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Results: 1 to 20 of 103

1.

The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.

Maures TJ, Greer EL, Hauswirth AG, Brunet A.

Aging Cell. 2011 Dec;10(6):980-90. doi: 10.1111/j.1474-9726.2011.00738.x. Epub 2011 Sep 16.

PMID:
21834846
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.

Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A.

Nature. 2010 Jul 15;466(7304):383-7. doi: 10.1038/nature09195. Epub 2010 Jun 16.

PMID:
20555324
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway.

Jin C, Li J, Green CD, Yu X, Tang X, Han D, Xian B, Wang D, Huang X, Cao X, Yan Z, Hou L, Liu J, Shukeir N, Khaitovich P, Chen CD, Zhang H, Jenuwein T, Han JD.

Cell Metab. 2011 Aug 3;14(2):161-72. doi: 10.1016/j.cmet.2011.07.001.

PMID:
21803287
[PubMed - indexed for MEDLINE]
Free Article
4.

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans.

Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, Brunet A.

Nature. 2011 Oct 19;479(7373):365-71. doi: 10.1038/nature10572.

PMID:
22012258
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.

Mansour AA, Gafni O, Weinberger L, Zviran A, Ayyash M, Rais Y, Krupalnik V, Zerbib M, Amann-Zalcenstein D, Maza I, Geula S, Viukov S, Holtzman L, Pribluda A, Canaani E, Horn-Saban S, Amit I, Novershtern N, Hanna JH.

Nature. 2012 Aug 16;488(7411):409-13. doi: 10.1038/nature11272.

PMID:
22801502
[PubMed - indexed for MEDLINE]
6.

The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity.

Vandamme J, Lettier G, Sidoli S, Di Schiavi E, Nørregaard Jensen O, Salcini AE.

PLoS Genet. 2012;8(5):e1002647. doi: 10.1371/journal.pgen.1002647. Epub 2012 May 3.

PMID:
22570628
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

HTZ-1/H2A.z and MYS-1/MYST HAT act redundantly to maintain cell fates in somatic gonadal cells through repression of ceh-22 in C. elegans.

Shibata Y, Sawa H, Nishiwaki K.

Development. 2014 Jan;141(1):209-18. doi: 10.1242/dev.090746.

PMID:
24346701
[PubMed - indexed for MEDLINE]
Free Article
8.

UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program.

Lee S, Lee JW, Lee SK.

Dev Cell. 2012 Jan 17;22(1):25-37. doi: 10.1016/j.devcel.2011.11.009. Epub 2011 Dec 20.

PMID:
22192413
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.

Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18439-44. Epub 2007 Nov 14.

PMID:
18003914
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K.

Nature. 2007 Oct 11;449(7163):731-4. Epub 2007 Aug 22.

PMID:
17713478
[PubMed - indexed for MEDLINE]
11.

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y.

Cell. 2006 May 5;125(3):467-81. Epub 2006 Apr 6.

PMID:
16603238
[PubMed - indexed for MEDLINE]
Free Article
12.

The histone demethylase UTX enables RB-dependent cell fate control.

Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY.

Genes Dev. 2010 Feb 15;24(4):327-32. doi: 10.1101/gad.1882610. Epub 2010 Feb 1.

PMID:
20123895
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans.

Ni Z, Ebata A, Alipanahiramandi E, Lee SS.

Aging Cell. 2012 Apr;11(2):315-25. doi: 10.1111/j.1474-9726.2011.00785.x. Epub 2012 Jan 19.

PMID:
22212395
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line.

Bessler JB, Andersen EC, Villeneuve AM.

PLoS Genet. 2010 Jan 22;6(1):e1000830. doi: 10.1371/journal.pgen.1000830.

PMID:
20107519
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.

Kim JH, Sharma A, Dhar SS, Lee SH, Gu B, Chan CH, Lin HK, Lee MG.

Cancer Res. 2014 Mar 15;74(6):1705-17. doi: 10.1158/0008-5472.CAN-13-1896. Epub 2014 Feb 3.

PMID:
24491801
[PubMed - indexed for MEDLINE]
16.

Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.

Tie F, Banerjee R, Conrad PA, Scacheri PC, Harte PJ.

Mol Cell Biol. 2012 Jun;32(12):2323-34. doi: 10.1128/MCB.06392-11. Epub 2012 Apr 9.

PMID:
22493065
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Expression and significance of histone H3K27 demethylases in renal cell carcinoma.

Shen Y, Guo X, Wang Y, Qiu W, Chang Y, Zhang A, Duan X.

BMC Cancer. 2012 Oct 12;12:470. doi: 10.1186/1471-2407-12-470.

PMID:
23057811
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Histone methylation makes its mark on longevity.

Han S, Brunet A.

Trends Cell Biol. 2012 Jan;22(1):42-9. doi: 10.1016/j.tcb.2011.11.001. Epub 2011 Dec 15. Review.

PMID:
22177962
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.

Wang AH, Zare H, Mousavi K, Wang C, Moravec CE, Sirotkin HI, Ge K, Gutierrez-Cruz G, Sartorelli V.

EMBO J. 2013 Apr 17;32(8):1075-86. doi: 10.1038/emboj.2013.54. Epub 2013 Mar 15.

PMID:
23503590
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.

Miller SA, Mohn SE, Weinmann AS.

Mol Cell. 2010 Nov 24;40(4):594-605. doi: 10.1016/j.molcel.2010.10.028.

PMID:
21095589
[PubMed - indexed for MEDLINE]
Free PMC Article

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