Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 194

1.

Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Sage J, Butte AJ.

Sci Transl Med. 2011 Aug 17;3(96):96ra77. doi: 10.1126/scitranslmed.3001318. Erratum in: Sci Transl Med. 2011 Sep 28;3(102):102er7.

2.

Drug target prediction and repositioning using an integrated network-based approach.

Emig D, Ivliev A, Pustovalova O, Lancashire L, Bureeva S, Nikolsky Y, Bessarabova M.

PLoS One. 2013 Apr 4;8(4):e60618. doi: 10.1371/journal.pone.0060618. Print 2013.

3.

PREDICT: a method for inferring novel drug indications with application to personalized medicine.

Gottlieb A, Stein GY, Ruppin E, Sharan R.

Mol Syst Biol. 2011 Jun 7;7:496. doi: 10.1038/msb.2011.26.

4.

Exploiting drug-disease relationships for computational drug repositioning.

Dudley JT, Deshpande T, Butte AJ.

Brief Bioinform. 2011 Jul;12(4):303-11. doi: 10.1093/bib/bbr013. Epub 2011 Jun 20. Review.

5.

Computational drug repositioning: from data to therapeutics.

Hurle MR, Yang L, Xie Q, Rajpal DK, Sanseau P, Agarwal P.

Clin Pharmacol Ther. 2013 Apr;93(4):335-41. doi: 10.1038/clpt.2013.1. Epub 2013 Jan 15. Review.

PMID:
23443757
6.

Drug repositioning for orphan genetic diseases through Conserved Anticoexpressed Gene Clusters (CAGCs).

Molineris I, Ala U, Provero P, Di Cunto F.

BMC Bioinformatics. 2013 Oct 2;14:288. doi: 10.1186/1471-2105-14-288.

7.

Computational drug repositioning through heterogeneous network clustering.

Wu C, Gudivada RC, Aronow BJ, Jegga AG.

BMC Syst Biol. 2013;7 Suppl 5:S6. doi: 10.1186/1752-0509-7-S5-S6. Epub 2013 Dec 9.

8.

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.

Lee HS, Bae T, Lee JH, Kim DG, Oh YS, Jang Y, Kim JT, Lee JJ, Innocenti A, Supuran CT, Chen L, Rho K, Kim S.

BMC Syst Biol. 2012 Jul 2;6:80. doi: 10.1186/1752-0509-6-80.

9.

Computational drug repositioning for cancer therapeutics.

Jiao M, Liu G, Xue Y, Ding C.

Curr Top Med Chem. 2015;15(8):767-75.

PMID:
25732789
10.

CANDO and the infinite drug discovery frontier.

Minie M, Chopra G, Sethi G, Horst J, White G, Roy A, Hatti K, Samudrala R.

Drug Discov Today. 2014 Sep;19(9):1353-63. doi: 10.1016/j.drudis.2014.06.018. Epub 2014 Jun 26. Review.

11.

In silico drug repositioning: what we need to know.

Liu Z, Fang H, Reagan K, Xu X, Mendrick DL, Slikker W Jr, Tong W.

Drug Discov Today. 2013 Feb;18(3-4):110-5. doi: 10.1016/j.drudis.2012.08.005. Epub 2012 Aug 28.

PMID:
22935104
12.

Predicting new indications for approved drugs using a proteochemometric method.

Dakshanamurthy S, Issa NT, Assefnia S, Seshasayee A, Peters OJ, Madhavan S, Uren A, Brown ML, Byers SW.

J Med Chem. 2012 Aug 9;55(15):6832-48. doi: 10.1021/jm300576q. Epub 2012 Jul 25.

13.

Drug repositioning framework by incorporating functional information.

Wu Z, Wang Y, Chen L.

IET Syst Biol. 2013 Oct;7(5):188-94. doi: 10.1049/iet-syb.2012.0064.

PMID:
24067419
14.

A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases.

Berenstein AJ, Magariños MP, Chernomoretz A, Agüero F.

PLoS Negl Trop Dis. 2016 Jan 6;10(1):e0004300. doi: 10.1371/journal.pntd.0004300. eCollection 2016 Jan.

15.

Multi-aspect candidates for repositioning: data fusion methods using heterogeneous information sources.

Arany Á, Bolgár B, Balogh B, Antal P, Mátyus P.

Curr Med Chem. 2013;20(1):95-107.

PMID:
23210850
16.

A computational approach to finding novel targets for existing drugs.

Li YY, An J, Jones SJ.

PLoS Comput Biol. 2011 Sep;7(9):e1002139. doi: 10.1371/journal.pcbi.1002139. Epub 2011 Sep 1.

17.

Assessing drug target association using semantic linked data.

Chen B, Ding Y, Wild DJ.

PLoS Comput Biol. 2012;8(7):e1002574. doi: 10.1371/journal.pcbi.1002574. Epub 2012 Jul 5.

18.

Predicting targeted polypharmacology for drug repositioning and multi- target drug discovery.

Liu X, Zhu F, Ma XH, Shi Z, Yang SY, Wei YQ, Chen YZ.

Curr Med Chem. 2013;20(13):1646-61. Review.

PMID:
23410165
19.

PhenoPredict: A disease phenome-wide drug repositioning approach towards schizophrenia drug discovery.

Xu R, Wang Q.

J Biomed Inform. 2015 Aug;56:348-55. doi: 10.1016/j.jbi.2015.06.027. Epub 2015 Jul 4.

20.

Computational and experimental advances in drug repositioning for accelerated therapeutic stratification.

Shameer K, Readhead B, Dudley JT.

Curr Top Med Chem. 2015;15(1):5-20. Review.

PMID:
25579574
Items per page

Supplemental Content

Write to the Help Desk