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Items: 1 to 20 of 79

1.

Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.

Masharani UB, Maddux BA, Li X, Sakkas GK, Mulligan K, Schambelan M, Goldfine ID, Youngren JF.

PLoS One. 2011 May 11;6(5):e19878. doi: 10.1371/journal.pone.0019878.

2.

Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle.

Virkamäki A, Korsheninnikova E, Seppälä-Lindroos A, Vehkavaara S, Goto T, Halavaara J, Häkkinen AM, Yki-Järvinen H.

Diabetes. 2001 Oct;50(10):2337-43.

3.

Elevated fasting insulin concentrations associate with impaired insulin signaling in skeletal muscle of healthy subjects independent of obesity.

Korsheninnikova E, Seppälä-Lindroos A, Vehkavaara S, Goto T, Virkamäki A.

Diabetes Metab Res Rev. 2002 May-Jun;18(3):209-16.

PMID:
12112939
4.
5.

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

Jacob S, Machann J, Rett K, Brechtel K, Volk A, Renn W, Maerker E, Matthaei S, Schick F, Claussen CD, Häring HU.

Diabetes. 1999 May;48(5):1113-9.

PMID:
10331418
8.

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans.

Adams JM 2nd, Pratipanawatr T, Berria R, Wang E, DeFronzo RA, Sullards MC, Mandarino LJ.

Diabetes. 2004 Jan;53(1):25-31.

9.
10.

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner.

de Alvaro C, Teruel T, Hernandez R, Lorenzo M.

J Biol Chem. 2004 Apr 23;279(17):17070-8. Epub 2004 Feb 4.

11.

Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

Storgaard H, Song XM, Jensen CB, Madsbad S, Björnholm M, Vaag A, Zierath JR.

Diabetes. 2001 Dec;50(12):2770-8. Erratum in: Diabetes 2002 Feb;51(2):552.

13.
14.

Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

Ogihara T, Asano T, Ando K, Chiba Y, Sekine N, Sakoda H, Anai M, Onishi Y, Fujishiro M, Ono H, Shojima N, Inukai K, Fukushima Y, Kikuchi M, Fujita T.

Diabetes. 2001 Mar;50(3):573-83.

15.

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.

16.

Elevated plasma cell membrane glycoprotein levels and diminished insulin receptor autophosphorylation in obese, insulin-resistant rhesus monkeys.

Pender C, Ortmeyer HK, Hansen BC, Goldfine ID, Youngren JF.

Metabolism. 2002 Apr;51(4):465-70.

PMID:
11912555
17.

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity.

Blüher M, Bashan N, Shai I, Harman-Boehm I, Tarnovscki T, Avinaoch E, Stumvoll M, Dietrich A, Klöting N, Rudich A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2507-15. doi: 10.1210/jc.2009-0002. Epub 2009 Apr 7.

PMID:
19351724
18.

Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle.

Vendelbo MH, Clasen BF, Treebak JT, Møller L, Krusenstjerna-Hafstrøm T, Madsen M, Nielsen TS, Stødkilde-Jørgensen H, Pedersen SB, Jørgensen JO, Goodyear LJ, Wojtaszewski JF, Møller N, Jessen N.

Am J Physiol Endocrinol Metab. 2012 Jan 15;302(2):E190-200. doi: 10.1152/ajpendo.00207.2011. Epub 2011 Oct 25.

20.

High-fat feeding increases insulin receptor and IRS-1 coimmunoprecipitation with SOCS-3, IKKalpha/beta phosphorylation and decreases PI-3 kinase activity in muscle.

Yaspelkis BB 3rd, Kvasha IA, Figueroa TY.

Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1709-15. doi: 10.1152/ajpregu.00117.2009. Epub 2009 Apr 22.

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