, Chan YS.

CNS Neurol Disord Drug Targets. 2011 Jun;10(4):449-58. Review.

PMID:
21495962
[PubMed - indexed for MEDLINE]
18.

MicroRNA-mediated somatic cell reprogramming.

Kuo CH, Ying SY.

J Cell Biochem. 2013 Feb;114(2):275-81. doi: 10.1002/jcb.24385.

PMID:
22961769
[PubMed - indexed for MEDLINE]
19.

Avian-induced pluripotent stem cells derived using human reprogramming factors.

Lu Y, West FD, Jordan BJ, Mumaw JL, Jordan ET, Gallegos-Cardenas A, Beckstead RB, Stice SL.

Stem Cells Dev. 2012 Feb 10;21(3):394-403. doi: 10.1089/scd.2011.0499. Epub 2011 Nov 16.

PMID:
21970437
[PubMed - indexed for MEDLINE]
20.

A blueprint for engineering cell fate: current technologies to reprogram cell identity.

Morris SA, Daley GQ.

Cell Res. 2013 Jan;23(1):33-48. doi: 10.1038/cr.2013.1. Epub 2013 Jan 1. Review.

PMID:
23277278
[PubMed - indexed for MEDLINE]
Free PMC Article
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