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Items: 1 to 20 of 117

1.

Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice.

Amireault P, Hatia S, Bayard E, Bernex F, Collet C, Callebert J, Launay JM, Hermine O, Schneider E, Mallet J, Dy M, Côté F.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13141-6. doi: 10.1073/pnas.1103964108. Epub 2011 Jul 25.

2.

Serotonin is a key factor for mouse red blood cell survival.

Amireault P, Bayard E, Launay JM, Sibon D, Le Van Kim C, Colin Y, Dy M, Hermine O, Côté F.

PLoS One. 2013 Dec 17;8(12):e83010. doi: 10.1371/journal.pone.0083010. eCollection 2013.

3.

Production of serotonin by tryptophan hydroxylase 1 and release via platelets contribute to allergic airway inflammation.

Dürk T, Duerschmied D, Müller T, Grimm M, Reuter S, Vieira RP, Ayata K, Cicko S, Sorichter S, Walther DJ, Virchow JC, Taube C, Idzko M.

Am J Respir Crit Care Med. 2013 Mar 1;187(5):476-85. doi: 10.1164/rccm.201208-1440OC. Epub 2013 Jan 17.

PMID:
23328530
4.

Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks.

Amireault P, Sibon D, Côté F.

ACS Chem Neurosci. 2013 Jan 16;4(1):64-71. doi: 10.1021/cn300154j. Epub 2012 Nov 7. Review.

5.

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.

Savelieva KV, Zhao S, Pogorelov VM, Rajan I, Yang Q, Cullinan E, Lanthorn TH.

PLoS One. 2008;3(10):e3301. doi: 10.1371/journal.pone.0003301. Epub 2008 Oct 15.

6.

Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.

Nakamura K, Sugawara Y, Sawabe K, Ohashi A, Tsurui H, Xiu Y, Ohtsuji M, Lin QS, Nishimura H, Hasegawa H, Hirose S.

J Neurosci. 2006 Jan 11;26(2):530-4.

7.

Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract.

Liu Q, Yang Q, Sun W, Vogel P, Heydorn W, Yu XQ, Hu Z, Yu W, Jonas B, Pineda R, Calderon-Gay V, Germann M, O'Neill E, Brommage R, Cullinan E, Platt K, Wilson A, Powell D, Sands A, Zambrowicz B, Shi ZC.

J Pharmacol Exp Ther. 2008 Apr;325(1):47-55. doi: 10.1124/jpet.107.132670. Epub 2008 Jan 11.

8.

[Abnormal cardiac activity in mice in the absence of peripheral serotonin synthesis].

Côté F, Fligny C, Mallet J, Vodjdani G.

J Soc Biol. 2004;198(1):7-17. Review. French.

PMID:
15146950
9.

Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.

Izikki M, Hanoun N, Marcos E, Savale L, Barlier-Mur AM, Saurini F, Eddahibi S, Hamon M, Adnot S.

Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1045-52. Epub 2007 Aug 3.

10.

Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.

Mosienko V, Beis D, Pasqualetti M, Waider J, Matthes S, Qadri F, Bader M, Alenina N.

Behav Brain Res. 2015 Jan 15;277:78-88. doi: 10.1016/j.bbr.2014.06.005. Epub 2014 Jun 11. Review.

PMID:
24928769
11.
12.

Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells.

Benninghoff J, Gritti A, Rizzi M, Lamorte G, Schloesser RJ, Schmitt A, Robel S, Genius J, Moessner R, Riederer P, Manji HK, Grunze H, Rujescu D, Moeller HJ, Lesch KP, Vescovi AL.

Neuropsychopharmacology. 2010 Mar;35(4):893-903. doi: 10.1038/npp.2009.181. Epub 2009 Dec 9.

13.

Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life.

Kriegebaum C, Song NN, Gutknecht L, Huang Y, Schmitt A, Reif A, Ding YQ, Lesch KP.

Neurochem Int. 2010 Nov;57(5):512-7. doi: 10.1016/j.neuint.2010.06.015. Epub 2010 Jul 3.

PMID:
20599453
14.

Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.

Gutknecht L, Araragi N, Merker S, Waider J, Sommerlandt FM, Mlinar B, Baccini G, Mayer U, Proft F, Hamon M, Schmitt AG, Corradetti R, Lanfumey L, Lesch KP.

PLoS One. 2012;7(8):e43157. doi: 10.1371/journal.pone.0043157. Epub 2012 Aug 17.

15.

A unique central tryptophan hydroxylase isoform.

Walther DJ, Bader M.

Biochem Pharmacol. 2003 Nov 1;66(9):1673-80.

PMID:
14563478
16.

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.

Gutknecht L, Kriegebaum C, Waider J, Schmitt A, Lesch KP.

Eur Neuropsychopharmacol. 2009 Apr;19(4):266-82. doi: 10.1016/j.euroneuro.2008.12.005. Epub 2009 Feb 1.

PMID:
19181488
17.

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.

Côté F, Thévenot E, Fligny C, Fromes Y, Darmon M, Ripoche MA, Bayard E, Hanoun N, Saurini F, Lechat P, Dandolo L, Hamon M, Mallet J, Vodjdani G.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13525-30. Epub 2003 Nov 3.

18.

Exogenous iron increases hemoglobin in beta-thalassemic mice.

Ginzburg YZ, Rybicki AC, Suzuka SM, Hall CB, Breuer W, Cabantchik ZI, Bouhassira EE, Fabry ME, Nagel RL.

Exp Hematol. 2009 Feb;37(2):172-83. doi: 10.1016/j.exphem.2008.10.004. Epub 2008 Dec 6.

PMID:
19059700
19.

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia.

Suragani RN, Cawley SM, Li R, Wallner S, Alexander MJ, Mulivor AW, Gardenghi S, Rivella S, Grinberg AV, Pearsall RS, Kumar R.

Blood. 2014 Jun 19;123(25):3864-72. doi: 10.1182/blood-2013-06-511238. Epub 2014 May 2.

20.

Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains.

Browne CA, Clarke G, Dinan TG, Cryan JF.

Neuropharmacology. 2011 Mar;60(4):683-91. doi: 10.1016/j.neuropharm.2010.11.020. Epub 2010 Dec 3.

PMID:
21130784
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