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Results: 1 to 20 of 169

1.

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53.

Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM.

Cell. 1990 Dec 21;63(6):1129-36.

PMID:
2175676
[PubMed - indexed for MEDLINE]
2.

Cellular targets of the oncoproteins encoded by the cancer associated human papillomaviruses.

Howley PM, Münger K, Romanczuk H, Scheffner M, Huibregtse JM.

Princess Takamatsu Symp. 1991;22:239-48. Review.

PMID:
1668886
[PubMed - indexed for MEDLINE]
3.
4.

Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins.

Scheffner M, Takahashi T, Huibregtse JM, Minna JD, Howley PM.

J Virol. 1992 Aug;66(8):5100-5.

PMID:
1321290
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

Talis AL, Huibregtse JM, Howley PM.

J Biol Chem. 1998 Mar 13;273(11):6439-45.

PMID:
9497376
[PubMed - indexed for MEDLINE]
Free Article
6.

Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins.

Scheffner M, Münger K, Huibregtse JM, Howley PM.

EMBO J. 1992 Jul;11(7):2425-31.

PMID:
1321031
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation.

Crook T, Tidy JA, Vousden KH.

Cell. 1991 Nov 1;67(3):547-56.

PMID:
1657399
[PubMed - indexed for MEDLINE]
8.

Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase.

Kao WH, Beaudenon SL, Talis AL, Huibregtse JM, Howley PM.

J Virol. 2000 Jul;74(14):6408-17.

PMID:
10864652
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.

Huibregtse JM, Scheffner M, Howley PM.

EMBO J. 1991 Dec;10(13):4129-35.

PMID:
1661671
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.

Mietz JA, Unger T, Huibregtse JM, Howley PM.

EMBO J. 1992 Dec;11(13):5013-20.

PMID:
1464323
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription.

Lechner MS, Mack DH, Finicle AB, Crook T, Vousden KH, Laimins LA.

EMBO J. 1992 Aug;11(8):3045-52. Erratum in: EMBO J 1992 Nov;11(11):4248.

PMID:
1379175
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Immunohistochemical co-expression of human papillomavirus type 16/18 transforming (E6) oncoprotein and p53 tumour suppressor gene proteins in oesophageal cancer.

Agarwal SK, Chatterji A, Bhambhani S, Sharma BK.

Indian J Exp Biol. 1998 Jun;36(6):559-63.

PMID:
9731468
[PubMed - indexed for MEDLINE]
14.

Functional inactivation of p73, a homolog of p53 tumor suppressor protein, by human papillomavirus E6 proteins.

Park JS, Kim EJ, Lee JY, Sin HS, Namkoong SE, Um SJ.

Int J Cancer. 2001 Mar 15;91(6):822-7.

PMID:
11275986
[PubMed - indexed for MEDLINE]
15.

Sensitivity of p53 lysine mutants to ubiquitin-directed degradation targeted by human papillomavirus E6.

Crook T, Ludwig RL, Marston NJ, Willkomm D, Vousden KH.

Virology. 1996 Mar 1;217(1):285-92.

PMID:
8599213
[PubMed - indexed for MEDLINE]
Free Article
16.

Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage.

Kessis TD, Slebos RJ, Nelson WG, Kastan MB, Plunkett BS, Han SM, Lorincz AT, Hedrick L, Cho KR.

Proc Natl Acad Sci U S A. 1993 May 1;90(9):3988-92.

PMID:
8387205
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

Huibregtse JM, Scheffner M, Howley PM.

Mol Cell Biol. 1993 Feb;13(2):775-84.

PMID:
8380895
[PubMed - indexed for MEDLINE]
Free PMC Article
18.
19.

Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products.

Münger K, Scheffner M, Huibregtse JM, Howley PM.

Cancer Surv. 1992;12:197-217. Review.

PMID:
1322242
[PubMed - indexed for MEDLINE]
20.

Inhibition of p53 DNA binding by human papillomavirus E6 proteins.

Lechner MS, Laimins LA.

J Virol. 1994 Jul;68(7):4262-73.

PMID:
8207801
[PubMed - indexed for MEDLINE]
Free PMC Article

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