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Items: 1 to 20 of 159

1.

Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation.

Hu X, Zhou H, Zhang D, Yang S, Qian L, Wu HM, Chen PS, Wilson B, Gao HM, Lu RB, Hong JS.

J Neuroimmune Pharmacol. 2012 Mar;7(1):187-201. doi: 10.1007/s11481-011-9309-0. Epub 2011 Aug 26.

2.

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

J Neuroinflammation. 2008 May 28;5:21. doi: 10.1186/1742-2094-5-21.

3.
4.

3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Zhang W, Kim HC, Hong JS.

FASEB J. 2005 Mar;19(3):395-7. Epub 2004 Dec 13.

5.

Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

Li Y, Hu X, Liu Y, Bao Y, An L.

Neuropharmacology. 2009 Mar;56(3):580-9. doi: 10.1016/j.neuropharm.2008.10.016. Epub 2008 Nov 21.

PMID:
19049811
6.

Aspirin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity in primary midbrain cultures.

Wang F, Zhai H, Huang L, Li H, Xu Y, Qiao X, Sun S, Wu Y.

J Mol Neurosci. 2012 Jan;46(1):153-61. doi: 10.1007/s12031-011-9541-3. Epub 2011 May 17.

PMID:
21584653
7.

Microglia-mediated neurotoxicity is inhibited by morphine through an opioid receptor-independent reduction of NADPH oxidase activity.

Qian L, Tan KS, Wei SJ, Wu HM, Xu Z, Wilson B, Lu RB, Hong JS, Flood PM.

J Immunol. 2007 Jul 15;179(2):1198-209.

8.

Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS.

J Pharmacol Exp Ther. 2003 Apr;305(1):212-8.

9.

Verapamil protects dopaminergic neuron damage through a novel anti-inflammatory mechanism by inhibition of microglial activation.

Liu Y, Lo YC, Qian L, Crews FT, Wilson B, Chen HL, Wu HM, Chen SH, Wei K, Lu RB, Ali S, Hong JS.

Neuropharmacology. 2011 Feb-Mar;60(2-3):373-80. doi: 10.1016/j.neuropharm.2010.10.002. Epub 2010 Oct 13.

10.

Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions.

Zhang F, Shi JS, Zhou H, Wilson B, Hong JS, Gao HM.

Mol Pharmacol. 2010 Sep;78(3):466-77. doi: 10.1124/mol.110.064535. Epub 2010 Jun 16. Erratum in: Mol Pharmacol. 2010 Nov;78(5):981.

11.

Catalpol protects dopaminergic neurons from LPS-induced neurotoxicity in mesencephalic neuron-glia cultures.

Tian YY, An LJ, Jiang L, Duan YL, Chen J, Jiang B.

Life Sci. 2006 Dec 23;80(3):193-9. Epub 2006 Sep 20.

PMID:
17049947
12.

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS.

J Biol Chem. 2004 Jan 9;279(2):1415-21. Epub 2003 Oct 24.

13.

Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress.

Yang S, Yang J, Yang Z, Chen P, Fraser A, Zhang W, Pang H, Gao X, Wilson B, Hong JS, Block ML.

J Pharmacol Exp Ther. 2006 Nov;319(2):595-603. Epub 2006 Aug 4.

14.

HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.

Gao HM, Zhou H, Zhang F, Wilson BC, Kam W, Hong JS.

J Neurosci. 2011 Jan 19;31(3):1081-92. doi: 10.1523/JNEUROSCI.3732-10.2011.

15.

A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis.

Jiang L, Chen SH, Chu CH, Wang SJ, Oyarzabal E, Wilson B, Sanders V, Xie K, Wang Q, Hong JS.

Glia. 2015 Jun;63(6):1057-72. doi: 10.1002/glia.22801. Epub 2015 Mar 4.

PMID:
25740080
16.

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase.

Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM.

J Pharmacol Exp Ther. 2006 Oct;319(1):44-52. Epub 2006 Jun 28.

17.
18.

The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

Tran TA, McCoy MK, Sporn MB, Tansey MG.

J Neuroinflammation. 2008 May 12;5:14. doi: 10.1186/1742-2094-5-14.

19.

Paeonol attenuates microglia-mediated inflammation and oxidative stress-induced neurotoxicity in rat primary microglia and cortical neurons.

Tseng YT, Hsu YY, Shih YT, Lo YC.

Shock. 2012 Mar;37(3):312-8. doi: 10.1097/SHK.0b013e31823fe939.

PMID:
22089194
20.

Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation.

Chung YC, Kim SR, Park JY, Chung ES, Park KW, Won SY, Bok E, Jin M, Park ES, Yoon SH, Ko HW, Kim YS, Jin BK.

Neuropharmacology. 2011 May;60(6):963-74. doi: 10.1016/j.neuropharm.2011.01.043. Epub 2011 Feb 1.

PMID:
21288472
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