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Items: 1 to 20 of 141

1.

Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1.

Uribarri J, Cai W, Ramdas M, Goodman S, Pyzik R, Chen X, Zhu L, Striker GE, Vlassara H.

Diabetes Care. 2011 Jul;34(7):1610-6. doi: 10.2337/dc11-0091.

2.

Suppression of native defense mechanisms, SIRT1 and PPARγ, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases.

Uribarri J, Cai W, Pyzik R, Goodman S, Chen X, Zhu L, Ramdas M, Striker GE, Vlassara H.

Amino Acids. 2014 Feb;46(2):301-9. doi: 10.1007/s00726-013-1502-4. Epub 2013 May 1.

3.

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.

Cai W, Ramdas M, Zhu L, Chen X, Striker GE, Vlassara H.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15888-93. Epub 2012 Aug 20.

4.

Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1.

Vlassara H, Cai W, Goodman S, Pyzik R, Yong A, Chen X, Zhu L, Neade T, Beeri M, Silverman JM, Ferrucci L, Tansman L, Striker GE, Uribarri J.

J Clin Endocrinol Metab. 2009 Nov;94(11):4483-91. doi: 10.1210/jc.2009-0089. Epub 2009 Oct 9.

5.

Advanced glycation end product receptor-1 transgenic mice are resistant to inflammation, oxidative stress, and post-injury intimal hyperplasia.

Torreggiani M, Liu H, Wu J, Zheng F, Cai W, Striker G, Vlassara H.

Am J Pathol. 2009 Oct;175(4):1722-32. doi: 10.2353/ajpath.2009.090138. Epub 2009 Sep 24.

6.

Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression.

Cai W, He JC, Zhu L, Chen X, Wallenstein S, Striker GE, Vlassara H.

Am J Pathol. 2007 Jun;170(6):1893-902.

7.

AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.

Cai W, He JC, Zhu L, Chen X, Striker GE, Vlassara H.

Am J Physiol Cell Physiol. 2008 Jan;294(1):C145-52. Epub 2007 Nov 21.

8.

Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.

Cai W, Uribarri J, Zhu L, Chen X, Swamy S, Zhao Z, Grosjean F, Simonaro C, Kuchel GA, Schnaider-Beeri M, Woodward M, Striker GE, Vlassara H.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4940-5. doi: 10.1073/pnas.1316013111. Epub 2014 Feb 24.

9.

Identifying advanced glycation end products as a major source of oxidants in aging: implications for the management and/or prevention of reduced renal function in elderly persons.

Vlassara H, Uribarri J, Ferrucci L, Cai W, Torreggiani M, Post JB, Zheng F, Striker GE.

Semin Nephrol. 2009 Nov;29(6):594-603. doi: 10.1016/j.semnephrol.2009.07.013.

PMID:
20006791
10.

Serum advanced glycation end products (AGEs) are associated with insulin resistance.

Tan KC, Shiu SW, Wong Y, Tam X.

Diabetes Metab Res Rev. 2011 Jul;27(5):488-92. doi: 10.1002/dmrr.1188.

PMID:
21337488
11.

Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan.

Cai W, He JC, Zhu L, Chen X, Zheng F, Striker GE, Vlassara H.

Am J Pathol. 2008 Aug;173(2):327-36. doi: 10.2353/ajpath.2008.080152. Epub 2008 Jul 3.

12.

AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.

Cai W, Torreggiani M, Zhu L, Chen X, He JC, Striker GE, Vlassara H.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C624-34. doi: 10.1152/ajpcell.00463.2009. Epub 2009 Dec 2.

13.

AGE restriction in diabetes mellitus: a paradigm shift.

Vlassara H, Striker GE.

Nat Rev Endocrinol. 2011 May 24;7(9):526-39. doi: 10.1038/nrendo.2011.74. Review.

14.

Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease.

Vlassara H, Uribarri J, Cai W, Goodman S, Pyzik R, Post J, Grosjean F, Woodward M, Striker GE.

Clin J Am Soc Nephrol. 2012 Jun;7(6):934-42. doi: 10.2215/CJN.12891211. Epub 2012 Mar 29.

15.

Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor.

Cai W, He JC, Zhu L, Lu C, Vlassara H.

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13801-6. Epub 2006 Sep 5.

16.

Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo.

Lee BH, Hsu WH, Chang YY, Kuo HF, Hsu YW, Pan TM.

Free Radic Biol Med. 2012 Dec 1;53(11):2008-16. doi: 10.1016/j.freeradbiomed.2012.09.025. Epub 2012 Sep 26.

PMID:
23022408
17.

Advanced glycation endproducts in food and their effects on health.

Poulsen MW, Hedegaard RV, Andersen JM, de Courten B, Bügel S, Nielsen J, Skibsted LH, Dragsted LO.

Food Chem Toxicol. 2013 Oct;60:10-37. doi: 10.1016/j.fct.2013.06.052. Epub 2013 Jul 16. Review.

PMID:
23867544
18.

Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.

Yubero-Serrano EM, Woodward M, Poretsky L, Vlassara H, Striker GE; AGE-less Study Group.

Clin J Am Soc Nephrol. 2015 May 7;10(5):759-66. doi: 10.2215/CJN.07750814. Epub 2015 Feb 20.

19.

Advanced glycation end product homeostasis: exogenous oxidants and innate defenses.

Vlassara H, Uribarri J, Cai W, Striker G.

Ann N Y Acad Sci. 2008 Apr;1126:46-52. doi: 10.1196/annals.1433.055.

PMID:
18448795
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