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Results: 1 to 20 of 104

1.

Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice.

Teichert AE, Elalieh H, Elias PM, Welsh J, Bikle DD.

J Invest Dermatol. 2011 Nov;131(11):2289-97. doi: 10.1038/jid.2011.196. Epub 2011 Aug 4.

PMID:
21814234
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

1α,25(OH)2-dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway.

Jiang YJ, Teichert AE, Fong F, Oda Y, Bikle DD.

J Steroid Biochem Mol Biol. 2013 Jul;136:229-32. doi: 10.1016/j.jsbmb.2012.09.024. Epub 2012 Sep 28. Review.

PMID:
23026511
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The vitamin D receptor: a tumor suppressor in skin.

Bikle DD.

Discov Med. 2011 Jan;11(56):7-17.

PMID:
21276406
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis.

Ellison TI, Smith MK, Gilliam AC, MacDonald PN.

J Invest Dermatol. 2008 Oct;128(10):2508-17. doi: 10.1038/jid.2008.131. Epub 2008 May 29.

PMID:
18509362
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis.

Zinser GM, Sundberg JP, Welsh J.

Carcinogenesis. 2002 Dec;23(12):2103-9.

PMID:
12507934
[PubMed - indexed for MEDLINE]
Free Article
6.

Antitumoral effects of calcitriol in basal cell carcinomas involve inhibition of hedgehog signaling and induction of vitamin D receptor signaling and differentiation.

Uhmann A, Niemann H, Lammering B, Henkel C, Hess I, Nitzki F, Fritsch A, Prüfer N, Rosenberger A, Dullin C, Schraepler A, Reifenberger J, Schweyer S, Pietsch T, Strutz F, Schulz-Schaeffer W, Hahn H.

Mol Cancer Ther. 2011 Nov;10(11):2179-88. doi: 10.1158/1535-7163.MCT-11-0422. Epub 2011 Aug 30.

PMID:
21878656
[PubMed - indexed for MEDLINE]
Free Article
7.

Protective role of vitamin D signaling in skin cancer formation.

Bikle DD, Elalieh H, Welsh J, Oh D, Cleaver J, Teichert A.

J Steroid Biochem Mol Biol. 2013 Jul;136:271-9. doi: 10.1016/j.jsbmb.2012.09.021. Epub 2012 Oct 8. Review.

PMID:
23059470
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice.

Teichert A, Elalieh H, Bikle D.

J Cell Physiol. 2010 Nov;225(2):482-9. doi: 10.1002/jcp.22227.

PMID:
20458748
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues.

Zinser GM, Suckow M, Welsh J.

J Steroid Biochem Mol Biol. 2005 Oct;97(1-2):153-64. Epub 2005 Aug 18.

PMID:
16111884
[PubMed - indexed for MEDLINE]
10.

Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.

Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ.

Cancer Prev Res (Phila). 2010 Oct;3(10):1222-34. doi: 10.1158/1940-6207.CAPR-10-0082. Epub 2010 Sep 21.

PMID:
20858761
[PubMed - indexed for MEDLINE]
11.

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

Sachs N, Secades P, van Hulst L, Kreft M, Song JY, Sonnenberg A.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21468-73. doi: 10.1073/pnas.1204614110. Epub 2012 Dec 10.

PMID:
23236172
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation.

Capozza F, Williams TM, Schubert W, McClain S, Bouzahzah B, Sotgia F, Lisanti MP.

Am J Pathol. 2003 Jun;162(6):2029-39.

PMID:
12759258
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.

Indra AK, Castaneda E, Antal MC, Jiang M, Messaddeq N, Meng X, Loehr CV, Gariglio P, Kato S, Wahli W, Desvergne B, Metzger D, Chambon P.

J Invest Dermatol. 2007 May;127(5):1250-60. Epub 2007 Feb 15.

PMID:
17301838
[PubMed - indexed for MEDLINE]
Free Article
14.

A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesis.

Gu D, Fan Q, Zhang X, Xie J.

J Biol Chem. 2012 Nov 2;287(45):38356-66. doi: 10.1074/jbc.M112.377382. Epub 2012 Sep 19.

PMID:
22992748
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis.

Kim DJ, Angel JM, Sano S, DiGiovanni J.

Oncogene. 2009 Feb 19;28(7):950-60. doi: 10.1038/onc.2008.453. Epub 2009 Jan 12.

PMID:
19137019
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Vitamin D receptor as a master regulator of the c-MYC/MXD1 network.

Salehi-Tabar R, Nguyen-Yamamoto L, Tavera-Mendoza LE, Quail T, Dimitrov V, An BS, Glass L, Goltzman D, White JH.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18827-32. doi: 10.1073/pnas.1210037109. Epub 2012 Oct 29.

PMID:
23112173
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The 1,25-dihydroxyvitamin D3-independent actions of the vitamin D receptor in skin.

Dowd DR, MacDonald PN.

J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):317-21. doi: 10.1016/j.jsbmb.2010.03.072. Epub 2010 Apr 1. Review.

PMID:
20362670
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Evidence that vitamin D(3) promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice.

Biggs L, Yu C, Fedoric B, Lopez AF, Galli SJ, Grimbaldeston MA.

J Exp Med. 2010 Mar 15;207(3):455-63. doi: 10.1084/jem.20091725. Epub 2010 Mar 1.

PMID:
20194632
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog.

Fan H, Oro AE, Scott MP, Khavari PA.

Nat Med. 1997 Jul;3(7):788-92.

PMID:
9212109
[PubMed - indexed for MEDLINE]
20.

Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations.

Oda Y, Hu L, Bul V, Elalieh H, Reddy JK, Bikle DD.

J Invest Dermatol. 2012 Apr;132(4):1075-83. doi: 10.1038/jid.2011.430. Epub 2011 Dec 22.

PMID:
22189783
[PubMed - indexed for MEDLINE]
Free PMC Article

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