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Related Citations for PubMed (Select 21925225)


Interleukin (IL)-2 and IL-15 have different effects on human natural killer lymphocytes.

Pillet AH, Thèze J, Rose T.

Hum Immunol. 2011 Nov;72(11):1013-7. doi: 10.1016/j.humimm.2011.07.311. Epub 2011 Sep 1.


A programmed switch from IL-15- to IL-2-dependent activation in human NK cells.

Pillet AH, Bugault F, Thèze J, Chakrabarti LA, Rose T.

J Immunol. 2009 May 15;182(10):6267-77. doi: 10.4049/jimmunol.0801933.


Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells.

Grund EM, Spyropoulos DD, Watson DK, Muise-Helmericks RC.

J Biol Chem. 2005 Feb 11;280(6):4772-8. Epub 2004 Nov 23.


A potential role for interleukin-15 in the regulation of human natural killer cell survival.

Carson WE, Fehniger TA, Haldar S, Eckhert K, Lindemann MJ, Lai CF, Croce CM, Baumann H, Caligiuri MA.

J Clin Invest. 1997 Mar 1;99(5):937-43.


Implications for gene therapy-limiting expression of IL-2R gamma c delineate differences in signaling thresholds required for lymphocyte development and maintenance.

Orr SJ, Roessler S, Quigley L, Chan T, Ford JW, O'Connor GM, McVicar DW.

J Immunol. 2010 Aug 1;185(3):1393-403. doi: 10.4049/jimmunol.0903528. Epub 2010 Jun 30.


A potential role for hydrocortisone in the positive regulation of IL-15-activated NK-cell proliferation and survival.

Perez SA, Mahaira LG, Demirtzoglou FJ, Sotiropoulou PA, Ioannidis P, Iliopoulou EG, Gritzapis AD, Sotiriadou NN, Baxevanis CN, Papamichail M.

Blood. 2005 Jul 1;106(1):158-66. Epub 2005 Mar 8.


IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.

Hansen ML, Woetmann A, Krejsgaard T, Kopp KL, Søkilde R, Litman T, Straten PT, Geisler C, Wasik MA, Odum N, Eriksen KW.

Mol Immunol. 2011 Sep;48(15-16):2087-93. doi: 10.1016/j.molimm.2011.07.008. Epub 2011 Aug 2.


Growth and apoptosis of human natural killer cell neoplasms: role of interleukin-2/15 signaling.

Yamasaki S, Maeda M, Ohshima K, Kikuchi M, Otsuka T, Harada M.

Leuk Res. 2004 Oct;28(10):1023-31.


A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.

Rafei M, Wu JH, Annabi B, Lejeune L, François M, Galipeau J.

Blood. 2007 Mar 1;109(5):2234-42. Epub 2006 Nov 2.


Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells.

Leong JW, Chase JM, Romee R, Schneider SE, Sullivan RP, Cooper MA, Fehniger TA.

Biol Blood Marrow Transplant. 2014 Apr;20(4):463-73. doi: 10.1016/j.bbmt.2014.01.006. Epub 2014 Jan 13.


Enforced expression of Bcl-2 restores the number of NK cells, but does not rescue the impaired development of NKT cells or intraepithelial lymphocytes, in IL-2/IL-15 receptor beta-chain-deficient mice.

Minagawa M, Watanabe H, Miyaji C, Tomiyama K, Shimura H, Ito A, Ito M, Domen J, Weissman IL, Kawai K.

J Immunol. 2002 Oct 15;169(8):4153-60.


NK cells provide helper signal for CD8+ T cells by inducing the expression of membrane-bound IL-15 on DCs.

Morandi B, Mortara L, Carrega P, Cantoni C, Costa G, Accolla RS, Mingari MC, Ferrini S, Moretta L, Ferlazzo G.

Int Immunol. 2009 May;21(5):599-606. doi: 10.1093/intimm/dxp029. Epub 2009 Mar 26.


Proliferation and differentiation of CD8+ T cells in the absence of IL-2/15 receptor beta-chain expression or STAT5 activation.

Teague RM, Tempero RM, Thomas S, Murali-Krishna K, Nelson BH.

J Immunol. 2004 Sep 1;173(5):3131-9.


Cytokine requirements for the growth and development of mouse NK cells in vitro.

Toomey JA, Gays F, Foster D, Brooks CG.

J Leukoc Biol. 2003 Aug;74(2):233-42.


Membrane-bound IL-15 stimulation on peripheral blood natural kiler progenitors leads to the generation of an adherent subset co-expressing dendritic cells and natural kiler functional markers.

Negrini S, Giuliani M, Durali D, Chouaib S, Azzarone B.

Haematologica. 2011 May;96(5):762-6. doi: 10.3324/haematol.2010.033738. Epub 2011 Jan 17.


Differential regulation of interleukin-12- and interleukin-15-induced natural killer cell activation by interleukin-4.

Salvucci O, Mami-Chouaib F, Moreau JL, Thèze J, Chehimi J, Chouaib S.

Eur J Immunol. 1996 Nov;26(11):2736-41.

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