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Items: 1 to 20 of 145

1.

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, Licatalosi DD, Richter JD, Darnell RB.

Cell. 2011 Jul 22;146(2):247-61. doi: 10.1016/j.cell.2011.06.013.

2.

Molecular and cellular aspects of mental retardation in the Fragile X syndrome: from gene mutation/s to spine dysmorphogenesis.

De Rubeis S, Fernández E, Buzzi A, Di Marino D, Bagni C.

Adv Exp Med Biol. 2012;970:517-51. doi: 10.1007/978-3-7091-0932-8_23. Review.

PMID:
22351071
3.

The translation of translational control by FMRP: therapeutic targets for FXS.

Darnell JC, Klann E.

Nat Neurosci. 2013 Nov;16(11):1530-6. doi: 10.1038/nn.3379. Epub 2013 Apr 14. Review.

4.
5.

The state of synapses in fragile X syndrome.

Pfeiffer BE, Huber KM.

Neuroscientist. 2009 Oct;15(5):549-67. doi: 10.1177/1073858409333075. Epub 2009 Mar 26. Review.

6.

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses.

Zalfa F, Giorgi M, Primerano B, Moro A, Di Penta A, Reis S, Oostra B, Bagni C.

Cell. 2003 Feb 7;112(3):317-27.

7.

Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.

Schütt J, Falley K, Richter D, Kreienkamp HJ, Kindler S.

J Biol Chem. 2009 Sep 18;284(38):25479-87. doi: 10.1074/jbc.M109.042663. Epub 2009 Jul 28.

8.

Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].

El Fatimy R, Tremblay S, Dury AY, Solomon S, De Koninck P, Schrader JW, Khandjian EW.

PLoS One. 2012;7(6):e39338. doi: 10.1371/journal.pone.0039338. Epub 2012 Jun 21. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/05374d07-34cf-483f-80f4-ec87374cbeb6.

9.

Sunrise at the synapse: the FMRP mRNP shaping the synaptic interface.

Antar LN, Bassell GJ.

Neuron. 2003 Feb 20;37(4):555-8. Review.

11.

Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles.

Khandjian EW, Huot ME, Tremblay S, Davidovic L, Mazroui R, Bardoni B.

Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13357-62. Epub 2004 Aug 25.

12.
13.

Fmr1 deficiency promotes age-dependent alterations in the cortical synaptic proteome.

Tang B, Wang T, Wan H, Han L, Qin X, Zhang Y, Wang J, Yu C, Berton F, Francesconi W, Yates JR 3rd, Vanderklish PW, Liao L.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4697-706. doi: 10.1073/pnas.1502258112. Epub 2015 Aug 11.

PMID:
26307763
14.

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.

Darnell JC, Fraser CE, Mostovetsky O, Darnell RB.

Hum Mol Genet. 2009 Sep 1;18(17):3164-77. doi: 10.1093/hmg/ddp255. Epub 2009 Jun 1.

15.

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.

Bassell GJ, Warren ST.

Neuron. 2008 Oct 23;60(2):201-14. doi: 10.1016/j.neuron.2008.10.004. Review.

16.

Altered synaptic plasticity in a mouse model of fragile X mental retardation.

Huber KM, Gallagher SM, Warren ST, Bear MF.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7746-50.

17.

Lost once, the Fragile X Mental Retardation protein is now back onto brain polyribosomes.

Davidovic L, Huot ME, Khandjian EW.

RNA Biol. 2005 Jan;2(1):1-3. Epub 2005 Jan 15.

PMID:
17132937
18.

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.

Ronesi JA, Huber KM.

Sci Signal. 2008 Feb 5;1(5):pe6. doi: 10.1126/stke.15pe6. Review.

PMID:
18272470
19.

On BC1 RNA and the fragile X mental retardation protein.

Iacoangeli A, Rozhdestvensky TS, Dolzhanskaya N, Tournier B, Schütt J, Brosius J, Denman RB, Khandjian EW, Kindler S, Tiedge H.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):734-9. doi: 10.1073/pnas.0710991105. Epub 2008 Jan 9.

20.

c-Jun N-terminal kinase regulates mGluR-dependent expression of post-synaptic FMRP target proteins.

Schmit TL, Dowell JA, Maes ME, Wilhelm M.

J Neurochem. 2013 Dec;127(6):772-81. doi: 10.1111/jnc.12453. Epub 2013 Oct 24.

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