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Items: 1 to 20 of 92

1.

Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.

Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF.

J Neurosci. 2011 Jul 6;31(27):10067-75. doi: 10.1523/JNEUROSCI.6730-10.2011.

2.

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.

Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O.

Nat Neurosci. 2005 Jul;8(7):858-9.

PMID:
15965471
3.

Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine.

Yang JN, Chen JF, Fredholm BB.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1141-9. doi: 10.1152/ajpheart.00754.2008. Epub 2009 Feb 13.

4.

Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation.

Quarta D, Borycz J, Solinas M, Patkar K, Hockemeyer J, Ciruela F, Lluis C, Franco R, Woods AS, Goldberg SR, Ferré S.

J Neurochem. 2004 Nov;91(4):873-80.

5.

Potentiation of amphetamine-mediated responses in caffeine-sensitized rats involves modifications in A2A receptors and zif-268 mRNAs in striatal neurons.

Tronci E, Simola N, Carta AR, De Luca MA, Morelli M.

J Neurochem. 2006 Aug;98(4):1078-89. Epub 2006 Jun 12.

6.
7.

Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice.

Bilbao A, Cippitelli A, Martín AB, Granado N, Ortiz O, Bezard E, Chen JF, Navarro M, Rodríguez de Fonseca F, Moratalla R.

Psychopharmacology (Berl). 2006 Apr;185(2):160-8. Epub 2006 Feb 10.

PMID:
16470403
9.

Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors.

Zahniser NR, Simosky JK, Mayfield RD, Negri CA, Hanania T, Larson GA, Kelly MA, Grandy DK, Rubinstein M, Low MJ, Fredholm BB.

J Neurosci. 2000 Aug 15;20(16):5949-57. Erratum in: J Neurosci 2000 Nov 1;20(21):1a.

10.

Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens.

Solinas M, Ferré S, You ZB, Karcz-Kubicha M, Popoli P, Goldberg SR.

J Neurosci. 2002 Aug 1;22(15):6321-4.

11.

Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects.

Sturgess JE, Ting-A-Kee RA, Podbielski D, Sellings LH, Chen JF, van der Kooy D.

Eur J Neurosci. 2010 Jul;32(1):143-54. doi: 10.1111/j.1460-9568.2010.07247.x. Epub 2010 Jun 22.

12.

Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling.

Yu L, Coelho JE, Zhang X, Fu Y, Tillman A, Karaoz U, Fredholm BB, Weng Z, Chen JF.

Physiol Genomics. 2009 May 13;37(3):199-210. doi: 10.1152/physiolgenomics.90353.2008. Epub 2009 Mar 3.

13.

The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice.

Chen JF, Moratalla R, Impagnatiello F, Grandy DK, Cuellar B, Rubinstein M, Beilstein MA, Hackett E, Fink JS, Low MJ, Ongini E, Schwarzschild MA.

Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1970-5.

14.

Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors.

Farrar AM, Segovia KN, Randall PA, Nunes EJ, Collins LE, Stopper CM, Port RG, Hockemeyer J, Müller CE, Correa M, Salamone JD.

Neuroscience. 2010 Apr 14;166(4):1056-67. doi: 10.1016/j.neuroscience.2009.12.056. Epub 2010 Jan 20.

PMID:
20096336
15.
16.

Caffeine as a psychomotor stimulant: mechanism of action.

Fisone G, Borgkvist A, Usiello A.

Cell Mol Life Sci. 2004 Apr;61(7-8):857-72. Review.

PMID:
15095008
17.

Effect of subtype-selective adenosine receptor antagonists on basal or haloperidol-regulated striatal function: studies of exploratory locomotion and c-Fos immunoreactivity in outbred and A(2A)R KO mice.

Pardo M, López-Cruz L, Valverde O, Ledent C, Baqi Y, Müller CE, Salamone JD, Correa M.

Behav Brain Res. 2013 Jun 15;247:217-26. doi: 10.1016/j.bbr.2013.03.035. Epub 2013 Apr 1.

PMID:
23557694
18.

The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors.

El Yacoubi M, Ledent C, Ménard JF, Parmentier M, Costentin J, Vaugeois JM.

Br J Pharmacol. 2000 Apr;129(7):1465-73.

19.

The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal.

Qiu MH, Liu W, Qu WM, Urade Y, Lu J, Huang ZL.

PLoS One. 2012;7(9):e45471. doi: 10.1371/journal.pone.0045471. Epub 2012 Sep 19.

20.
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