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Results: 1 to 20 of 154

1.

Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.

Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, Wang A, Wilbert D, Patel RM, Ferris J, Diener J, Allen M, Lim S, Syu LJ, Verhaegen M, Dlugosz AA.

J Clin Invest. 2011 May;121(5):1768-81. doi: 10.1172/JCI46307. Epub 2011 Apr 25.

PMID:
21519145
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle.

Hutchin ME, Kariapper MS, Grachtchouk M, Wang A, Wei L, Cummings D, Liu J, Michael LE, Glick A, Dlugosz AA.

Genes Dev. 2005 Jan 15;19(2):214-23. Epub 2004 Dec 29.

PMID:
15625189
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Wounding mobilizes hair follicle stem cells to form tumors.

Wong SY, Reiter JF.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4093-8. doi: 10.1073/pnas.1013098108. Epub 2011 Feb 14.

PMID:
21321207
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity.

Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ.

Cancer Prev Res (Phila). 2010 Oct;3(10):1222-34. doi: 10.1158/1940-6207.CAPR-10-0082. Epub 2010 Sep 21.

PMID:
20858761
[PubMed - indexed for MEDLINE]
5.

Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.

Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC.

Development. 2012 Nov;139(22):4152-61. doi: 10.1242/dev.081190. Epub 2012 Oct 3.

PMID:
23034632
[PubMed - indexed for MEDLINE]
Free Article
6.

GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells.

Eichberger T, Kaser A, Pixner C, Schmid C, Klingler S, Winklmayr M, Hauser-Kronberger C, Aberger F, Frischauf AM.

J Biol Chem. 2008 May 2;283(18):12426-37. doi: 10.1074/jbc.M707117200. Epub 2008 Mar 3.

PMID:
18319260
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Identification of the cell lineage at the origin of basal cell carcinoma.

Youssef KK, Van Keymeulen A, Lapouge G, Beck B, Michaux C, Achouri Y, Sotiropoulou PA, Blanpain C.

Nat Cell Biol. 2010 Mar;12(3):299-305. doi: 10.1038/ncb2031. Epub 2010 Feb 14.

PMID:
20154679
[PubMed - indexed for MEDLINE]
9.

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling.

Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA.

Nat Genet. 2008 Sep;40(9):1130-5. doi: 10.1038/ng.192.

PMID:
19165927
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hair cycle regulation of Hedgehog signal reception.

Oro AE, Higgins K.

Dev Biol. 2003 Mar 15;255(2):238-48.

PMID:
12648487
[PubMed - indexed for MEDLINE]
11.

Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.

Depianto D, Kerns ML, Dlugosz AA, Coulombe PA.

Nat Genet. 2010 Oct;42(10):910-4. doi: 10.1038/ng.665. Epub 2010 Sep 26.

PMID:
20871598
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hair cycle-dependent basal cell carcinoma tumorigenesis in Ptc1neo67/+ mice exposed to radiation.

Mancuso M, Leonardi S, Tanori M, Pasquali E, Pierdomenico M, Rebessi S, Di Majo V, Covelli V, Pazzaglia S, Saran A.

Cancer Res. 2006 Jul 1;66(13):6606-14.

PMID:
16818633
[PubMed - indexed for MEDLINE]
Free Article
13.

Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype.

Sheng H, Goich S, Wang A, Grachtchouk M, Lowe L, Mo R, Lin K, de Sauvage FJ, Sasaki H, Hui CC, Dlugosz AA.

Cancer Res. 2002 Sep 15;62(18):5308-16.

PMID:
12235001
[PubMed - indexed for MEDLINE]
Free Article
14.

Differential response of epithelial stem cell populations in hair follicles to TGF-╬▓ signaling.

Lin HY, Yang LT.

Dev Biol. 2013 Jan 15;373(2):394-406. doi: 10.1016/j.ydbio.2012.10.021. Epub 2012 Oct 26.

PMID:
23103542
[PubMed - indexed for MEDLINE]
Free Article
15.

Molecular conversations and the development of the hair follicle and basal cell carcinoma.

Harris PJ, Takebe N, Ivy SP.

Cancer Prev Res (Phila). 2010 Oct;3(10):1217-21. doi: 10.1158/1940-6207.CAPR-10-0210. Epub 2010 Sep 21. Review.

PMID:
20858758
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice.

Mancuso M, Pazzaglia S, Tanori M, Hahn H, Merola P, Rebessi S, Atkinson MJ, Di Majo V, Covelli V, Saran A.

Cancer Res. 2004 Feb 1;64(3):934-41.

PMID:
14871823
[PubMed - indexed for MEDLINE]
Free Article
17.

Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias.

Kan L, Liu Y, McGuire TL, Bonaguidi MA, Kessler JA.

J Biomed Sci. 2011 Dec 14;18:92. doi: 10.1186/1423-0127-18-92.

PMID:
22168923
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment.

Vidal VP, Chaboissier MC, L├╝tzkendorf S, Cotsarelis G, Mill P, Hui CC, Ortonne N, Ortonne JP, Schedl A.

Curr Biol. 2005 Aug 9;15(15):1340-51.

PMID:
16085486
[PubMed - indexed for MEDLINE]
Free Article
19.

The magnitude of hedgehog signaling activity defines skin tumor phenotype.

Grachtchouk V, Grachtchouk M, Lowe L, Johnson T, Wei L, Wang A, de Sauvage F, Dlugosz AA.

EMBO J. 2003 Jun 2;22(11):2741-51.

PMID:
12773389
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice.

Wang GY, Wang J, Mancianti ML, Epstein EH Jr.

Cancer Cell. 2011 Jan 18;19(1):114-24. doi: 10.1016/j.ccr.2010.11.007. Epub 2011 Jan 6.

PMID:
21215705
[PubMed - indexed for MEDLINE]
Free PMC Article

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