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Results: 1 to 20 of 130

1.

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.

Evans DM, Spencer CC, Pointon JJ, Su Z, Harvey D, Kochan G, Oppermann U, Dilthey A, Pirinen M, Stone MA, Appleton L, Moutsianas L, Leslie S, Wordsworth T, Kenna TJ, Karaderi T, Thomas GP, Ward MM, Weisman MH, Farrar C, Bradbury LA, Danoy P, Inman RD, Maksymowych W, Gladman D, Rahman P; Spondyloarthritis Research Consortium of Canada (SPARCC), Morgan A, Marzo-Ortega H, Bowness P, Gaffney K, Gaston JS, Smith M, Bruges-Armas J, Couto AR, Sorrentino R, Paladini F, Ferreira MA, Xu H, Liu Y, Jiang L, Lopez-Larrea C, Díaz-Peña R, López-Vázquez A, Zayats T, Band G, Bellenguez C, Blackburn H, Blackwell JM, Bramon E, Bumpstead SJ, Casas JP, Corvin A, Craddock N, Deloukas P, Dronov S, Duncanson A, Edkins S, Freeman C, Gillman M, Gray E, Gwilliam R, Hammond N, Hunt SE, Jankowski J, Jayakumar A, Langford C, Liddle J, Markus HS, Mathew CG, McCann OT, McCarthy MI, Palmer CN, Peltonen L, Plomin R, Potter SC, Rautanen A, Ravindrarajah R, Ricketts M, Samani N, Sawcer SJ, Strange A, Trembath RC, Viswanathan AC, Waller M, Weston P, Whittaker P, Widaa S, Wood NW, McVean G, Reveille JD, Wordsworth BP, Brown MA, Donnelly P; Australo-Anglo-American Spondyloarthritis Consortium (TASC); Wellcome Trust Case Control Consortium 2 (WTCCC2).

Nat Genet. 2011 Jul 10;43(8):761-7. doi: 10.1038/ng.873. Erratum in: Nat Genet. 2011 Sep;43(9):919. Opperman, Udo [corrected to Oppermann, Udo]; Moutsianis, Loukas [corrected to Moutsianas, Loukas].

PMID:
21743469
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Association of ankylosing spondylitis with HLA-B27 and ERAP1: pathogenic role of antigenic peptide.

Chen B, Li D, Xu W.

Med Hypotheses. 2013 Jan;80(1):36-8. doi: 10.1016/j.mehy.2012.10.003. Epub 2012 Nov 1.

PMID:
23123136
[PubMed - indexed for MEDLINE]
3.

ERAP1 in ankylosing spondylitis: genetics, biology and pathogenetic role.

Alvarez-Navarro C, López de Castro JA.

Curr Opin Rheumatol. 2013 Jul;25(4):419-25. doi: 10.1097/BOR.0b013e328362042f. Review.

PMID:
23656713
[PubMed - indexed for MEDLINE]
4.

Combined effects of ankylosing spondylitis-associated ERAP1 polymorphisms outside the catalytic and peptide-binding sites on the processing of natural HLA-B27 ligands.

Martín-Esteban A, Gómez-Molina P, Sanz-Bravo A, López de Castro JA.

J Biol Chem. 2014 Feb 14;289(7):3978-90. doi: 10.1074/jbc.M113.529610. Epub 2013 Dec 18.

PMID:
24352655
[PubMed - indexed for MEDLINE]
5.

Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo.

García-Medel N, Sanz-Bravo A, Van Nguyen D, Galocha B, Gómez-Molina P, Martín-Esteban A, Alvarez-Navarro C, de Castro JA.

Mol Cell Proteomics. 2012 Nov;11(11):1416-29. doi: 10.1074/mcp.M112.019588. Epub 2012 Aug 23.

PMID:
22918227
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

ERAP1 and ankylosing spondylitis.

Keidel S, Chen L, Pointon J, Wordsworth P.

Curr Opin Immunol. 2013 Feb;25(1):97-102. doi: 10.1016/j.coi.2012.11.002. Review.

PMID:
23452840
[PubMed - indexed for MEDLINE]
7.

Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis.

Haroon N, Tsui FW, Uchanska-Ziegler B, Ziegler A, Inman RD.

Ann Rheum Dis. 2012 Apr;71(4):589-95. doi: 10.1136/annrheumdis-2011-200347. Epub 2012 Feb 21. Erratum in: Ann Rheum Dis. 2012 Jul;71(7):1264.

PMID:
22355039
[PubMed - indexed for MEDLINE]
8.

Endoplasmic reticulum aminopeptidase 1 and interleukin-23 receptor in ankylosing spondylitis.

Haroon N.

Curr Rheumatol Rep. 2012 Oct;14(5):383-9. doi: 10.1007/s11926-012-0268-0. Review.

PMID:
22782541
[PubMed - indexed for MEDLINE]
9.

ERAP1 structure, function and pathogenetic role in ankylosing spondylitis and other MHC-associated diseases.

Alvarez-Navarro C, López de Castro JA.

Mol Immunol. 2014 Jan;57(1):12-21. doi: 10.1016/j.molimm.2013.06.012. Epub 2013 Jul 31. Review.

