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Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology.

Pacurari M, Qian Y, Porter DW, Wolfarth M, Wan Y, Luo D, Ding M, Castranova V, Guo NL.

Toxicol Appl Pharmacol. 2011 Aug 15;255(1):18-31. doi: 10.1016/j.taap.2011.05.012. Epub 2011 May 23.


Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis.

Guo NL, Wan YW, Denvir J, Porter DW, Pacurari M, Wolfarth MG, Castranova V, Qian Y.

J Toxicol Environ Health A. 2012;75(18):1129-53. doi: 10.1080/15287394.2012.699852.


System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses.

Snyder-Talkington BN, Dymacek J, Porter DW, Wolfarth MG, Mercer RR, Pacurari M, Denvir J, Castranova V, Qian Y, Guo NL.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):476-89. doi: 10.1016/j.taap.2013.06.026. Epub 2013 Jul 8.


Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.

Sargent LM, Porter DW, Staska LM, Hubbs AF, Lowry DT, Battelli L, Siegrist KJ, Kashon ML, Mercer RR, Bauer AK, Chen BT, Salisbury JL, Frazer D, McKinney W, Andrew M, Tsuruoka S, Endo M, Fluharty KL, Castranova V, Reynolds SH.

Part Fibre Toxicol. 2014 Jan 9;11:3. doi: 10.1186/1743-8977-11-3.


Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes.

Porter DW, Hubbs AF, Mercer RR, Wu N, Wolfarth MG, Sriram K, Leonard S, Battelli L, Schwegler-Berry D, Friend S, Andrew M, Chen BT, Tsuruoka S, Endo M, Castranova V.

Toxicology. 2010 Mar 10;269(2-3):136-47. doi: 10.1016/j.tox.2009.10.017. Epub 2009 Oct 24.


Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies.

Snyder-Talkington BN, Dong C, Zhao X, Dymacek J, Porter DW, Wolfarth MG, Castranova V, Qian Y, Guo NL.

Toxicology. 2015 Feb 3;328:66-74. doi: 10.1016/j.tox.2014.12.012. Epub 2014 Dec 13.


Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes.

Mercer RR, Hubbs AF, Scabilloni JF, Wang L, Battelli LA, Friend S, Castranova V, Porter DW.

Part Fibre Toxicol. 2011 Jul 22;8:21. doi: 10.1186/1743-8977-8-21.


mRNA and miRNA Regulatory Networks Reflective of Multi-Walled Carbon Nanotube-Induced Lung Inflammatory and Fibrotic Pathologies in Mice.

Dymacek J, Snyder-Talkington BN, Porter DW, Mercer RR, Wolfarth MG, Castranova V, Qian Y, Guo NL.

Toxicol Sci. 2015 Mar;144(1):51-64. doi: 10.1093/toxsci/kfu262. Epub 2014 Dec 18.


Expansion of cardiac ischemia/reperfusion injury after instillation of three forms of multi-walled carbon nanotubes.

Urankar RN, Lust RM, Mann E, Katwa P, Wang X, Podila R, Hilderbrand SC, Harrison BS, Chen P, Ke PC, Rao AM, Brown JM, Wingard CJ.

Part Fibre Toxicol. 2012 Oct 16;9:38. doi: 10.1186/1743-8977-9-38.


Acute pulmonary response of mice to multi-wall carbon nanotubes.

Han SG, Andrews R, Gairola CG.

Inhal Toxicol. 2010 Mar;22(4):340-7. doi: 10.3109/08958370903359984.


Effects of lung exposure to carbon nanotubes on female fertility and pregnancy. A study in mice.

Hougaard KS, Jackson P, Kyjovska ZO, Birkedal RK, De Temmerman PJ, Brunelli A, Verleysen E, Madsen AM, Saber AT, Pojana G, Mast J, Marcomini A, Jensen KA, Wallin H, Szarek J, Mortensen A, Vogel U.

Reprod Toxicol. 2013 Nov;41:86-97. doi: 10.1016/j.reprotox.2013.05.006. Epub 2013 May 25.


Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes) relative to alpha-quartz following a single 6h inhalation exposure of rats and a 3 months post-exposure period.

Ellinger-Ziegelbauer H, Pauluhn J.

Toxicology. 2009 Dec 21;266(1-3):16-29. doi: 10.1016/j.tox.2009.10.007. Epub 2009 Oct 28.


Differential effects of long and short carbon nanotubes on the gas-exchange region of the mouse lung.

Mühlfeld C, Poland CA, Duffin R, Brandenberger C, Murphy FA, Rothen-Rutishauser B, Gehr P, Donaldson K.

Nanotoxicology. 2012 Dec;6:867-79. doi: 10.3109/17435390.2011.626533. Epub 2011 Oct 24.


Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway.

Chen T, Nie H, Gao X, Yang J, Pu J, Chen Z, Cui X, Wang Y, Wang H, Jia G.

Toxicol Lett. 2014 Apr 21;226(2):150-62. doi: 10.1016/j.toxlet.2014.02.004. Epub 2014 Feb 12.


Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice.

Zeidler-Erdely PC, Kashon ML, Li S, Antonini JM.

Respir Res. 2010 Jun 3;11:70. doi: 10.1186/1465-9921-11-70.


Pulmonary response of mice to a sequential exposure of side-stream cigarette smoke and multi-walled carbon nanotubes.

Han SG.

Inhal Toxicol. 2014 May;26(6):327-32. doi: 10.3109/08958378.2014.890683. Epub 2014 Mar 24.


Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes.

Mercer RR, Hubbs AF, Scabilloni JF, Wang L, Battelli LA, Schwegler-Berry D, Castranova V, Porter DW.

Part Fibre Toxicol. 2010 Oct 4;7:28. doi: 10.1186/1743-8977-7-28.


Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells.

Søs Poulsen S, Jacobsen NR, Labib S, Wu D, Husain M, Williams A, Bøgelund JP, Andersen O, Købler C, Mølhave K, Kyjovska ZO, Saber AT, Wallin H, Yauk CL, Vogel U, Halappanavar S.

PLoS One. 2013 Nov 19;8(11):e80452. doi: 10.1371/journal.pone.0080452. eCollection 2013.


Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells.

Snyder-Talkington BN, Pacurari M, Dong C, Leonard SS, Schwegler-Berry D, Castranova V, Qian Y, Guo NL.

Toxicol Sci. 2013 May;133(1):79-89. doi: 10.1093/toxsci/kft019. Epub 2013 Feb 1. Erratum in: Toxicol Sci. 2013 Aug;134(2):427.


Differential toxic responses between pristine and functionalized multiwall nanotubes involve induction of autophagy accumulation in murine lung.

Yu KN, Kim JE, Seo HW, Chae C, Cho MH.

J Toxicol Environ Health A. 2013;76(23):1282-92. doi: 10.1080/15287394.2013.850137.

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