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Items: 1 to 20 of 205

1.

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells.

Yahata T, Takanashi T, Muguruma Y, Ibrahim AA, Matsuzawa H, Uno T, Sheng Y, Onizuka M, Ito M, Kato S, Ando K.

Blood. 2011 Sep 15;118(11):2941-50. doi: 10.1182/blood-2011-01-330050. Epub 2011 Jul 6.

2.

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.

Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T.

Nat Med. 2006 Apr;12(4):446-51. Epub 2006 Mar 26. Erratum in: Nat Med. 2010 Jan;16(1):129.

PMID:
16565722
3.

Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells.

Wang Y, Liu L, Pazhanisamy SK, Li H, Meng A, Zhou D.

Free Radic Biol Med. 2010 Jan 15;48(2):348-56. doi: 10.1016/j.freeradbiomed.2009.11.005. Epub 2009 Dec 2.

4.

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109. Epub 2012 May 18.

5.

Maintenance of genomic integrity in hematopoietic stem cells.

Naka K, Hirao A.

Int J Hematol. 2011 Apr;93(4):434-9. doi: 10.1007/s12185-011-0793-z. Epub 2011 Mar 9. Review.

PMID:
21384097
6.

Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence.

Zhang X, Sejas DP, Qiu Y, Williams DA, Pang Q.

J Cell Sci. 2007 May 1;120(Pt 9):1572-83. Epub 2007 Apr 3.

7.

Bmi1 confers resistance to oxidative stress on hematopoietic stem cells.

Nakamura S, Oshima M, Yuan J, Saraya A, Miyagi S, Konuma T, Yamazaki S, Osawa M, Nakauchi H, Koseki H, Iwama A.

PLoS One. 2012;7(5):e36209. doi: 10.1371/journal.pone.0036209. Epub 2012 May 11.

8.

The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity.

Campbell CJ, Lee JB, Levadoux-Martin M, Wynder T, Xenocostas A, Leber B, Bhatia M.

Blood. 2010 Sep 2;116(9):1433-42. doi: 10.1182/blood-2009-12-258095. Epub 2010 Jun 4.

9.

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA.

Blood. 2010 May 20;115(20):4030-8. doi: 10.1182/blood-2009-09-241000. Epub 2010 Mar 30.

10.

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.

Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Hamaguchi I, Nomiyama K, Hosokawa K, Sakurada K, Nakagata N, Ikeda Y, Mak TW, Suda T.

Nature. 2004 Oct 21;431(7011):997-1002.

PMID:
15496926
12.

Depletion of Dnmt1-associated protein 1 triggers DNA damage and compromises the proliferative capacity of hematopoietic stem cells.

Koizumi T, Negishi M, Nakamura S, Oguro H, Satoh K, Ichinose M, Iwama A.

Int J Hematol. 2010 May;91(4):611-9. doi: 10.1007/s12185-010-0563-3. Epub 2010 Apr 14.

PMID:
20387133
13.

The hematopoietic stem cell niche: low in oxygen but a nice place to be.

Eliasson P, J├Ânsson JI.

J Cell Physiol. 2010 Jan;222(1):17-22. doi: 10.1002/jcp.21908. Review.

PMID:
19725055
14.

Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation.

Hoggatt J, Singh P, Sampath J, Pelus LM.

Blood. 2009 May 28;113(22):5444-55. doi: 10.1182/blood-2009-01-201335. Epub 2009 Mar 26.

15.

Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells.

Naka K, Muraguchi T, Hoshii T, Hirao A.

Antioxid Redox Signal. 2008 Nov;10(11):1883-94. doi: 10.1089/ars.2008.2114. Review.

PMID:
18627347
16.

Hematopoietic stem cell aging and self-renewal.

Dykstra B, de Haan G.

Cell Tissue Res. 2008 Jan;331(1):91-101. Epub 2007 Nov 16. Review.

PMID:
18008087
18.

Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice.

Singh KP, Bennett JA, Casado FL, Walrath JL, Welle SL, Gasiewicz TA.

Stem Cells Dev. 2014 Jan 15;23(2):95-106. doi: 10.1089/scd.2013.0346. Epub 2013 Oct 19.

19.

Engraftment of human hematopoietic stem cells is more efficient in female NOD/SCID/IL-2Rgc-null recipients.

Notta F, Doulatov S, Dick JE.

Blood. 2010 May 6;115(18):3704-7. doi: 10.1182/blood-2009-10-249326. Epub 2010 Mar 5.

20.

Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.

Faiola B, Fuller ES, Wong VA, Pluta L, Abernethy DJ, Rose J, Recio L.

Stem Cells. 2004;22(5):750-8.

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