PMID:
23916068
[PubMed - indexed for MEDLINE]
10.

Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens.

Seregin SS, Rastall DP, Evnouchidou I, Aylsworth CF, Quiroga D, Kamal RP, Godbehere-Roosa S, Blum CF, York IA, Stratikos E, Amalfitano A.

Autoimmunity. 2013 Dec;46(8):497-508. doi: 10.3109/08916934.2013.819855. Epub 2013 Sep 13.

PMID:
24028501
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.

Chen L, Fischer R, Peng Y, Reeves E, McHugh K, Ternette N, Hanke T, Dong T, Elliott T, Shastri N, Kollnberger S, James E, Kessler B, Bowness P.

Arthritis Rheumatol. 2014 Feb;66(2):284-94. doi: 10.1002/art.38249.

PMID:
24504800
[PubMed - indexed for MEDLINE]
12.

ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis.

Wang CM, Ho HH, Chang SW, Wu YJ, Lin JC, Chang PY, Wu J, Chen JY.

Arthritis Res Ther. 2012 May 25;14(3):R125. doi: 10.1186/ar3855.

PMID:
22632381
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential.

Haroon N, Inman RD.

Nat Rev Rheumatol. 2010 Aug;6(8):461-7. doi: 10.1038/nrrheum.2010.85. Epub 2010 Jun 8. Review.

PMID:
20531381
[PubMed - indexed for MEDLINE]
14.

Polymorphism of HLA-B27: 105 subtypes currently known.

Khan MA.

Curr Rheumatol Rep. 2013 Oct;15(10):362. doi: 10.1007/s11926-013-0362-y. Review.

PMID:
23990399
[PubMed - indexed for MEDLINE]
15.

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals.

Bettencourt BF, Rocha FL, Alves H, Amorim R, Caetano-Lopes J, Vieira-Sousa E, Pimentel-Santos F, Lima M, Porto G, Branco JC, Fonseca JE, Bruges-Armas J.

Rheumatology (Oxford). 2013 Dec;52(12):2168-76. doi: 10.1093/rheumatology/ket269. Epub 2013 Sep 17.

PMID:
24046467
[PubMed - indexed for MEDLINE]
16.

Functional variants of ERAP1 gene are associated with HLA-B27 positive spondyloarthritis.

Cherciu M, Popa LO, Bojinca M, Dutescu MI, Bojinca V, Bara C, Popa OM.

Tissue Antigens. 2013 Sep;82(3):192-6. doi: 10.1111/tan.12158. Epub 2013 Jun 26.

PMID:
23800305
[PubMed - indexed for MEDLINE]
17.

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.

International Genetics of Ankylosing Spondylitis Consortium (IGAS), Cortes A, Hadler J, Pointon JP, Robinson PC, Karaderi T, Leo P, Cremin K, Pryce K, Harris J, Lee S, Joo KB, Shim SC, Weisman M, Ward M, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Jiang L, Liu Y, Wu X, Bradbury LA, Elewaut D, Burgos-Vargas R, Stebbings S, Appleton L, Farrah C, Lau J, Kenna TJ, Haroon N, Ferreira MA, Yang J, Mulero J, Fernandez-Sueiro JL, Gonzalez-Gay MA, Lopez-Larrea C, Deloukas P, Donnelly P; Australo-Anglo-American Spondyloarthritis Consortium (TASC); Groupe Française d'Etude Génétique des Spondylarthrites (GFEGS); Nord-Trøndelag Health Study (HUNT); Spondyloarthritis Research Consortium of Canada (SPARCC); Wellcome Trust Case Control Consortium 2 (WTCCC2), Bowness P, Gafney K, Gaston H, Gladman DD, Rahman P, Maksymowych WP, Xu H, Crusius JB, van der Horst-Bruinsma IE, Chou CT, Valle-Oñate R, Romero-Sánchez C, Hansen IM, Pimentel-Santos FM, Inman RD, Videm V, Martin J, Breban M, Reveille JD, Evans DM, Kim TH, Wordsworth BP, Brown MA.

Nat Genet. 2013 Jul;45(7):730-8. doi: 10.1038/ng.2667. Epub 2013 Jun 9.

PMID:
23749187
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis.

Jadon D, Tillett W, Wallis D, Cavill C, Bowes J, Waldron N, Dixon A, Sengupta R, Barton A, Korendowych E, McHugh NJ.

Rheumatology (Oxford). 2013 Feb;52(2):261-6. doi: 10.1093/rheumatology/kes254. Epub 2012 Oct 23.

PMID:
23093722
[PubMed - indexed for MEDLINE]
19.

Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort.

Campbell EC, Fettke F, Bhat S, Morley KD, Powis SJ.

Immunology. 2011 Jul;133(3):379-85. doi: 10.1111/j.1365-2567.2011.03453.x. Epub 2011 May 17.

PMID:
21574996
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The genetics of ankylosing spondylitis and axial spondyloarthritis.

Robinson PC, Brown MA.

Rheum Dis Clin North Am. 2012 Aug;38(3):539-53. doi: 10.1016/j.rdc.2012.08.018. Epub 2012 Sep 19. Review.

PMID:
23083754
[PubMed - indexed for MEDLINE]

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