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Results: 1 to 20 of 122

1.

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation.

Bhattacharyya S, Zhao Y, Kay TW, Muglia LJ.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9554-9. doi: 10.1073/pnas.1017296108. Epub 2011 May 23.

PMID:
21606371
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.

Prêle CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH.

J Immunol. 2008 Dec 1;181(11):8018-26.

PMID:
19017994
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.

Gingras S, Parganas E, de Pauw A, Ihle JN, Murray PJ.

J Biol Chem. 2004 Dec 24;279(52):54702-7. Epub 2004 Oct 18.

PMID:
15491990
[PubMed - indexed for MEDLINE]
Free Article
4.

SOCS1-negative feedback of STAT1 activation is a key pathway in the dsRNA-induced innate immune response of human keratinocytes.

Dai X, Sayama K, Yamasaki K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yahata Y, Yang L, Yoshimura A, Hashimoto K.

J Invest Dermatol. 2006 Jul;126(7):1574-81. Epub 2006 Apr 20.

PMID:
16628196
[PubMed - indexed for MEDLINE]
Free Article
5.

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

Baetz A, Frey M, Heeg K, Dalpke AH.

J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.

PMID:
15491991
[PubMed - indexed for MEDLINE]
Free Article
6.

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

Gotoh K, Tanaka Y, Nishikimi A, Nakamura R, Yamada H, Maeda N, Ishikawa T, Hoshino K, Uruno T, Cao Q, Higashi S, Kawaguchi Y, Enjoji M, Takayanagi R, Kaisho T, Yoshikai Y, Fukui Y.

J Exp Med. 2010 Apr 12;207(4):721-30. doi: 10.1084/jem.20091776. Epub 2010 Mar 15.

PMID:
20231379
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Retinol suppresses the activation of Toll-like receptors in MyD88- and STAT1-independent manners.

Kim SY, Koo JE, Song MR, Lee JY.

Inflammation. 2013 Apr;36(2):426-33. doi: 10.1007/s10753-012-9562-2.

PMID:
23086657
[PubMed - indexed for MEDLINE]
8.

Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways.

Sugiyama Y, Kakoi K, Kimura A, Takada I, Kashiwagi I, Wakabayashi Y, Morita R, Nomura M, Yoshimura A.

Int Immunol. 2012 Apr;24(4):253-65. doi: 10.1093/intimm/dxr126. Epub 2012 Feb 13.

PMID:
22331441
[PubMed - indexed for MEDLINE]
Free Article
9.

Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.

Zhao W, Wang L, Zhang M, Wang P, Zhang L, Yuan C, Qi J, Qiao Y, Kuo PC, Gao C.

J Biol Chem. 2011 Feb 18;286(7):5519-28. doi: 10.1074/jbc.M110.149823. Epub 2010 Dec 10.

PMID:
21148557
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Suppressor of cytokine signaling 1 protects rat pancreatic islets from cytokine-induced apoptosis through Janus kinase/signal transducers and activators of transcription pathway.

Sun Q, Xiang RL, Yang YL, Feng K, Zhang K, Ding WY.

Chin Med J (Engl). 2013 Nov;126(21):4048-53.

PMID:
24229672
[PubMed - indexed for MEDLINE]
Free Article
11.

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

Gautier G, Humbert M, Deauvieau F, Scuiller M, Hiscott J, Bates EE, Trinchieri G, Caux C, Garrone P.

J Exp Med. 2005 May 2;201(9):1435-46. Epub 2005 Apr 25.

PMID:
15851485
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
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14.

Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: alternatively activated STAT1 negatively regulates TLR signaling in macrophages.

Schroder K, Spille M, Pilz A, Lattin J, Bode KA, Irvine KM, Burrows AD, Ravasi T, Weighardt H, Stacey KJ, Decker T, Hume DA, Dalpke AH, Sweet MJ.

J Immunol. 2007 Sep 15;179(6):3495-503.

PMID:
17785783
[PubMed - indexed for MEDLINE]
Free Article
15.

IFN-gamma-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes.

Cho HJ, Kim SK, Jin SM, Hwang EM, Kim YS, Huh K, Mook-Jung I.

Glia. 2007 Feb;55(3):253-62.

PMID:
17091494
[PubMed - indexed for MEDLINE]
16.

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways.

Gorina R, Font-Nieves M, Márquez-Kisinousky L, Santalucia T, Planas AM.

Glia. 2011 Feb;59(2):242-55. doi: 10.1002/glia.21094.

PMID:
21125645
[PubMed - indexed for MEDLINE]
17.

Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4.

Doyle SE, O'Connell R, Vaidya SA, Chow EK, Yee K, Cheng G.

J Immunol. 2003 Apr 1;170(7):3565-71.

PMID:
12646618
[PubMed - indexed for MEDLINE]
Free Article
18.

Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.

Dong LW, Kong XN, Yan HX, Yu LX, Chen L, Yang W, Liu Q, Huang DD, Wu MC, Wang HY.

Mol Immunol. 2008 Jun;45(11):3025-35. doi: 10.1016/j.molimm.2008.03.012. Epub 2008 May 8.

PMID:
18471880
[PubMed - indexed for MEDLINE]
19.

Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression.

Serezani CH, Lewis C, Jancar S, Peters-Golden M.

J Clin Invest. 2011 Feb;121(2):671-82. doi: 10.1172/JCI43302. Epub 2011 Jan 4.

PMID:
21206089
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling.

Wormald S, Zhang JG, Krebs DL, Mielke LA, Silver J, Alexander WS, Speed TP, Nicola NA, Hilton DJ.

J Biol Chem. 2006 Apr 21;281(16):11135-43. Epub 2006 Feb 10.

PMID:
16473883
[PubMed - indexed for MEDLINE]
Free Article

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