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Results: 1 to 20 of 86

1.

The hypoxia-inflammation link and potential drug targets.

Koeppen M, Eckle T, Eltzschig HK.

Curr Opin Anaesthesiol. 2011 Aug;24(4):363-9. doi: 10.1097/ACO.0b013e32834873fd. Review.

PMID:
21659868
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease.

Tanaka T, Nangaku M.

Curr Opin Nephrol Hypertens. 2010 Jan;19(1):43-50. doi: 10.1097/MNH.0b013e3283328eed. Review.

PMID:
19779337
[PubMed - indexed for MEDLINE]
3.

Hypoxia signaling during intestinal ischemia and inflammation.

Grenz A, Clambey E, Eltzschig HK.

Curr Opin Crit Care. 2012 Apr;18(2):178-85. doi: 10.1097/MCC.0b013e3283514bd0. Review.

PMID:
22322265
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury.

Jamadarkhana P, Chaudhary A, Chhipa L, Dubey A, Mohanan A, Gupta R, Deshpande S.

Am J Nephrol. 2012;36(3):208-18. Epub 2012 Aug 28.

PMID:
22948183
[PubMed - indexed for MEDLINE]
5.

The role of the hypoxia-inducible factor in tumor metabolism growth and invasion.

Brahimi-Horn C, Pouysségur J.

Bull Cancer. 2006 Aug;93(8):E73-80. Review.

PMID:
16935775
[PubMed - indexed for MEDLINE]
6.

Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: the role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B.

Winning S, Splettstoesser F, Fandrey J, Frede S.

J Immunol. 2010 Aug 1;185(3):1786-93. doi: 10.4049/jimmunol.0903244. Epub 2010 Jun 23.

PMID:
20574001
[PubMed - indexed for MEDLINE]
Free Article
7.

Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.

Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R.

Brain Res. 2009 Jul 14;1280:43-51. doi: 10.1016/j.brainres.2009.05.023. Epub 2009 May 18.

PMID:
19450570
[PubMed - indexed for MEDLINE]
8.

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.

Ratcliffe PJ.

Blood Purif. 2002;20(5):445-50. Review.

PMID:
12207089
[PubMed - indexed for MEDLINE]
9.

Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure.

Bernhardt WM, Câmpean V, Kany S, Jürgensen JS, Weidemann A, Warnecke C, Arend M, Klaus S, Günzler V, Amann K, Willam C, Wiesener MS, Eckardt KU.

J Am Soc Nephrol. 2006 Jul;17(7):1970-8. Epub 2006 Jun 8.

PMID:
16762988
[PubMed - indexed for MEDLINE]
Free Article
10.

Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.

Knowles HJ, Tian YM, Mole DR, Harris AL.

Circ Res. 2004 Jul 23;95(2):162-9. Epub 2004 Jun 10.

PMID:
15192023
[PubMed - indexed for MEDLINE]
Free Article
11.

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ.

J Biol Chem. 2004 Oct 8;279(41):42719-25. Epub 2004 Aug 9. Erratum in: J Biol Chem. 2004 Dec 24;279(52):54974.

PMID:
15302861
[PubMed - indexed for MEDLINE]
Free Article
12.

Prolyl hydroxylase inhibitor treatment confers whole-animal hypoxia tolerance.

Kasiganesan H, Sridharan V, Wright G.

Acta Physiol (Oxf). 2007 Jun;190(2):163-9. Epub 2007 Mar 30.

PMID:
17394573
[PubMed - indexed for MEDLINE]
13.

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors.

Huang LE, Ho V, Arany Z, Krainc D, Galson D, Tendler D, Livingston DM, Bunn HF.

Kidney Int. 1997 Feb;51(2):548-52. Review.

PMID:
9027736
[PubMed - indexed for MEDLINE]
14.

Increased activation of the hypoxia-inducible factor pathway in varicose veins.

Lim CS, Kiriakidis S, Paleolog EM, Davies AH.

J Vasc Surg. 2012 May;55(5):1427-39. doi: 10.1016/j.jvs.2011.10.111. Epub 2012 Jan 24.

PMID:
22277691
[PubMed - indexed for MEDLINE]
Free Article
15.
16.

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.

Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.

PLoS One. 2010 Jun 21;5(6):e11241. doi: 10.1371/journal.pone.0011241.

PMID:
20574527
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.

Hewitson KS, Schofield CJ, Ratcliffe PJ.

Methods Enzymol. 2007;435:25-42.

PMID:
17998047
[PubMed - indexed for MEDLINE]
18.

Hypoxia response in asthma: differential modulation on inflammation and epithelial injury.

Ahmad T, Kumar M, Mabalirajan U, Pattnaik B, Aggarwal S, Singh R, Singh S, Mukerji M, Ghosh B, Agrawal A.

Am J Respir Cell Mol Biol. 2012 Jul;47(1):1-10. doi: 10.1165/rcmb.2011-0203OC. Epub 2012 Feb 3.

PMID:
22312019
[PubMed - indexed for MEDLINE]
19.

Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.

McMahon S, Charbonneau M, Grandmont S, Richard DE, Dubois CM.

J Biol Chem. 2006 Aug 25;281(34):24171-81. Epub 2006 Jun 30.

PMID:
16815840
[PubMed - indexed for MEDLINE]
Free Article
20.

Hypoxia-inducible factor 1 in lower limb ischemia.

Ho TK, Abraham DJ, Black CM, Baker DM.

Vascular. 2006 Nov-Dec;14(6):321-7. Review.

PMID:
17150152
[PubMed - indexed for MEDLINE]

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