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Results: 1 to 20 of 82

1.

Evidence that gene activation and silencing during stem cell differentiation requires a transcriptionally paused intermediate state.

Golob JL, Kumar RM, Guenther MG, Pabon LM, Pratt GA, Loring JF, Laurent LC, Young RA, Murry CE.

PLoS One. 2011;6(8):e22416. doi: 10.1371/journal.pone.0022416. Epub 2011 Aug 19.

PMID:
21886766
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency.

Hawkins RD, Hon GC, Yang C, Antosiewicz-Bourget JE, Lee LK, Ngo QM, Klugman S, Ching KA, Edsall LE, Ye Z, Kuan S, Yu P, Liu H, Zhang X, Green RD, Lobanenkov VV, Stewart R, Thomson JA, Ren B.

Cell Res. 2011 Oct;21(10):1393-409. doi: 10.1038/cr.2011.146. Epub 2011 Aug 30.

PMID:
21876557
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Global transcription in pluripotent embryonic stem cells.

Efroni S, Duttagupta R, Cheng J, Dehghani H, Hoeppner DJ, Dash C, Bazett-Jones DP, Le Grice S, McKay RD, Buetow KH, Gingeras TR, Misteli T, Meshorer E.

Cell Stem Cell. 2008 May 8;2(5):437-47. doi: 10.1016/j.stem.2008.03.021.

PMID:
18462694
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Developmental pluripotency-associated 4 (DPPA4) localized in active chromatin inhibits mouse embryonic stem cell differentiation into a primitive ectoderm lineage.

Masaki H, Nishida T, Kitajima S, Asahina K, Teraoka H.

J Biol Chem. 2007 Nov 9;282(45):33034-42. Epub 2007 Sep 13.

PMID:
17855347
[PubMed - indexed for MEDLINE]
Free Article
5.

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells.

Sheik Mohamed J, Gaughwin PM, Lim B, Robson P, Lipovich L.

RNA. 2010 Feb;16(2):324-37. doi: 10.1261/rna.1441510. Epub 2009 Dec 21.

PMID:
20026622
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Generation of platform human embryonic stem cell lines that allow efficient targeting at a predetermined genomic location.

Liu Y, Thyagarajan B, Lakshmipathy U, Xue H, Lieu P, Fontes A, MacArthur CC, Scheyhing K, Rao MS, Chesnut JD.

Stem Cells Dev. 2009 Dec;18(10):1459-72. doi: 10.1089/scd.2009.0047.

PMID:
19355838
[PubMed - indexed for MEDLINE]
7.

Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells.

Min IM, Waterfall JJ, Core LJ, Munroe RJ, Schimenti J, Lis JT.

Genes Dev. 2011 Apr 1;25(7):742-54. doi: 10.1101/gad.2005511.

PMID:
21460038
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions.

Abrajano JJ, Qureshi IA, Gokhan S, Molero AE, Zheng D, Bergman A, Mehler MF.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16685-90. doi: 10.1073/pnas.0906917107. Epub 2010 Sep 7.

PMID:
20823235
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Dnmt3a1 upregulates transcription of distinct genes and targets chromosomal gene clusters for epigenetic silencing in mouse embryonic stem cells.

Kotini AG, Mpakali A, Agalioti T.

Mol Cell Biol. 2011 Apr;31(7):1577-92. doi: 10.1128/MCB.01093-10. Epub 2011 Jan 24.

PMID:
21262766
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Histone h1 depletion impairs embryonic stem cell differentiation.

Zhang Y, Cooke M, Panjwani S, Cao K, Krauth B, Ho PY, Medrzycki M, Berhe DT, Pan C, McDevitt TC, Fan Y.

PLoS Genet. 2012;8(5):e1002691. doi: 10.1371/journal.pgen.1002691. Epub 2012 May 10.

PMID:
22589736
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The "occlusis" model of cell fate restriction.

Lahn BT.

Bioessays. 2011 Jan;33(1):13-20. doi: 10.1002/bies.201000090. Epub 2010 Oct 15.

PMID:
20954221
[PubMed - indexed for MEDLINE]
12.

Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells.

Zhao XD, Han X, Chew JL, Liu J, Chiu KP, Choo A, Orlov YL, Sung WK, Shahab A, Kuznetsov VA, Bourque G, Oh S, Ruan Y, Ng HH, Wei CL.

Cell Stem Cell. 2007 Sep 13;1(3):286-98. doi: 10.1016/j.stem.2007.08.004.

PMID:
18371363
[PubMed - indexed for MEDLINE]
Free Article
13.

Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.

Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M.

Mol Cell. 2009 Feb 27;33(4):417-27. doi: 10.1016/j.molcel.2009.02.004.

PMID:
19250903
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells.

Kidder BL, Yang J, Palmer S.

PLoS One. 2008;3(12):e3932. doi: 10.1371/journal.pone.0003932. Epub 2008 Dec 11.

PMID:
19079543
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Epigenetic signatures and temporal expression of lineage-specific genes in hESCs during differentiation to hepatocytes in vitro.

Kim H, Jang MJ, Kang MJ, Han YM.

Hum Mol Genet. 2011 Feb 1;20(3):401-12. doi: 10.1093/hmg/ddq476. Epub 2010 Nov 8.

PMID:
21059703
[PubMed - indexed for MEDLINE]
Free Article
16.

Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC).

Lin C, Garrett AS, De Kumar B, Smith ER, Gogol M, Seidel C, Krumlauf R, Shilatifard A.

Genes Dev. 2011 Jul 15;25(14):1486-98. doi: 10.1101/gad.2059211.

PMID:
21764852
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Transcriptional silencing of a novel hTERT reporter locus during in vitro differentiation of mouse embryonic stem cells.

Wang S, Hu C, Zhu J.

Mol Biol Cell. 2007 Feb;18(2):669-77. Epub 2006 Dec 6.

PMID:
17151355
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Epigenetic landscaping during hESC differentiation to neural cells.

Golebiewska A, Atkinson SP, Lako M, Armstrong L.

Stem Cells. 2009 Jun;27(6):1298-308. doi: 10.1002/stem.59.

PMID:
19489095
[PubMed - indexed for MEDLINE]
Free Article
19.

Enhancer decommissioning by LSD1 during embryonic stem cell differentiation.

Whyte WA, Bilodeau S, Orlando DA, Hoke HA, Frampton GM, Foster CT, Cowley SM, Young RA.

Nature. 2012 Feb 1;482(7384):221-5. doi: 10.1038/nature10805.

PMID:
22297846
[PubMed - indexed for MEDLINE]
20.

Chromatin signature of embryonic pluripotency is established during genome activation.

Vastenhouw NL, Zhang Y, Woods IG, Imam F, Regev A, Liu XS, Rinn J, Schier AF.

Nature. 2010 Apr 8;464(7290):922-6. doi: 10.1038/nature08866. Epub 2010 Mar 24.

PMID:
20336069
[PubMed - indexed for MEDLINE]
Free PMC Article

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