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Items: 1 to 20 of 114

1.

Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest.

Ganley IG, Wong PM, Gammoh N, Jiang X.

Mol Cell. 2011 Jun 24;42(6):731-43. doi: 10.1016/j.molcel.2011.04.024.

2.

Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy.

Ganley IG, Wong PM, Jiang X.

Autophagy. 2011 Nov;7(11):1397-9. doi: 10.4161/auto.7.11.17651. Epub 2011 Nov 1.

PMID:
21921693
3.

Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH.

Lu Y, Hao BX, Graeff R, Wong CW, Wu WT, Yue J.

J Biol Chem. 2013 Aug 16;288(33):24247-63. doi: 10.1074/jbc.M113.484253. Epub 2013 Jul 8.

4.

Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7.

Hu D, Wu J, Wang W, Mu M, Zhao R, Xu X, Chen Z, Xiao J, Hu F, Yang Y, Zhang R.

Biochem Biophys Res Commun. 2015 May 29;461(2):401-7. doi: 10.1016/j.bbrc.2015.04.051. Epub 2015 Apr 18.

PMID:
25896765
5.

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.

McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, Pierre P, Dikic I.

Mol Cell. 2015 Jan 8;57(1):39-54. doi: 10.1016/j.molcel.2014.11.006. Epub 2014 Dec 11.

6.

A Vps21 endocytic module regulates autophagy.

Chen Y, Zhou F, Zou S, Yu S, Li S, Li D, Song J, Li H, He Z, Hu B, Björn LO, Lipatova Z, Liang Y, Xie Z, Segev N.

Mol Biol Cell. 2014 Oct 15;25(20):3166-77. doi: 10.1091/mbc.E14-04-0917. Epub 2014 Aug 20.

7.

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, Jung JU.

Nat Cell Biol. 2008 Jul;10(7):776-87. doi: 10.1038/ncb1740. Epub 2008 Jun 15.

8.
9.

Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes.

Zhao T, Huang X, Han L, Wang X, Cheng H, Zhao Y, Chen Q, Chen J, Cheng H, Xiao R, Zheng M.

J Biol Chem. 2012 Jul 6;287(28):23615-25. doi: 10.1074/jbc.M112.379164. Epub 2012 May 22.

10.

Reciprocal effects of rab7 deletion in activated and neglected T cells.

Roy SG, Stevens MW, So L, Edinger AL.

Autophagy. 2013 Jul;9(7):1009-23. doi: 10.4161/auto.24468. Epub 2013 Apr 15.

11.

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells.

Gutierrez MG, Munafó DB, Berón W, Colombo MI.

J Cell Sci. 2004 Jun 1;117(Pt 13):2687-97. Epub 2004 May 11.

12.

CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression.

Yan CH, Li Y, Tian XX, Zhu N, Song HX, Zhang J, Sun MY, Han YL.

Biochim Biophys Acta. 2015 Feb;1852(2):353-64.

PMID:
25774384
13.

Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.

Choi YJ, Park YJ, Park JY, Jeong HO, Kim DH, Ha YM, Kim JM, Song YM, Heo HS, Yu BP, Chun P, Moon HR, Chung HY.

PLoS One. 2012;7(8):e43418. doi: 10.1371/journal.pone.0043418. Epub 2012 Aug 22. Erratum in: PLoS One. 2013;8(1). doi:10.1371/annotation/e3163ad5-f3d8-4a21-b3e1-f2033a76f9db.

14.

Lysosomal targeting of phafin1 mediated by Rab7 induces autophagosome formation.

Lin WJ, Yang CY, Li LL, Yi YH, Chen KW, Lin YC, Liu CC, Lin CH.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):35-42. doi: 10.1016/j.bbrc.2011.11.043. Epub 2011 Nov 15.

PMID:
22115783
15.

Modulation of intracellular calcium homeostasis blocks autophagosome formation.

Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Sætre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, Simonsen A, Mills IG.

Autophagy. 2013 Oct;9(10):1475-90. doi: 10.4161/auto.25900. Epub 2013 Aug 13.

PMID:
23970164
16.

COP9 signalosome regulates autophagosome maturation.

Su H, Li F, Ranek MJ, Wei N, Wang X.

Circulation. 2011 Nov 8;124(19):2117-28. doi: 10.1161/CIRCULATIONAHA.111.048934. Epub 2011 Oct 10.

17.

The TBC/RabGAP Armus coordinates Rac1 and Rab7 functions during autophagy.

Carroll B, Mohd-Naim N, Maximiano F, Frasa MA, McCormack J, Finelli M, Thoresen SB, Perdios L, Daigaku R, Francis RE, Futter C, Dikic I, Braga VM.

Dev Cell. 2013 Apr 15;25(1):15-28. doi: 10.1016/j.devcel.2013.03.005. Epub 2013 Apr 4.

18.

Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum.

Sakaki K, Wu J, Kaufman RJ.

J Biol Chem. 2008 May 30;283(22):15370-80. doi: 10.1074/jbc.M710209200. Epub 2008 Mar 20.

19.
20.

Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation.

Toyofuku T, Morimoto K, Sasawatari S, Kumanogoh A.

Mol Cell Biol. 2015 Sep 1;35(17):3044-58. doi: 10.1128/MCB.00085-15. Epub 2015 Jun 22.

PMID:
26100023
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