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Results: 1 to 20 of 112

1.

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Zhang J, Mullighan CG, Harvey RC, Wu G, Chen X, Edmonson M, Buetow KH, Carroll WL, Chen IM, Devidas M, Gerhard DS, Loh ML, Reaman GH, Relling MV, Camitta BM, Bowman WP, Smith MA, Willman CL, Downing JR, Hunger SP.

Blood. 2011 Sep 15;118(11):3080-7. doi: 10.1182/blood-2011-03-341412. Epub 2011 Jun 16.

PMID:
21680795
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project.

Loh ML, Zhang J, Harvey RC, Roberts K, Payne-Turner D, Kang H, Wu G, Chen X, Becksfort J, Edmonson M, Buetow KH, Carroll WL, Chen IM, Wood B, Borowitz MJ, Devidas M, Gerhard DS, Bowman P, Larsen E, Winick N, Raetz E, Smith M, Downing JR, Willman CL, Mullighan CG, Hunger SP.

Blood. 2013 Jan 17;121(3):485-8. doi: 10.1182/blood-2012-04-422691. Epub 2012 Dec 4.

PMID:
23212523
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

JAK mutations in high-risk childhood acute lymphoblastic leukemia.

Mullighan CG, Zhang J, Harvey RC, Collins-Underwood JR, Schulman BA, Phillips LA, Tasian SK, Loh ML, Su X, Liu W, Devidas M, Atlas SR, Chen IM, Clifford RJ, Gerhard DS, Carroll WL, Reaman GH, Smith M, Downing JR, Hunger SP, Willman CL.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9414-8. doi: 10.1073/pnas.0811761106. Epub 2009 May 22.

PMID:
19470474
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia.

Case M, Matheson E, Minto L, Hassan R, Harrison CJ, Bown N, Bailey S, Vormoor J, Hall AG, Irving JA.

Cancer Res. 2008 Aug 15;68(16):6803-9. doi: 10.1158/0008-5472.CAN-08-0101.

PMID:
18701506
[PubMed - indexed for MEDLINE]
Free Article
5.

[Therapeutic strategies for childhood high-risk acute lymphoblastic leukemia].

Lu XT.

Beijing Da Xue Xue Bao. 2013 Apr 18;45(2):327-32. Review. Chinese.

PMID:
23591360
[PubMed - indexed for MEDLINE]
Free Article
6.

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.

Den Boer ML, van Slegtenhorst M, De Menezes RX, Cheok MH, Buijs-Gladdines JG, Peters ST, Van Zutven LJ, Beverloo HB, Van der Spek PJ, Escherich G, Horstmann MA, Janka-Schaub GE, Kamps WA, Evans WE, Pieters R.

Lancet Oncol. 2009 Feb;10(2):125-34. doi: 10.1016/S1470-2045(08)70339-5. Epub 2009 Jan 8.

PMID:
19138562
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study.

Chen IM, Harvey RC, Mullighan CG, Gastier-Foster J, Wharton W, Kang H, Borowitz MJ, Camitta BM, Carroll AJ, Devidas M, Pullen DJ, Payne-Turner D, Tasian SK, Reshmi S, Cottrell CE, Reaman GH, Bowman WP, Carroll WL, Loh ML, Winick NJ, Hunger SP, Willman CL.

Blood. 2012 Apr 12;119(15):3512-22. doi: 10.1182/blood-2011-11-394221. Epub 2012 Feb 24.

PMID:
22368272
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Parental exposure to medications and hydrocarbons and ras mutations in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Shu XO, Perentesis JP, Wen W, Buckley JD, Boyle E, Ross JA, Robison LL; Children's Oncology Group.

Cancer Epidemiol Biomarkers Prev. 2004 Jul;13(7):1230-5.

PMID:
15247135
[PubMed - indexed for MEDLINE]
Free Article
9.

Genomic profiling of high-risk acute lymphoblastic leukemia.

Collins-Underwood JR, Mullighan CG.

Leukemia. 2010 Oct;24(10):1676-85. doi: 10.1038/leu.2010.177. Epub 2010 Aug 26. Review.

PMID:
20739952
[PubMed - indexed for MEDLINE]
10.

RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia.

Perentesis JP, Bhatia S, Boyle E, Shao Y, Shu XO, Steinbuch M, Sather HN, Gaynon P, Kiffmeyer W, Envall-Fox J, Robison LL.

