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Results: 1 to 20 of 185

1.

Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding.

Alhashem YN, Vinjamur DS, Basu M, Klingmüller U, Gaensler KM, Lloyd JA.

J Biol Chem. 2011 Jul 15;286(28):24819-27. doi: 10.1074/jbc.M111.247536. Epub 2011 May 24.

PMID:
21610079
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis.

Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M.

Mol Cell Biol. 2012 Jul;32(13):2628-44. doi: 10.1128/MCB.00104-12. Epub 2012 May 7.

PMID:
22566683
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

KLF2 is essential for primitive erythropoiesis and regulates the human and murine embryonic beta-like globin genes in vivo.

Basu P, Morris PE, Haar JL, Wani MA, Lingrel JB, Gaensler KM, Lloyd JA.

Blood. 2005 Oct 1;106(7):2566-71. Epub 2005 Jun 9.

PMID:
15947087
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis.

Basu P, Lung TK, Lemsaddek W, Sargent TG, Williams DC Jr, Basu M, Redmond LC, Lingrel JB, Haar JL, Lloyd JA.

Blood. 2007 Nov 1;110(9):3417-25. Epub 2007 Aug 3.

PMID:
17675555
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.

Esteghamat F, Gillemans N, Bilic I, van den Akker E, Cantù I, van Gent T, Klingmüller U, van Lom K, von Lindern M, Grosveld F, Bryn van Dijk T, Busslinger M, Philipsen S.

Blood. 2013 Mar 28;121(13):2553-62. doi: 10.1182/blood-2012-06-434530. Epub 2013 Jan 29.

PMID:
23361909
[PubMed - indexed for MEDLINE]
Free Article
6.

Krüppel-like factor 2 regulated gene expression in mouse embryonic yolk sac erythroid cells.

Redmond LC, Dumur CI, Archer KJ, Grayson DR, Haar JL, Lloyd JA.

Blood Cells Mol Dis. 2011 Jun 15;47(1):1-11. doi: 10.1016/j.bcmd.2011.03.002. Epub 2011 Apr 29.

PMID:
21530336
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Three fingers on the switch: Krüppel-like factor 1 regulation of γ-globin to β-globin gene switching.

Tallack MR, Perkins AC.

Curr Opin Hematol. 2013 May;20(3):193-200. doi: 10.1097/MOH.0b013e32835f59ba. Review.

PMID:
23474875
[PubMed - indexed for MEDLINE]
8.

Krϋppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation.

Vinjamur DS, Wade KJ, Mohamad SF, Haar JL, Sawyer ST, Lloyd JA.

Haematologica. 2014 Aug 22. pii: haematol.2014.104943. [Epub ahead of print]

PMID:
25150253
[PubMed - as supplied by publisher]
Free Article
9.

Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.

Funnell AP, Vernimmen D, Lim WF, Mak KS, Wienert B, Martyn GE, Artuz CM, Burdach J, Quinlan KG, Higgs DR, Whitelaw E, Pearson RC, Crossley M.

BMC Mol Biol. 2014 May 16;15:8. doi: 10.1186/1471-2199-15-8.

PMID:
24885809
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching.

Zhou D, Liu K, Sun CW, Pawlik KM, Townes TM.

Nat Genet. 2010 Sep;42(9):742-4. doi: 10.1038/ng.637. Epub 2010 Aug 1.

PMID:
20676097
[PubMed - indexed for MEDLINE]
11.

The role of EKLF in human beta-globin gene competition.

Wijgerde M, Gribnau J, Trimborn T, Nuez B, Philipsen S, Grosveld F, Fraser P.

Genes Dev. 1996 Nov 15;10(22):2894-902.

PMID:
8918890
[PubMed - indexed for MEDLINE]
Free Article
12.

A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo.

McGrath KE, Frame JM, Fromm GJ, Koniski AD, Kingsley PD, Little J, Bulger M, Palis J.

Blood. 2011 Apr 28;117(17):4600-8. doi: 10.1182/blood-2010-12-325357. Epub 2011 Mar 4.

PMID:
21378272
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element.

Zhang P, Basu P, Redmond LC, Morris PE, Rupon JW, Ginder GD, Lloyd JA.

Blood Cells Mol Dis. 2005 Sep-Oct;35(2):227-35.

PMID:
16023392
[PubMed - indexed for MEDLINE]
14.

Krüppel-like factor 2 is required for normal mouse cardiac development.

Chiplunkar AR, Lung TK, Alhashem Y, Koppenhaver BA, Salloum FN, Kukreja RC, Haar JL, Lloyd JA.

PLoS One. 2013;8(2):e54891. doi: 10.1371/journal.pone.0054891. Epub 2013 Feb 14.

PMID:
23457456
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene.

Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S.

Development. 1996 Dec;122(12):3991-9.

PMID:
9012519
[PubMed - indexed for MEDLINE]
Free Article
16.

Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control region.

Tewari R, Gillemans N, Wijgerde M, Nuez B, von Lindern M, Grosveld F, Philipsen S.

EMBO J. 1998 Apr 15;17(8):2334-41.

PMID:
9545245
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells.

Kalra IS, Alam MM, Choudhary PK, Pace BS.

Br J Haematol. 2011 Jul;154(2):248-59. doi: 10.1111/j.1365-2141.2011.08710.x. Epub 2011 May 3.

PMID:
21539536
[PubMed - indexed for MEDLINE]
18.

The Krüppel-like factor 2 and Krüppel-like factor 4 genes interact to maintain endothelial integrity in mouse embryonic vasculogenesis.

Chiplunkar AR, Curtis BC, Eades GL, Kane MS, Fox SJ, Haar JL, Lloyd JA.

BMC Dev Biol. 2013 Nov 22;13:40. doi: 10.1186/1471-213X-13-40.

PMID:
24261709
[PubMed - indexed for MEDLINE]
Free Article
19.

Major erythrocyte membrane protein genes in EKLF-deficient mice.

Nilson DG, Sabatino DE, Bodine DM, Gallagher PG.

Exp Hematol. 2006 Jun;34(6):705-12.

PMID:
16728274
[PubMed - indexed for MEDLINE]
20.

Subcellular transport of EKLF and switch-on of murine adult beta maj globin gene transcription.

Shyu YC, Lee TL, Wen SC, Chen H, Hsiao WY, Chen X, Hwang J, Shen CK.

Mol Cell Biol. 2007 Mar;27(6):2309-23. Epub 2007 Jan 22.

PMID:
17242208
[PubMed - indexed for MEDLINE]
Free PMC Article

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