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Items: 1 to 20 of 108


Transcriptional down-regulation of Brca1 and E-cadherin by CtBP1 in breast cancer.

Deng Y, Deng H, Liu J, Han G, Malkoski S, Liu B, Zhao R, Wang XJ, Zhang Q.

Mol Carcinog. 2012 Jun;51(6):500-7. doi: 10.1002/mc.20813. Epub 2011 Jun 16.


Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1.

Deng Y, Liu J, Han G, Lu SL, Wang SY, Malkoski S, Tan AC, Deng C, Wang XJ, Zhang Q.

Oncogene. 2010 Dec 16;29(50):6603-8. doi: 10.1038/onc.2010.406. Epub 2010 Sep 6.


CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1.

Deng H, Liu J, Deng Y, Han G, Shellman YG, Robinson SE, Tentler JJ, Robinson WA, Norris DA, Wang XJ, Zhang Q.

J Invest Dermatol. 2013 May;133(5):1294-301. doi: 10.1038/jid.2012.487. Epub 2013 Jan 10.


Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance.

Birts CN, Harding R, Soosaipillai G, Halder T, Azim-Araghi A, Darley M, Cutress RI, Bateman AC, Blaydes JP.

Biol Cell. 2010 Jan;103(1):1-19. doi: 10.1042/BC20100067.


MicroRNA-137 targets carboxyl-terminal binding protein 1 in melanoma cell lines.

Deng Y, Deng H, Bi F, Liu J, Bemis LT, Norris D, Wang XJ, Zhang Q.

Int J Biol Sci. 2011 Jan 27;7(1):133-7.


Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.

Huang W, Zhang Y, Varambally S, Chinnaiyan AM, Banerjee M, Merajver SD, Kleer CG.

Am J Pathol. 2008 Apr;172(4):893-904. doi: 10.2353/ajpath.2008.070899. Epub 2008 Mar 5.


BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cells.

Yang S, Du J, Wang Z, Yuan W, Qiao Y, Zhang M, Zhang J, Gao S, Yin J, Sun B, Zhu T.

BMC Cancer. 2007 Nov 13;7:211.


CtBP1 is involved in epithelial-mesenchymal transition and is a potential therapeutic target for hepatocellular carcinoma.

Zhang XL, Huang CX, Zhang J, Inoue A, Zeng SE, Xiao SJ.

Oncol Rep. 2013 Aug;30(2):809-14. doi: 10.3892/or.2013.2537. Epub 2013 Jun 11.


UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.

Jin W, Chen L, Chen Y, Xu SG, Di GH, Yin WJ, Wu J, Shao ZM.

Breast Cancer Res Treat. 2010 Sep;123(2):359-73. doi: 10.1007/s10549-009-0652-2. Epub 2009 Nov 27.


BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer.

Gorski JJ, James CR, Quinn JE, Stewart GE, Staunton KC, Buckley NE, McDyer FA, Kennedy RD, Wilson RH, Mullan PB, Harkin DP.

Breast Cancer Res Treat. 2010 Aug;122(3):721-31. doi: 10.1007/s10549-009-0565-0. Epub 2009 Oct 31.


CtBP1 overexpression in keratinocytes perturbs skin homeostasis.

Deng H, Li F, Li H, Deng Y, Liu J, Wang D, Han G, Wang XJ, Zhang Q.

J Invest Dermatol. 2014 May;134(5):1323-31. doi: 10.1038/jid.2013.504. Epub 2013 Nov 26.


The SLUG zinc-finger protein represses E-cadherin in breast cancer.

Hajra KM, Chen DY, Fearon ER.

Cancer Res. 2002 Mar 15;62(6):1613-8.


Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin.

Shah P, Gau Y, Sabnis G.

Breast Cancer Res Treat. 2014 Jan;143(1):99-111. doi: 10.1007/s10549-013-2784-7. Epub 2013 Dec 5.


Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene.

Alpatov R, Munguba GC, Caton P, Joo JH, Shi Y, Shi Y, Hunt ME, Sugrue SP.

Mol Cell Biol. 2004 Dec;24(23):10223-35.


Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin.

Li H, Sekine M, Tung N, Avraham HK.

Mol Cancer Res. 2010 Mar;8(3):407-20. doi: 10.1158/1541-7786.MCR-09-0403. Epub 2010 Mar 9.


BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2.

May T, Yang J, Shoni M, Liu S, He H, Gali R, Ng SK, Crum C, Berkowitz RS, Ng SW.

Neoplasia. 2013 Jun;15(6):600-8.


Estrogen-mediated down-regulation of E-cadherin in breast cancer cells.

Oesterreich S, Deng W, Jiang S, Cui X, Ivanova M, Schiff R, Kang K, Hadsell DL, Behrens J, Lee AV.

Cancer Res. 2003 Sep 1;63(17):5203-8.


Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region.

Magdinier F, Ribieras S, Lenoir GM, Frappart L, Dante R.

Oncogene. 1998 Dec 17;17(24):3169-76.


Loss of full length CtBP1 expression enhances the invasive potential of human melanoma.

Winklmeier A, Poser I, Hoek KS, Bosserhoff AK.

BMC Cancer. 2009 Feb 12;9:52. doi: 10.1186/1471-2407-9-52.

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