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CXCL4 and CXCL10 predict risk of fatal cerebral malaria.

Wilson NO, Jain V, Roberts CE, Lucchi N, Joel PK, Singh MP, Nagpal AC, Dash AP, Udhayakumar V, Singh N, Stiles JK.

Dis Markers. 2011;30(1):39-49. doi: 10.3233/DMA-2011-0763.


Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India.

Jain V, Armah HB, Tongren JE, Ned RM, Wilson NO, Crawford S, Joel PK, Singh MP, Nagpal AC, Dash AP, Udhayakumar V, Singh N, Stiles JK.

Malar J. 2008 May 19;7:83. doi: 10.1186/1475-2875-7-83.


Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India.

Jain V, Lucchi NW, Wilson NO, Blackstock AJ, Nagpal AC, Joel PK, Singh MP, Udhayakumar V, Stiles JK, Singh N.

Malar J. 2011 Dec 23;10:383. doi: 10.1186/1475-2875-10-383.


Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children.

Armah HB, Wilson NO, Sarfo BY, Powell MD, Bond VC, Anderson W, Adjei AA, Gyasi RK, Tettey Y, Wiredu EK, Tongren JE, Udhayakumar V, Stiles JK.

Malar J. 2007 Nov 12;6:147.


CXCL10 gene promoter polymorphism -1447A>G correlates with plasma CXCL10 levels and is associated with male susceptibility to cerebral malaria.

Wilson N, Driss A, Solomon W, Dickinson-Copeland C, Salifu H, Jain V, Singh N, Stiles J.

PLoS One. 2013 Dec 9;8(12):e81329. doi: 10.1371/journal.pone.0081329. eCollection 2013.


Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria.

Wilson NO, Solomon W, Anderson L, Patrickson J, Pitts S, Bond V, Liu M, Stiles JK.

PLoS One. 2013 Apr 5;8(4):e60898. doi: 10.1371/journal.pone.0060898. Print 2013.


Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children.

Lovegrove FE, Tangpukdee N, Opoka RO, Lafferty EI, Rajwans N, Hawkes M, Krudsood S, Looareesuwan S, John CC, Liles WC, Kain KC.

PLoS One. 2009;4(3):e4912. doi: 10.1371/journal.pone.0004912. Epub 2009 Mar 20.


Serum chemokine receptor CXCR3 ligands are associated with progression, organ dysfunction and complications of chronic liver diseases.

Tacke F, Zimmermann HW, Berres ML, Trautwein C, Wasmuth HE.

Liver Int. 2011 Jul;31(6):840-9. doi: 10.1111/j.1478-3231.2011.02504.x. Epub 2011 Mar 10.


Peripheral CXCR3-associated chemokines as biomarkers of fibrosis in chronic hepatitis C virus infection.

Zeremski M, Dimova R, Brown Q, Jacobson IM, Markatou M, Talal AH.

J Infect Dis. 2009 Dec 1;200(11):1774-80. doi: 10.1086/646614.


CXCR3-mediated opposite effects of CXCL10 and CXCL4 on TH1 or TH2 cytokine production.

Romagnani P, Maggi L, Mazzinghi B, Cosmi L, Lasagni L, Liotta F, Lazzeri E, Angeli R, Rotondi M, Filì L, Parronchi P, Serio M, Maggi E, Romagnani S, Annunziato F.

J Allergy Clin Immunol. 2005 Dec;116(6):1372-9.


Expression of CXCR3 and its ligands CXCL9, -10 and -11 in paediatric opsoclonus-myoclonus syndrome.

Pranzatelli MR, Tate ED, McGee NR, Travelstead AL, Verhulst SJ, Ransohoff RM.

Clin Exp Immunol. 2013 Jun;172(3):427-36. doi: 10.1111/cei.12065.


Heme mediated STAT3 activation in severe malaria.

Liu M, Amodu AS, Pitts S, Patrickson J, Hibbert JM, Battle M, Ofori-Acquah SF, Stiles JK.

PLoS One. 2012;7(3):e34280. doi: 10.1371/journal.pone.0034280. Epub 2012 Mar 30.


Potential serological biomarkers of cerebral malaria.

Lucchi NW, Jain V, Wilson NO, Singh N, Udhayakumar V, Stiles JK.

Dis Markers. 2011;31(6):327-35. doi: 10.3233/DMA-2011-0854. Review.


Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria.

Campanella GS, Tager AM, El Khoury JK, Thomas SY, Abrazinski TA, Manice LA, Colvin RA, Luster AD.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4814-9. doi: 10.1073/pnas.0801544105. Epub 2008 Mar 17.


Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria.

Higgins SJ, Xing K, Kim H, Kain DC, Wang F, Dhabangi A, Musoke C, Cserti-Gazdewich CM, Tracey KJ, Kain KC, Liles WC.

Malar J. 2013 Mar 19;12:105. doi: 10.1186/1475-2875-12-105.


Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria.

Conroy AL, Lafferty EI, Lovegrove FE, Krudsood S, Tangpukdee N, Liles WC, Kain KC.

Malar J. 2009 Dec 15;8:295. doi: 10.1186/1475-2875-8-295.


An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4.

Lasagni L, Francalanci M, Annunziato F, Lazzeri E, Giannini S, Cosmi L, Sagrinati C, Mazzinghi B, Orlando C, Maggi E, Marra F, Romagnani S, Serio M, Romagnani P.

J Exp Med. 2003 Jun 2;197(11):1537-49.


A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria.

Prapansilp P, Medana I, Mai NT, Day NP, Phu NH, Yeo TW, Hien TT, White NJ, Anstey NM, Turner GD.

Malar J. 2013 Feb 5;12:50. doi: 10.1186/1475-2875-12-50.


Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency.

Miu J, Mitchell AJ, Müller M, Carter SL, Manders PM, McQuillan JA, Saunders BM, Ball HJ, Lu B, Campbell IL, Hunt NH.

J Immunol. 2008 Jan 15;180(2):1217-30.


CXC-chemokine ligand 10 in idiopathic pulmonary arterial hypertension: marker of improved survival.

Heresi GA, Aytekin M, Newman J, Dweik RA.

Lung. 2010 Jun;188(3):191-7. doi: 10.1007/s00408-010-9232-9. Epub 2010 Feb 26.

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