Leukemia. 2004 Apr;18(4):685-92.

PMID:
14990973
[PubMed - indexed for MEDLINE]
11.

Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.

Driessen EM, van Roon EH, Spijkers-Hagelstein JA, Schneider P, de Lorenzo P, Valsecchi MG, Pieters R, Stam RW.

Haematologica. 2013 Jun;98(6):937-44. doi: 10.3324/haematol.2012.067983. Epub 2013 Feb 12.

PMID:
23403319
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The molecular genetic makeup of acute lymphoblastic leukemia.

Mullighan CG.

Hematology Am Soc Hematol Educ Program. 2012;2012:389-96. doi: 10.1182/asheducation-2012.1.389. Review.

PMID:
23233609
[PubMed - indexed for MEDLINE]
Free Article
13.

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.

Harvey RC, Mullighan CG, Wang X, Dobbin KK, Davidson GS, Bedrick EJ, Chen IM, Atlas SR, Kang H, Ar K, Wilson CS, Wharton W, Murphy M, Devidas M, Carroll AJ, Borowitz MJ, Bowman WP, Downing JR, Relling M, Yang J, Bhojwani D, Carroll WL, Camitta B, Reaman GH, Smith M, Hunger SP, Willman CL.

Blood. 2010 Dec 2;116(23):4874-84. doi: 10.1182/blood-2009-08-239681. Epub 2010 Aug 10.

PMID:
20699438
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup.

Borssén M, Cullman I, Norén-Nyström U, Sundström C, Porwit A, Forestier E, Roos G.

Exp Hematol. 2011 Dec;39(12):1144-51. doi: 10.1016/j.exphem.2011.08.014. Epub 2011 Sep 10.

PMID:
21914494
[PubMed - indexed for MEDLINE]
15.

Mutations and deletions of the TP53 gene predict nonresponse to treatment and poor outcome in first relapse of childhood acute lymphoblastic leukemia.

Hof J, Krentz S, van Schewick C, Körner G, Shalapour S, Rhein P, Karawajew L, Ludwig WD, Seeger K, Henze G, von Stackelberg A, Hagemeier C, Eckert C, Kirschner-Schwabe R.

J Clin Oncol. 2011 Aug 10;29(23):3185-93. doi: 10.1200/JCO.2011.34.8144. Epub 2011 Jul 11.

PMID:
21747090
[PubMed - indexed for MEDLINE]
Free Article
16.

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia.

Kawamura M, Ohnishi H, Guo SX, Sheng XM, Minegishi M, Hanada R, Horibe K, Hongo T, Kaneko Y, Bessho F, Yanagisawa M, Sekiya T, Hayashi Y.

Leuk Res. 1999 Feb;23(2):115-26.

PMID:
10071127
[PubMed - indexed for MEDLINE]
17.

Analysis of p16 gene mutations and deletions in childhood acute lymphoblastic leukemias.

Lemos JA, Defavery R, Scrideli CA, Tone LG.

Sao Paulo Med J. 2003 Mar 5;121(2):58-62. Epub 2003 Jul 14.

PMID:
12870051
[PubMed - indexed for MEDLINE]
Free Article
18.

ATM gene alterations in childhood acute lymphoblastic leukemias.

Gumy Pause F, Wacker P, Maillet P, Betts D, Sappino AP.

Hum Mutat. 2003 May;21(5):554. Erratum in: Hum Mutat. 2003 Sep;22(3):256.

PMID:
12673804
[PubMed - indexed for MEDLINE]
19.

Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood.

Takeuchi S, Bartram CR, Seriu T, Miller CW, Tobler A, Janssen JW, Reiter A, Ludwig WD, Zimmermann M, Schwaller J, et al.

Blood. 1995 Jul 15;86(2):755-60.

PMID:
7606004
[PubMed - indexed for MEDLINE]
Free Article
20.

RAS mutations in pediatric leukemias with MLL gene rearrangements.

Mahgoub N, Parker RI, Hosler MR, Close P, Winick NJ, Masterson M, Shannon KM, Felix CA.

Genes Chromosomes Cancer. 1998 Mar;21(3):270-5.

PMID:
9523205
[PubMed - indexed for MEDLINE]

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