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Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe.

Kiely CM, Marguerat S, Garcia JF, Madhani HD, Bähler J, Winston F.

Mol Cell Biol. 2011 Oct;31(20):4193-204. doi: 10.1128/MCB.05568-11. Epub 2011 Aug 15.


Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3.

Kato H, Okazaki K, Iida T, Nakayama J, Murakami Y, Urano T.

Sci Rep. 2013;3:2186. doi: 10.1038/srep02186.


Coordination of DNA replication and histone modification by the Rik1-Dos2 complex.

Li F, Martienssen R, Cande WZ.

Nature. 2011 Jul 3;475(7355):244-8. doi: 10.1038/nature10161.


Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast.

DeGennaro CM, Alver BH, Marguerat S, Stepanova E, Davis CP, Bähler J, Park PJ, Winston F.

Mol Cell Biol. 2013 Dec;33(24):4779-92. doi: 10.1128/MCB.01068-13. Epub 2013 Oct 7.


H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases.

Hansen KR, Hazan I, Shanker S, Watt S, Verhein-Hansen J, Bähler J, Martienssen RA, Partridge JF, Cohen A, Thon G.

PLoS Genet. 2011 Jan 6;7(1):e1001268. doi: 10.1371/journal.pgen.1001268.


Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres.

Chinen M, Morita M, Fukumura K, Tani T.

J Biol Chem. 2010 Feb 19;285(8):5630-8. doi: 10.1074/jbc.M109.074393. Epub 2009 Dec 14.


Argonaute slicing is required for heterochromatic silencing and spreading.

Irvine DV, Zaratiegui M, Tolia NH, Goto DB, Chitwood DH, Vaughn MW, Joshua-Tor L, Martienssen RA.

Science. 2006 Aug 25;313(5790):1134-7.


HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms.

Motamedi MR, Hong EJ, Li X, Gerber S, Denison C, Gygi S, Moazed D.

Mol Cell. 2008 Dec 26;32(6):778-90. doi: 10.1016/j.molcel.2008.10.026.


A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast.

Sansó M, Lee KM, Viladevall L, Jacques PÉ, Pagé V, Nagy S, Racine A, St Amour CV, Zhang C, Shokat KM, Schwer B, Robert F, Fisher RP, Tanny JC.

PLoS Genet. 2012;8(8):e1002822. doi: 10.1371/journal.pgen.1002822. Epub 2012 Aug 2.


RNAi-mediated heterochromatin assembly in fission yeast.

Zofall M, Grewal SI.

Cold Spring Harb Symp Quant Biol. 2006;71:487-96. Review.


Studies on the mechanism of RNAi-dependent heterochromatin assembly.

Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP.

Cold Spring Harb Symp Quant Biol. 2006;71:461-71. Review.


Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci.

Yamane K, Mizuguchi T, Cui B, Zofall M, Noma K, Grewal SI.

Mol Cell. 2011 Jan 7;41(1):56-66. doi: 10.1016/j.molcel.2010.12.009.


Two ubiquitin-conjugating enzymes, Rhp6 and UbcX, regulate heterochromatin silencing in Schizosaccharomyces pombe.

Choi ES, Kim HS, Jang YK, Hong SH, Park SD.

Mol Cell Biol. 2002 Dec;22(23):8366-74.


The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe.

Thon G, Hansen KR, Altes SP, Sidhu D, Singh G, Verhein-Hansen J, Bonaduce MJ, Klar AJ.

Genetics. 2005 Dec;171(4):1583-95. Epub 2005 Sep 12.


Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.

Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA.

Science. 2002 Sep 13;297(5588):1833-7. Epub 2002 Aug 22.


RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production.

Sugiyama T, Cam H, Verdel A, Moazed D, Grewal SI.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):152-7. Epub 2004 Dec 22.

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