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Results: 1 to 20 of 138

1.

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity.

Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS.

Nature. 2011 May 26;473(7348):528-31. doi: 10.1038/nature09968. Epub 2011 May 1.

PMID:
21532591
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity.

Park SW, Zhou Y, Lee J, Lee J, Ozcan U.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19320-5. doi: 10.1073/pnas.1012044107. Epub 2010 Oct 25.

PMID:
20974941
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis.

Zhang J, Li Y, Jiang S, Yu H, An W.

Am J Physiol Cell Physiol. 2014 Feb 1;306(3):C279-90. doi: 10.1152/ajpcell.00117.2013. Epub 2013 Nov 27.

PMID:
24284796
[PubMed - indexed for MEDLINE]
4.

Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress.

Agouni A, Mody N, Owen C, Czopek A, Zimmer D, Bentires-Alj M, Bence KK, Delibegović M.

Biochem J. 2011 Sep 1;438(2):369-78. doi: 10.1042/BJ20110373.

PMID:
21605081
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling.

Fu S, Watkins SM, Hotamisligil GS.

Cell Metab. 2012 May 2;15(5):623-34. doi: 10.1016/j.cmet.2012.03.007. Review.

PMID:
22560215
[PubMed - indexed for MEDLINE]
Free Article
6.

Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.

Huang J, Jia Y, Fu T, Viswakarma N, Bai L, Rao MS, Zhu Y, Borensztajn J, Reddy JK.

FASEB J. 2012 Feb;26(2):628-38. doi: 10.1096/fj.11-194019. Epub 2011 Oct 18.

PMID:
22009939
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction.

Ceylan-Isik AF, Sreejayan N, Ren J.

J Mol Cell Cardiol. 2011 Jan;50(1):107-16. doi: 10.1016/j.yjmcc.2010.10.023. Epub 2010 Oct 28.

PMID:
21035453
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

[Importance of phospholipids in ER stress and fatty liver disease].

Flamment M, Foufelle F.

Med Sci (Paris). 2012 Jan;28(1):13-5. doi: 10.1051/medsci/2012281004. Epub 2012 Jan 27. French. No abstract available.

PMID:
22289818
[PubMed - indexed for MEDLINE]
Free Article
9.

Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo.

Dong Y, Zhang M, Liang B, Xie Z, Zhao Z, Asfa S, Choi HC, Zou MH.

Circulation. 2010 Feb 16;121(6):792-803. doi: 10.1161/CIRCULATIONAHA.109.900928. Epub 2010 Feb 1.

PMID:
20124121
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The role of phospholipids in the biological activity and structure of the endoplasmic reticulum.

Lagace TA, Ridgway ND.

Biochim Biophys Acta. 2013 Nov;1833(11):2499-510. doi: 10.1016/j.bbamcr.2013.05.018. Epub 2013 May 24. Review.

PMID:
23711956
[PubMed - indexed for MEDLINE]
Free Article
11.

How does protein misfolding in the endoplasmic reticulum affect lipid metabolism in the liver?

Wang S, Kaufman RJ.

Curr Opin Lipidol. 2014 Apr;25(2):125-32. doi: 10.1097/MOL.0000000000000056. Review.

PMID:
24565920
[PubMed - indexed for MEDLINE]
12.

Human immunodeficiency virus protease inhibitors modulate Ca2+ homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes.

Kao E, Shinohara M, Feng M, Lau MY, Ji C.

Hepatology. 2012 Aug;56(2):594-604. doi: 10.1002/hep.25702. Epub 2012 Jun 11.

PMID:
22407670
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

ILDR2: an endoplasmic reticulum resident molecule mediating hepatic lipid homeostasis.

Watanabe K, Watson E, Cremona ML, Millings EJ, Lefkowitch JH, Fischer SG, LeDuc CA, Leibel RL.

PLoS One. 2013 Jun 24;8(6):e67234. doi: 10.1371/journal.pone.0067234. Print 2013.

PMID:
23826244
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

β-adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines.

George I, Sabbah HN, Xu K, Wang N, Wang J.

Cardiovasc Res. 2011 Aug 1;91(3):447-55. doi: 10.1093/cvr/cvr106. Epub 2011 Apr 14.

PMID:
21493701
[PubMed - indexed for MEDLINE]
Free Article
15.

PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells.

Moore CE, Omikorede O, Gomez E, Willars GB, Herbert TP.

Mol Endocrinol. 2011 Feb;25(2):315-26. doi: 10.1210/me.2010-0309. Epub 2010 Dec 30.

PMID:
21193559
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Calcium efflux from the endoplasmic reticulum leads to β-cell death.

Hara T, Mahadevan J, Kanekura K, Hara M, Lu S, Urano F.

Endocrinology. 2014 Mar;155(3):758-68. doi: 10.1210/en.2013-1519. Epub 2013 Jan 1.

PMID:
24424032
[PubMed - indexed for MEDLINE]
17.

Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction.

Kujiraoka T, Satoh Y, Ayaori M, Shiraishi Y, Arai-Nakaya Y, Hakuno D, Yada H, Kuwada N, Endo S, Isoda K, Adachi T.

J Am Heart Assoc. 2013 Aug 16;2(4):e000361. doi: 10.1161/JAHA.113.000361.

PMID:
23954796
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting.

Fu S, Fan J, Blanco J, Gimenez-Cassina A, Danial NN, Watkins SM, Hotamisligil GS.

PLoS Genet. 2012 Aug;8(8):e1002902. doi: 10.1371/journal.pgen.1002902. Epub 2012 Aug 23.

PMID:
22927828
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation.

Dong H, Huang H, Yun X, Kim DS, Yue Y, Wu H, Sutter A, Chavin KD, Otterbein LE, Adams DB, Kim YB, Wang H.

Endocrinology. 2014 Mar;155(3):818-28. doi: 10.1210/en.2013-1667. Epub 2014 Jan 1.

PMID:
24424052
[PubMed - indexed for MEDLINE]
20.

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD.

Diabetes. 2009 Feb;58(2):422-32. doi: 10.2337/db07-1762. Epub 2008 Nov 25.

PMID:
19033399
[PubMed - indexed for MEDLINE]
Free PMC Article
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