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Results: 1 to 20 of 98

1.

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5.

Bell DW, Sikdar N, Lee KY, Price JC, Chatterjee R, Park HD, Fox J, Ishiai M, Rudd ML, Pollock LM, Fogoros SK, Mohamed H, Hanigan CL; NISC Comparative Sequencing Program, Zhang S, Cruz P, Renaud G, Hansen NF, Cherukuri PF, Borate B, McManus KJ, Stoepel J, Sipahimalani P, Godwin AK, Sgroi DC, Merino MJ, Elliot G, Elkahloun A, Vinson C, Takata M, Mullikin JC, Wolfsberg TG, Hieter P, Lim DS, Myung K.

PLoS Genet. 2011 Aug;7(8):e1002245. doi: 10.1371/journal.pgen.1002245. Epub 2011 Aug 25.

PMID:
21901109
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?

Kubota T, Myung K, Donaldson AD.

Cell Cycle. 2013 Aug 15;12(16):2570-9. doi: 10.4161/cc.25626. Epub 2013 Jul 10. Review.

PMID:
23907118
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin.

Lee KY, Fu H, Aladjem MI, Myung K.

J Cell Biol. 2013 Jan 7;200(1):31-44. doi: 10.1083/jcb.201206084. Epub 2012 Dec 31.

PMID:
23277426
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.

Lee KY, Yang K, Cohn MA, Sikdar N, D'Andrea AD, Myung K.

J Biol Chem. 2010 Apr 2;285(14):10362-9. doi: 10.1074/jbc.M109.092544. Epub 2010 Feb 9.

PMID:
20147293
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis.

Venkatesan RN, Treuting PM, Fuller ED, Goldsby RE, Norwood TH, Gooley TA, Ladiges WC, Preston BD, Loeb LA.

Mol Cell Biol. 2007 Nov;27(21):7669-82. Epub 2007 Sep 4.

PMID:
17785453
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Dynamic regulation of PCNA ubiquitylation/deubiquitylation.

Fox JT, Lee KY, Myung K.

FEBS Lett. 2011 Sep 16;585(18):2780-5. doi: 10.1016/j.febslet.2011.05.053. Epub 2011 Jun 1. Review.

PMID:
21640107
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

ATAD5 deficiency decreases B cell division and Igh recombination.

Zanotti KJ, Maul RW, Castiblanco DP, Yang W, Choi YJ, Fox JT, Myung K, Saribasak H, Gearhart PJ.

J Immunol. 2015 Jan 1;194(1):35-42. doi: 10.4049/jimmunol.1401158. Epub 2014 Nov 17.

PMID:
25404367
[PubMed - in process]
8.

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks.

Motegi A, Liaw HJ, Lee KY, Roest HP, Maas A, Wu X, Moinova H, Markowitz SD, Ding H, Hoeijmakers JH, Myung K.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12411-6. doi: 10.1073/pnas.0805685105. Epub 2008 Aug 21.

PMID:
18719106
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer.

Zheng L, Dai H, Hegde ML, Zhou M, Guo Z, Wu X, Wu J, Su L, Zhong X, Mitra S, Huang Q, Kernstine KH, Pfeifer GP, Shen B.

Cell Res. 2011 Jul;21(7):1052-67. doi: 10.1038/cr.2011.35. Epub 2011 Mar 8.

PMID:
21383776
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome.

Mann MB, Hodges CA, Barnes E, Vogel H, Hassold TJ, Luo G.

Hum Mol Genet. 2005 Mar 15;14(6):813-25. Epub 2005 Feb 9.

PMID:
15703196
[PubMed - indexed for MEDLINE]
Free Article
11.

Functional and physical interaction of yeast Mgs1 with PCNA: impact on RAD6-dependent DNA damage tolerance.

Hishida T, Ohya T, Kubota Y, Kamada Y, Shinagawa H.

Mol Cell Biol. 2006 Jul;26(14):5509-17.

PMID:
16809783
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

New insights into replication clamp unloading.

Ulrich HD.

J Mol Biol. 2013 Nov 29;425(23):4727-32. doi: 10.1016/j.jmb.2013.05.003. Epub 2013 May 17. Review.

PMID:
23688817
[PubMed - indexed for MEDLINE]
13.

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

Song H, Hollstein M, Xu Y.

Nat Cell Biol. 2007 May;9(5):573-80. Epub 2007 Apr 8.

PMID:
17417627
[PubMed - indexed for MEDLINE]
14.

Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis.

Akbay EA, Peña CG, Ruder D, Michel JA, Nakada Y, Pathak S, Multani AS, Chang S, Castrillon DH.

Oncogene. 2013 Apr 25;32(17):2211-9. doi: 10.1038/onc.2012.232. Epub 2012 Jun 11.

PMID:
22689059
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA.

Andersen PL, Xu F, Xiao W.

Cell Res. 2008 Jan;18(1):162-73. Review.

PMID:
18157158
[PubMed - indexed for MEDLINE]
Free Article
16.

The importance of being modified: PCNA modification and DNA damage response.

Gazy I, Kupiec M.

Cell Cycle. 2012 Jul 15;11(14):2620-3. doi: 10.4161/cc.20626. Epub 2012 Jul 15.

PMID:
22732495
[PubMed - indexed for MEDLINE]
17.

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.

Bartkova J, Horejsí Z, Koed K, Krämer A, Tort F, Zieger K, Guldberg P, Sehested M, Nesland JM, Lukas C, Ørntoft T, Lukas J, Bartek J.

Nature. 2005 Apr 14;434(7035):864-70.

PMID:
15829956
[PubMed - indexed for MEDLINE]
18.

Aneuploidy drives genomic instability in yeast.

Sheltzer JM, Blank HM, Pfau SJ, Tange Y, George BM, Humpton TJ, Brito IL, Hiraoka Y, Niwa O, Amon A.

Science. 2011 Aug 19;333(6045):1026-30. doi: 10.1126/science.1206412.

PMID:
21852501
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.

Halaby MJ, Hakem A, Li L, El Ghamrasni S, Venkatesan S, Hande PM, Sanchez O, Hakem R.

PLoS Genet. 2013;9(1):e1003259. doi: 10.1371/journal.pgen.1003259. Epub 2013 Jan 31.

PMID:
23382699
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

p73 suppresses polyploidy and aneuploidy in the absence of functional p53.

Talos F, Nemajerova A, Flores ER, Petrenko O, Moll UM.

Mol Cell. 2007 Aug 17;27(4):647-59.

PMID:
17707235
[PubMed - indexed for MEDLINE]
Free Article
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